Biomedical subjects

Miyong T Kim

Publications and source records attributed to Miyong T Kim.

At least 19 recordsLinked to original sources

PubMed2007

Barriers to and strategies for recruiting Korean Americans for community-partnered health promotion research.

While increasing numbers of researchers are targeting ethnic minorities in order to address their health disparities, the unique health needs of Korean Americans are not well known to the mainstream community, and only relatively few systematic research studies have been conducted in this "hard-to reach" population. The purpose of this paper is to describe the barriers to recruiting participants for health promotion research and to identify facilitators in the community that can contribute to this effort. We have analyzed data pertaining to the 14 studies we have conducted since 1998, which included a total sample of about 2,400 Korean Americans. We describe in detail the unique recruitment challenges that we have faced in regard to the culture, language, sociodemographic characteristics of the participants, such as gender and age, and other community level barriers. Multiple strategies at different levels (individual and community) to address these issues are discussed.

Adolescent↗

PubMed2006

Cigarette smoking, elevated fasting serum glucose, and risk of pancreatic cancer in Korean men.

Pancreatic cancer is one of the most fatal human cancers and continues to be a major unsolved health problem. The goal of this study was to estimate the independent effects and interactions between cigarette smoking and diabetes on the risk of pancreatic cancer in Korean male population. Cigarette smoking and the risk of incidence and death from pancreatic cancer were examined in a 10-year prospective cohort study of 446,407 Korean men aged 40 to 65 years who received health insurance from the National Health Insurance Corporation and who had a medical evaluation in 1992. Relative risks (RR) and 95% confidence intervals (CI) were calculated using a Cox proportional hazards model after adjusting for age, body mass index, exercise and alcohol use. Current smoking was associated with an increased risk of incidence (RR = 1.7, 95% CI = 1.6-1.9) and mortality (RR = 1.6, 95% CI = 1.4-1.7) from pancreatic cancer. The RR for pancreatic cancer increased with both duration and amount of smoking. Diabetes was also associated with an increased risk of both incidence (RR = 1.8, 95% CI = 1.5-2.2) and mortality (RR = 1.7, 95% CI = 1.4-2.1) from pancreatic cancer. There was no interaction between smoking and fasting serum glucose in terms of pancreatic cancer risk. Thus, our prospective study has demonstrated that cigarette smoking and elevated fasting serum glucose are independently associated with an increased risk of pancreatic cancer in a large cohort of Korean males.

Adult↗

PubMed2006

Predictors of psychological well-being amongst Korean immigrants to the United States: a structured interview survey.

BACKGROUND: As international migration becomes a common phenomenon in many countries, the health issues of immigrants are becoming an important area of concern among health care professionals worldwide. OBJECTIVE: Adopting the stress-health outcome framework, this study examined risks and resources of both positive and negative affect (i.e., happiness and depression) among Korean Americans who experienced acculturative and recent life stresses. METHODS: Hierarchical multiple regression analyses were performed to examine correlates of positive and negative outcomes in the stress process on a final sample of 147 Korean immigrants from a cross-sectional study. RESULTS: For happiness, lower levels of acculturative stress and recent life stress, a greater sense of mastery, and greater social support were associated with an increased level of happiness. None of the individual characteristics were significant. R(2) for the full model was .53. For negative affect, acculturative stress and recent life stress explained a significant portion (41%) of the total variance associated with depression (R(2)=.51). As with the happiness variable, individual characteristics failed to add to the predictiveness of the equation, while sense of mastery and social support functioned as significant resources in reducing depression. CONCLUSION: Increased mastery and greater social support were consistently predictive of greater happiness and less depression. Implications for future immigrant research are discussed.

Acculturation↗

PubMed2006

Assessing risk factors of coronary heart disease and its risk prediction among Korean adults: the 2001 Korea National Health and Nutrition Examination Survey.

