Biomedical subjects

Michelle R Molis

Publications and source records attributed to Michelle R Molis.

6 recordsLinked to original sources

PubMed2005

Perception of dissonance by people with normal hearing and sensorineural hearing loss.

The purpose of this study was to determine whether the perceived sensory dissonance of pairs of pure tones (PT dyads) or pairs of harmonic complex tones (HC dyads) is altered due to sensorineural hearing loss. Four normal-hearing (NH) and four hearing-impaired (HI) listeners judged the sensory dissonance of PT dyads geometrically centered at 500 and 2000 Hz, and of HC dyads with fundamental frequencies geometrically centered at 500 Hz. The frequency separation of the members of the dyads varied from 0 Hz to just over an octave. In addition, frequency selectivity was assessed at 500 and 2000 Hz for each listener. Maximum dissonance was perceived at frequency separations smaller than the auditory filter bandwidth for both groups of listners, but maximum dissonance for HI listeners occurred at a greater proportion of their bandwidths at 500 Hz than at 2000 Hz. Further, their auditory filter bandwidths at 500 Hz were significantly wider than those of the NH listeners. For both the PT and HC dyads, curves displaying dissonance as a function of frequency separation were more compressed for the HI listeners, possibly reflecting less contrast between their perceptions of consonance and dissonance compared with the NH listeners.

Acoustic Stimulation↗

PubMed2005

Evaluating models of vowel perception.

There is a long-standing debate concerning the efficacy of formant-based versus whole spectrum models of vowel perception. Categorization data for a set of synthetic steady-state vowels were used to evaluate both types of models. The models tested included various combinations of formant frequencies and amplitudes, principal components derived from excitation patterns, and perceptually scaled LPC cepstral coefficients. The stimuli were 54 five-formant synthesized vowels that had a common F1 frequency and varied orthogonally in F2 and F3 frequency. Twelve speakers of American English categorized the stimuli as the vowels /I/, /[symbol: see text]/, or /[symbol: see text]/. Results indicate that formant frequencies provided the best account of the data only if nonlinear terms, in the form of squares and cross products of the formant values, were also included in the analysis. The excitation pattern principal components also produced reasonably accurate fits to the data. Although a wish to use the lowest-dimensional representation would dictate that formant frequencies are the most appropriate vowel description, the relative success of richer, more flexible, and more neurophysiologically plausible whole spectrum representations suggests that they may be preferred for understanding human vowel perception.

Acoustic Stimulation↗

PubMed2004

Speech recognition in fluctuating and continuous maskers: effects of hearing loss and presentation level.

Listeners with normal-hearing sensitivity recognize speech more accurately in the presence of fluctuating background sounds, such as a single competing voice, than in unmodulated noise at the same overall level. These performance differences are greatly reduced in listeners with hearing impairment, who generally receive little benefit from fluctuations in masker envelopes. If this lack of benefit is entirely due to elevated quiet thresholds and the resulting inaudibility of low-amplitude portions of signal + masker, then listeners with hearing impairment should derive increasing benefit from masker fluctuations as presentation levels increase. Listeners with normal-hearing (NH) sensitivity and listeners with hearing impairment (HI) were tested for sentence recognition at moderate and high presentation levels in competing speech-shaped noise, in competing speech by a single talker, and in competing time-reversed speech by the same talker. NH listeners showed more accurate recognition at moderate than at high presentation levels and better performance in fluctuating maskers than in unmodulated noise. For these listeners, modulated versus unmodulated performance differences tended to decrease at high presentation levels. Listeners with HI, as a group, showed performance that was more similar across maskers and presentation levels. Considered individually, only 2 out of 6 listeners with HI showed better overall performance and increasing benefit from masker fluctuations as presentation level increased. These results suggest that audibility alone does not completely account for the group differences in performance with fluctuating maskers; suprathreshold processing differences between groups also appear to play an important role. Competing speech frequently provided more effective masking than time-reversed speech containing temporal fluctuations of equal magnitude. This finding is consistent with "informational" masking resulting from competitive processing of words and phrases within the speech masker that would notoccur for time-reversed sentences.

Acoustic Stimulation↗

PubMed2004

The effect of onset asynchrony on profile analysis by normal-hearing and hearing-impaired listeners.

