Biomedical subjects

Milind J Kothari

Publications and source records attributed to Milind J Kothari.

7 recordsLinked to original sources

PubMed2005

Mononeuritis multiplex secondary to sarcoidosis.

Peripheral nerve involvement is a rare, yet treatable neurological manifestation of sarcoidosis. Most patients respond well to corticosteroids, but relapses are common and the long-term prognosis remains unpredictable. We present a patient with an asymmetrical neurological presentation of previously undiagnosed sarcoidosis. She presented with paresthesias and predominantly distal extremity weakness. Other possible causes of neuropathy were ruled out and she was found to have an elevated serum ACE level. A nerve/lip biopsy demonstrated non-caseating granulomas consistent with sarcoid. Her clinical outcome was favorable after initiating treatment with high dose oral prednisone.

Female↗

PubMed2005

Hereditary neuropathies.

Hereditary neuropathies represent a clinically diverse group of disorders. Patients can present in a variety of ways-most typically, with slowly progressive distal and symmetric muscle weakness, atrophy, and sensory loss. This article outlines the basic clinical and electrodiagnostic characteristics, pathophysiology, genetics, and diagnostic approach to these conditions.

Education, Medical, Continuing↗

PubMed2005

Evaluating the patient with peripheral nervous system complaints.

Patients commonly seek care from their family physicians for symptoms that are suggestive of peripheral nervous system (PNS) dysfunction. At some point in active practice, virtually all family physicians will be required to conduct at least an initial evaluation of a patient with PNS. The authors outline and describe common themes found in the symptoms and diagnoses of PNS dysfunctions. These themes may be useful to physicians when performing initial evaluations of patients with PNS dysfunctions. The authors also discuss diagnostic methods and effective therapeutic interventions for this population.

Algorithms↗

PubMed2004

The neurologic assessment and treatment of the "difficult to extubate" patient.

Neurologic issues are involved in the patient who is difficult to wean. Assessing the patient and performing a complete neurologic examination are important when developing a successful weaning strategy. The neurologist contributes to this process by providing expertise in the various neurologic conditions and skill in performing a thorough neurologic examination.

Brain Diseases↗

PubMed2004

Myasthenia gravis.

Myasthenia gravis (MG) is a chronic neuromuscular disorder that can lead to various degrees of neurologic dysfunction. Initial patient presentation may be a diagnostic dilemma to the family physician unfamiliar with testing methods for and the treatment and care of patients with MG. The author focuses on the clinical features, electrodiagnostic testing, and treatment of patients with MG.

Cholinesterase Inhibitors↗

PubMed2002

Use of intravenous immunoglobulin in Lambert-Eaton myasthenic syndrome.

The authors report a case of a 65-year-old woman with small cell lung cancer who had profound, progressive lower extremity weakness, intermittent blurred vision, a dry mouth, and orthostatic hypotension. Results of laboratory and electrodiagnostic studies were consistent with the diagnosis of Lambert-Eaton myasthenic syndrome. The patient was treated with one course of intravenous immunoglobulin and had significant improvement.

Action Potentials↗

PubMedDate not supplied

Bilateral anterior interosseous neuropathy following surgery: a case report.

The authors present a patient who developed bilateral anterior interosseous neuropathy following an abdominal surgical procedure. This case is of particular interest because while anterior interosseous nerve involvement may be seen with Parsonage-Turner Syndrome, the bilateral involvement is quite rare. The electrodiagnostic findings are presented and the literature reviewed.

Brachial Plexus Neuritis↗