BACKGROUND: An in-depth assessment of coronary heart disease (CHD) risk factors in Koreans was conducted to develop effective risk reduction strategies for this population. METHOD: Based on 2001 Korea National Health and Examination Survey, a cross-sectional survey, this paper presents the prevalence of major CHD risk factors and estimates future risk by applying the Framingham model and CHD risk factor guidelines of the National Cholesterol Education Program Adult Treatment Panel III (NCEP) to 4639 Koreans aged 20 to 79 years. RESULT: Our findings indicate that CHD is a major health threat to Koreans. Among these factors, low high-density lipoprotein cholesterol (HDL-C) was seen in 35.1% of men and 17.8% of women; both had a low rate of controlled high blood pressure (men 13.7%, women 23.6%), and age-adjusted current smoking was especially high (61.6%) in men. The 10-year CHD risk averaged 11.1% in men and 5.5% in women based on Framingham model, and 7.4% and 1.4% based on NCEP guidelines. About 9.1% of men and 2.6% of women were "high-risk," (>20%) based on the Framingham model, and 4.7% and 0.7%, respectively, on the NCEP guideline. Diabetes was the most prevalent risk factor among high-risk individuals and total cholesterol in men and low HDL-C in women was fairly high regardless of prediction method. CONCLUSION: These findings suggest that current coronary heart health of Koreans is nearly comparable to that of western developed countries. Developing and implementing effective population-based intervention strategies focusing on diabetes is warranted to lower the CHD risk for Koreans.

Adult↗

PubMed2006

Effects of stressful life events in young black men with high blood pressure.

OBJECTIVES: 1) To describe stressful life events as experienced by a sample of young Black men with high blood pressure (HBP) living in inner-city Baltimore, Maryland; and 2) to examine the effect of cumulative stressful life events on substance use, depression, and quality of life. METHODS: Data were obtained over 48 months by interview from 210 men in an HBP management study. RESULTS: Stressors repeatedly occurring over time included death of family member or close friend (65.2%), having a new family member (32.9%), change in residence (31.4%), difficulty finding a job (24.3%), and fired or laid off from work (17.6%). Involvement with crime or legal matters was reported at least twice during the 48 months by 33.3% of men. When a cumulative stressful life events score was calculated by summing the number of events experienced at 6-month points over 48 months and tested for its relationship with the health outcomes, the findings of multivariate analyses revealed significant associations between cumulative life stressors and depression and quality of life. No significant relationship was found between stressful life events and substance use. CONCLUSIONS: The results suggest that cumulative stressful life events have a negative effect on mental health and quality of life in young Black men with HBP. Future study should focus on developing interventions to assist individuals in managing distress related to stressful events with necessary community resources.

Adolescent↗

PubMed2006

Barriers to care and control of high blood pressure in Korean-American elderly.

OBJECTIVES: To identify barriers to achieving optimal management of high blood pressure (HBP) among hypertensive Korean-American elderly (KAE). METHODS: This study used data on a subsample of 146 hypertensive KAE from a total of 205 KAE in Maryland who participated in a cardiovascular health assessment study. The study group consisted of 56 males and 90 females with a mean age of 69.8 +/- 6.6 years. The PRECEDE-PROCEED model guided selection of study variables. RESULTS: Many KAE with HBP had no regular HBP care (66%) and did not achieve HBP control (92.5% of KAE with HBP and 77.6% of KAE on HBP medications). Lack of health insurance emerged as a strong barrier to receiving adequate HBP care. Other barriers to HBP care included not having a Korean doctor and not having a regular medical checkup. While 22.4% of KAE on HBP medication had controlled blood pressure (BP), those with more visits to traditional Asian medicine doctors were less likely to have achieved HBP control. CONCLUSIONS: The study unveils some of the multilevel barriers to care and control of HBP uniquely experienced by KAE and suggests the need for developing interventions to assist KAE in managing HBP.

Aged↗

PubMed2005

Factors associated with depression experience of immigrant populations: a study of Korean immigrants.

A correlational, cross-sectional study with multivariate analysis was conducted to identify factors that influence the depression experience in 154 Korean immigrants. Based on the stress-health outcome framework, four variables (i.e., sense of mastery, socioeconomic status, social support, and acculturation) were tested for their mediating effects between stress and depression experienced by Korean Americans. Path analyses showed that the negative effect of life stress on depression was buffered by higher levels of sense of mastery and social support in the Korean sample. Implications for future cross-cultural depression research and preventive strategies against depression in immigrant populations are discussed.

Adult↗

PubMed2005

Does long-term lactation protect premenopausal women against hypertension risk? A Korean women's cohort study.