The effect of onset asynchrony on discrimination of spectral shape was evaluated for hearing-impaired and normal-hearing listeners. Stimuli were the sum of four tones equally spaced on a logarithmic frequency scale. The standard stimulus had tones of equal amplitude, and the signal stimulus had two adjacent components increased in level, and the other two components decreased in level. Thresholds for discrimination between the standard and signal stimuli were measured as a function of an onset asynchrony among the components of 0, 50, and 200 ms. Hearing-impaired and normal-hearing listeners had similar thresholds when the stimulus components were widely spaced in frequency, but hearing-impaired listeners had much higher thresholds for narrowly spaced components. Excitation pattern analyses indicated that listeners may use spectral peaks in the stimulus rather than the change in excitation across the full stimulus bandwidth for spectral shape discrimination tasks. Increasing temporal asynchrony of components resulted in increased thresholds for both groups of listeners to a greater extent in the wide span than the narrow span. Reduced effects of onset asynchrony in the narrow span suggest that spectral resolvability of components plays an important role in the processing of onset asynchrony across frequency.

Acoustic Stimulation↗

PubMed2003

Identifying dead regions in the cochlea: psychophysical tuning curves and tone detection in threshold-equalizing noise.

OBJECTIVE: Recent studies indicate that high-frequency amplification may provide little benefit for listeners with moderate-to-severe high-frequency hearing loss, and may even reduce speech recognition. Moore and colleagues have proposed a direct link between this lack of benefit and the presence of regions of nonfunctioning inner hair cells (dead regions) in the basal cochlea and have suggested that psychophysical tuning curves (PTCs) and tone detection thresholds in threshold-equalizing noise (TEN) are psychoacoustic measures that allow detection of dead regions ([Moore, Huss, Vickers, Glasberg, & Alcántara, 2000]; [Vickers, Moore, & Baer, 2001]). The experiments reported here examine the consistency of TEN and PTC tasks in identifying dead regions in listeners with high-frequency hearing loss. DESIGN: Seventeen listeners (18 ears) with steeply sloping moderate-to-severe high-frequency hearing loss were tested in PTC and TEN tasks intended to identify ears with high-frequency dead regions. In the PTC task, pure-tone signals of fixed level were masked by narrowband noise that slowly increased in center frequency. For a range of signal frequencies, noise levels at masked threshold were determined as a function of masker frequency. In the TEN task, masked thresholds for pure-tone signals were determined for a fixed-level, 70 dB/ERB TEN masker (for some listeners, 85 or 90 dB/ERB TEN was also tested at selected probe frequencies). RESULTS: TEN and PTC results agreed on the presence or absence of dead regions at all tested frequencies in 10 of 18 cases (approximately 56% agreement rate). Six ears showed results consistent with either mid- or high-frequency dead regions in both tasks, and four ears did not show evidence of dead regions in either task. In eight ears, the TEN and PTC tasks produced conflicting results at one or more frequencies. In instances where the TEN and PTC results disagreed, the TEN results suggested the presence of dead regions whereas the PTC results did not. CONCLUSIONS: The 56% agreement rate between the TEN and PTC tasks indicates that at least one of these tasks was only partially reliable as a diagnostic tool. Factors unrelated to the presence of dead regions may contribute to excess masking in TEN without producing tip shifts in PTCs. Thus it may be appropriate to view tuning curve results as more reliable in cases where TEN and PTC results disagree. The current results do not provide support for the TEN task as a reliable diagnostic tool for identification of dead regions.

Aged↗

PubMed2002

Generalizing a neuropsychological model of visual categorization to auditory categorization of vowels.

Twelve male listeners categorized 54 synthetic vowel stimuli that varied in second and third formant frequency on a Bark scale into the American English vowel categories [see text]. A neuropsychologically plausible model of categorization in the visual domain, the Striatal Pattern Classifier (SPC; Ashby & Waldron, 1999), is generalized to the auditory domain and applied separately to the data from each observer. Performance of the SPC is compared with that of the successful Normal A Posteriori Probability model (NAPP; Nearey, 1990; Nearey & Hogan, 1986) of auditory categorization. A version of the SPC that assumed piece-wise linear response region partitions provided a better account of the data than the SPC that assumed linear partitions, and was indistinguishable from a version that assumed quadratic response region partitions. A version of the NAPP model that assumed nonlinear response regions was superior to the NAPP model with linear partitions. The best fitting SPC provided a good account of each observer's data but was outperformed by the best fitting NAPP model. Implications for bridging the gap between the domains of visual and auditory categorization are discussed.

Adolescent↗