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Biomedical subjects

Michael G Conzemius

Publications and source records attributed to Michael G Conzemius.

20 records · Page 2Linked to original sources

Biological osteosynthesis versus traditional anatomic reconstruction of 20 long-bone fractures using an interlocking nail: 1994-2001.

OBJECTIVE: To observe differences in surgical and healing times as well as complication rates in dogs with a comminuted long-bone fracture stabilized with an interlocking nail (IN) using either anatomic or biologic repair. STUDY DESIGN: Retrospective study. ANIMALS: Twenty client-owned dogs with comminuted long-bone fractures. METHODS: Medical records for dogs with fractures repaired during a 7-year period were reviewed; 20 dogs had repair with an IN nail and radiographic evidence of healing. These 20 dogs where divided into 2 groups, anatomic (11 dogs) and biological (9) repair, for statistical evaluation. Surgical and healing time and complication rates were compared between groups. RESULTS: Median surgical times were: anatomic (95 minutes) and biologic (110 minutes; P=.06). Median healing times were anatomic (8 weeks) and biologic (6 weeks; P=.04). No statistical differences were observed in complication rates (the likelihood that a case required a second surgery [P=.58], the likelihood of a complication that was managed non-surgically [P=.27]). Use of a bone graft did not shorten healing times (P=.55). CONCLUSIONS: Biological osteosynthesis provides clinical advantages over anatomic reconstruction with respect to a reduction in surgical and healing time without increasing complication rates. CLINICAL RELEVANCE: Highly comminuted long-bone fractures can be successfully repaired using an IN without reconstructing the fracture fragments in dogs.

Animals↗

Assessing the efficacy of perioperative oral carprofen after cranial cruciate surgery using noninvasive, objective pressure platform gait analysis.

OBJECTIVE: To document, using pressure platform gait analysis, the effect of perioperative oral carprofen on limb function and pain after cranial cruciate ligament surgery in dogs. STUDY DESIGN: Blinded, prospective clinical investigation. ANIMALS: Twenty dogs with naturally occurring unilateral cranial cruciate disease. PROCEDURE: Physiologic indices, subjective pain scoring, and pressure platform gait analyses were performed before and 24, 48, and 72 hours after surgery. Correlations were assessed between methods of evaluation and the data was compared across treatment groups. RESULTS: No strong correlations were noted between physiologic data, subjective scoring systems, or gait analysis data at a walk or stance. Although average measures of limb function were nearly twice as large in dogs treated with carprofen, no significant differences between groups over time were identified. No significant differences were noted in any other measure of pain or limb function. Power analysis of peak vertical force at a walk indicated that significant difference would have been detected had the number of dogs in each group been increased to 35. CONCLUSION: When limb function was assessed with pressure platform gait analysis no statistical difference was noted between groups with respect to PVF and VI at a walk or stance, although average ground reaction forces for dogs in the carprofen group were greater than the traditional pain management group at all time points. CLINICAL RELEVANCE: Oral carprofen appears to provide some benefit for the treatment of postoperative orthopedic pain.

Administration, Oral↗