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Biomedical subjects

Michael Grover

Publications and source records attributed to Michael Grover.

6 recordsLinked to original sources
PubMed2006

How should patients with Barrett's esophagus be monitored?

Some patients who have been diagnosed with Barrett's esophagus will develop dysplasia and, in some cases, esophageal carcinoma (strength of recommendation [SOR]: A, based on consistent cohort studies). Endoscopic surveillance is recommended for all patients with Barrett's esophagus as it is superior to other methods for detecting esophageal cancer (SOR: B, based on systematic review). The degree of dysplasia noted on biopsy specimens correlates with the risk of esophageal carcinoma development and should guide the frequency of subsequent evaluations (SOR: B, based on consistent cohort studies). The optimal frequency of endoscopy has yet to be determined in any randomized trial. Recommendations from the 2002 American College of Gastroenterology (ACG) Practice Guideline provide guidance as to the frequency of endoscopy surveillance but were not based on an explicit systematic review of the literature (SOR: C, based on expert opinion).

Adenocarcinoma↗
PubMed2006

Clinical inquiries. Should patients receive 23-valent pneumococcal vaccination more than once?

No patient-oriented evidence supports pneumococcal revaccination of any patient (high-risk or otherwise). Antibody levels may be augmented by revaccination; however, the clinical efficacy of revaccination, even among high-risk patients, is unknown. Revaccination is recommended by the Advisory Committee on Immunization Practices (ACIP) in certain circumstances (strength of recommendation [SOR]: C, expert opinion based on physiology/bench research). Revaccination once appears to be safe, especially if provided 5 years or more after primary vaccination (SOR: B, based upon consistent results of cohort studies and nonrandomized prospective trials).

Clinical Trials as Topic↗
PubMed2004

Forecasting changes in physician services per capita in Minnesota through 2030.

As the population ages and the ratio of retirees increases, the likely supply of physicians and physician services over the next few decades is being closely scrutinized. In this article, we use simple regression models to predict the supply of physicians and physician-hours per capita in Minnesota through the year 2030. We present the results from two models. The first uses data on all practicing physicians in the years 1995 to 2000 and projections for the entire population. The second "adjusted" model uses data on physicians who were younger than 65 in the years 1995 to 2000 and projections for the population 65 and older. The adjusted model represents a "worst case scenario" that removes physicians who typically work fewer hours from the count of physicians and retains the population needing the most health care services.

Forecasting↗