Biomedical subjects

Mikhail Benet Rodríguez

Publications and source records attributed to Mikhail Benet Rodríguez.

3 recordsLinked to original sources

PubMed2004

[Cardiovascular hyperactivity in patients with family history of high blood pressure].

BACKGROUND AND OBJECTIVE: The association between family history of essential high blood pressure (FH of HBP) and the cardiovascular hyperactivity to the isometric exercise is not well known; that is why the aim of this study was to describe this relation and to determine whether it is independent of the presence of cardiovascular risk factors. PATIENTS AND METHOD: We carried out a correlational descriptive study with a sample of 1855 people of both sexes between 18 and 70 years of age. The cardiovascular hyperactivity, expression of the cardiovascular response to the activity of the sympathetic nervous system (SNS), was determined by means of the test of the sustained weight (TSW). Comparisons of the values of cardiovascular reactivity were developed between individuals with and without FH of HBP and a model of logistical regression. The level of statistical significance was 95%. RESULTS: The arterial blood pressure at the end of the TSW was higher in individuals with FH of HBP independently of the age group. The cardiovascular hyperactivity, measured by means of they systolic index of cardiovascular reactivity, was also significantly higher in subjects with FH of HBP. Finally, individuals with FH of HBP showed a higher risk (more than 5 times) of having cardiovascular hyperactivity (OR = 5.16; CI 95%, 3.51-7.59), this association being independent of other cardiovascular factors of risk. CONCLUSIONS: The FH of HBP is independently related to the cardiovascular hyperactivity, to the isometric exercise, of other cardiovascular risks factors. These elements help explain the relationship between cardiovascular hyperactivity, the activity of SNS and essential high blood pressure, at least in an important group of people.

Adolescent↗

PubMed2002

[Hormonal replacement therapy in Spain].

BACKGROUND: The consumption of hormonal replacement therapy (HRT) in Spain is not known. Therefore, we have conducted a study to know the mean features of that consumption and to find out the prevalence of use among women older than 40. SUBJECTS AND METHOD: To know the consumption, we have used the information contained in ECOM database from the Ministry of Health regarding medicines sold to the Spanish Health System. Also, data gathered by the General Practitioner Sentinel Network of Castilla y León had been used. The data of consumption are presented in daily defined dose per 1000 women more than 40 years (DHD); prevalence of use per year and for ages was also estimated. RESULTS: The HRT consumption in Spain throughout the National Health System was 6,94 DHD in 1989 and 39.92 DHD in 1999. The percentage of women using this therapy was 0.7% in 1989 and 3,4 in 1999; the group 50-54 years had the highest prevalence of use, 10,84% (IC 95%, 10.66-11.01). CONCLUSIONS: The release into the market of those transdermal forms of HRT facilitated an increase in the consumption. Nonetheless, the proportion of postmenopausal women on HRT in Spain is lower than that of the other countries from the European Union. The proportion of women treated with estrogens and progestins is also small compared with current recommendations.

Adult↗

PubMedDate not supplied

[Cardiovascular reactivity and cardiovascular risk factors in normotensive individuals of less than 40 years of age].

BACKGROUND: Cardiovascular hyperactivity has been found to be related to cardiovascular risk factors among the population as a whole. Knowing whether these factors are also related to the population of individuals under age 40 could be important for modifying lifestyles and for taking action to prevent cardiovascular diseases. METHODS: A representative comparative study was made out of 249 individuals with normal blood pressure, of both sexes, within the 18-40 age range. These individuals were divided into two groups based on the results of the hand-held weight test (HHWT), this test take into account the use of an isometric exercise to achieve cardiovascular reactivity. One of the groups was composed of individuals with cardiovascular hyperreactivity (n = 62), with blood pressure (BP) values of equal or higher 90/140 mmHg following the hand-held weight test, the other group was composed of individuals with normal cardiovascular reactivity (n = 187), with blood pressure values less 90/140 mmHg. Using a logic regression model, the relationship was determined by age, sex, family history of FH of HBP), physical activity (PhysAct), cigarette-smoking (CS), alcoholic beverage intake (ABI), salt intake (SI) and race with the condition of cardiovascular hyperreactivity. RESULTS: The risk of having cardiovascular hyperreactivity was double for those individuals who had a family history of high blood pressure (OR = 2.88 IC 95%: 1.54-5.36). For every year of age, the risk of hyperreactivity increased 1.08 times, having increased up to 1.14 times. On the other hand, the body mass index revealed a significant relationship independent of the condition of vascular hyperreactivity (OR = 1.11 IC 95%: 1.01-1.21). None of the other variables studies showed any relationship to the condition of cardiovascular hyperreactivity. CONCLUSIONS: Individuals within the 18-40 age range who have normal blood pressure, have a higher risk of cardiovascular reactivity if they have a family history of high blood pressure, if their body mass index increases and with the age increment.

Adolescent↗