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Biomedical subjects

Mingli Zhang

Publications and source records attributed to Mingli Zhang.

5 recordsLinked to original sources

Wave-front analysis method of circular aperture sampling for collimation testing.

A new type of wave-front analysis method for the collimation testing of laser beams is proposed. A concept of wave-front height is defined, and, on this basis, the wave-front analysis method of circular aperture sampling is introduced. The wave-front height of the tested noncollimated wave can be estimated from the distance between two identical fiducial diffraction planes of the sampled wave, and then the divergence is determined. The design is detailed, and the experiment is demonstrated. The principle and experiment results of the method are presented. Owing to the simplicity of the method and its low cost, it is a promising method for checking the collimation of a laser beam with a large divergence.

Journal Article↗

[Comparison and correlative analysis of pulmonary function markers after extracorporeal circulation].

OBJECTIVE: To compare the clinic significance of three lung function markers after cardiopulmonary bypass operation. METHODS: Twenty-four patients who continuously took selective coronary artery bypass grafting (CABG) with cardiopulmonary bypass in our hospital were separated randomly to AT group and non AT group according the different treatments of the residue blood in extracorporeal circulation (ECC) circuit, 12 patients in each group. The data of hemodynamics and oxygenation after anesthesia induction and 1, 6, 24, 48 h after ECC were recorded. Respiratory index (RI), oxygenation index (OI) and M index (PaO2/PAO2) were counted and compared at the same time. RESULTS: CI, O2ER, DO2I and VO2I were all elevated obviously after ECC, and Qs/Qt were decreased. There were no difference of all these markers between two groups. RI, OI and PaO2/PAO2 did not change during perioperation in AT group, but in non AT group, RI was increased after ECC, company with the decrease of OI and PaO2/PAO2 at the same time. Nevertheless there was no difference between two groups. But the alterations of the marker percentages were more obviously, there were marked differences between the percentages of RI and PaO2/PAO2 24 h after ECC. All three markers had correlation with Qs/Qt and VO2I. CONCLUSION: RI, OI and PaO2/PAO2 all can reflect appropriately the change of lung function after extracorporeal circulation and the monitor of the developmental alterations individually may be more instructive in clinical practice.

Cardiopulmonary Bypass↗

[Intraoperative autotransfusion with HDCS-2 blood recovery-therapy instrument].

OBJECTIVE: To evaluation the clinic effects of intraoperative autotransfusion with the blood recovery-therapy instrument. METHODS: Intraoperative autotransfusion with the blood recovery-therapy instrument was performed in 116 operations from Aug 2000 to Nov 2001. The hemocytology, the markers of liver and renal function, blood coagulation and the total amount of drain after operation were analyzed. RESULTS: The autotransfusions were all successful. The levels of HCT, RBC, Hb in processed blood were significantly higher than in the recovered blood, while the PLT was much lower than in the recovered blood. The temperature tendency after intraoperative autotransfusion was in coincidence with the law of reaction after normal operation. The levels of RBC, Hb, WBC and HCT decreased one day and one week after operation compared with those before operation. Although the level of PLT decreased one day after operation, it recovered one week after operation. The levels of ALT, AST, total protein(TP) and BUN were markedly lower in processed blood than in recovered blood. TP was decreased one day after operation, but restored one week after operation. The other markers of liver and renal function did not change during the peri-operation. The clearance to heparin of the process was (96 +/- 0.6)%. ACT and total amount of drain after operation did not alter obviously. CONCLUSION: Practice of intraoperative autotransfusion with the blood recovery-therapy instrument can reduce the demand of allogenic blood effectually, and the occurrence of complications after operation.

Adolescent↗

[Circulation assist in the radical operation of retro-peritoneal malignancy with the inferior vena cava thrombotic involvement].

OBJECTIVE: To discuss the key role of various mode of circulation assist in the radical operation of retro-peritoneal malignancy with the inferior vena cava thrombotic involvement. METHODS: >From the June 1999 to the March 2001, 6 patients with retro-peritoneal malignancy with thrombosis involving the inferior vena cava, were completely resected with various mode of circulation assist. RESULTS: All the patients operated have good outcomes and follow-up (1 - 20 months) except one death 1 month after operation. CONCLUSION: According to the various types of tumor thrombi, individualized and technically feasible circulation assist mode should be utilized to achieve the satisfactory outcomes.

Aged↗

[Studies on xenogenic acellular dermal matrix as a filling material].

OBJECTIVE: To explore the biological reaction of swine acellular dermal matrix as a filling material for body surface deformity. METHODS: Xenogenic acellular dermal matrix was implanted into the hypoderm of rabbits. The implants were measured and observed with pathological and transmission electron microscopic technique at regular times. The results were compared with implantation of autologous dermis and swine dermis. RESULTS: The implanted xenogenic acellular dermal matrix and autologous dermis had slight inflammatory reaction. At 2 weeks there were fibroblasts and capillaries in the implants. The absorptivity of the xenogenic acellular dermal matrix was lower than the swine dermis. The xenogenic acellular dermal matrix was used in 2 clinical cases and obtained good result. CONCLUSION: The xenogenic acellular dermal matrix is an ideal material with good compatibility feature and low absorptivity.

Animals↗