BACKGROUND: Little is known about the long-term effect of lactation on maternal cardiovascular health except for a few animal or human experimental studies. The objective of this study was to examine the effects of lactation on the incidence of hypertension in premenopausal women. METHODS: The data were derived from a cohort study with 6 years follow-up (1995-2000). The cohort was composed of 177,749 Korean premenopausal women, aged 20-59, who had medical evaluations in 1992 and 1994. During the follow-up, blood pressure was measured as part of the 1996, 1998, and 2000 periodic examinations. RESULTS: In multivariate Cox proportional hazard models, lactation decreased the risk of hypertension (risk ratio, 0.92; 95% confidence interval, 0.90-0.96). Compared with women who with no history of lactation, 1-6 months of lactation decreased the risk of hypertension (RR, 0.90; 95% CI, 0.87-0.93), as did 7-12 months (RR, 0.92; 95% CI, 0.87-0.98) or 13-18 months (RR, 0.93; 95% CI, 0.86-0.99). In particular, the coexistence of obesity and no lactation increased the risk of hypertension (P for interaction = 0.028). CONCLUSION: This finding suggests that lactation may be a protective factor against hypertension among premenopausal women.

Adult↗

PubMed2004

Serum uric acid and risk of death from cancer, cardiovascular disease or all causes in men.

OBJECTIVE: Although many epidemiological studies have suggested that increased serum uric acid levels are a risk factor for mortality, this relationship remains uncertain. This cohort study examined the effects of serum uric acid level on death from cancer, atherosclerotic cardiovascular disease (ASCVD) or all causes in men. METHOD: A 9-year, prospective cohort study was carried out with 22698 Korean men, aged 30 to 77 years, who received health insurance from the National Health Insurance Corporation and who underwent biennial, secondary medical evaluations in 1992-1996. The main outcome measures were death from cancer, ASCVD or all causes, compared by quintiles of serum uric acid level. At baseline, the mean (SD) level of serum uric acid was 354.4 (98.1) micromol/l. RESULTS: During 199746 person-years of follow-up, there were 387 cancer deaths, 323 ASCVD (99 ischaemic heart disease, 192 stroke) deaths and 1625 all-cause deaths. In multivariate Cox proportional hazards models, having controlled for age, current smoking, diabetes, hypertension and hypercholesterolaemia, uric acid levels were not associated with mortality from cancer, ASCVD or all causes. However, for those with diabetes, uric acid levels were associated with mortality from all causes even after full adjustment of the covariates. When the interaction term was included in the multivariate model, there was significant interactive effect of uric acid with diabetes (RR=1.26, 95% confidence interval 1.02-1.55) on the risk of all cause of death, whereas the effects of uric acid itself did not attain significance. CONCLUSION: These findings indicate that uric acid level is not an independent risk factor for death from cancer, ASCVD or all causes.

Adult↗

PubMed2004

Cardiovascular risks in a military health care beneficiary population with high blood pressure.

Prevention strategies for coronary artery disease among hypertensive patients require assessment of other modifiable risk factors in the target population. In this article, we describe the prevalence of other cardiovascular risk factors in military beneficiaries with high blood pressure (HBP). Baseline data from an ongoing randomized clinical trial designed to test effectiveness of a comprehensive HBP intervention are used in the analysis. A total of 147 beneficiaries from a military health system participated in this study. Findings indicate that the rate of HBP control in this sample was suboptimal (32%: blood pressure < 140/90). Other prevalent cardiovascular risk factors include high cholesterol, obesity, and diabetes. Many of these patients (31.3%) are also in the moderate-to-high danger level of developing coronary artery disease in the near future. These findings warrant a regular assessment of cardiovascular risk factors and rigorous behavioral interventions for all beneficiaries of the military health care system.

Adult↗

PubMed2003

Effect of lifetime lactation on breast cancer risk: a Korean women's cohort study.

The objective of our study was to examine the effect of lifetime lactation on breast cancer risk among premenopausal women. The data were from a prospective cohort study with a follow-up period of 6 years in Korea (1995-2000). The cohort was composed of 110,604 premenopausal parous Korean women, aged 20 years and older, who received health insurance from the Korea Medical Insurance Corporation and who had medical evaluations in 1992 and 1994. Multivariate Cox proportional hazard models were tested, controlling for age, age at menarche, number of children, age at first pregnancy, oral contraceptive use, smoking, exercise and obesity. At baseline, 57,440 (51.9%) reported breastfeeding and 4,584 (4.1%) reported breastfeeding more than 24 months. From 1995-2000, 360 incident cases of breast cancer (61.8/100,000 person-years) occurred. Compared to parous women who had no history of lactation, a period of lactation of 13-24 months decreased the risk of breast cancer (RR, 0.7; 95% CI, 0.5-1.1), and this risk was decreased even further for those who breastfed for more than 24 months (RR, 0.6; 95% CI, 0.3-1.0). There was a clear trend of decreasing breast cancer risk with the duration of lactation (p for trend <0.001). In conclusion, our study of a large Korean cohort provides additional empirical evidence to current theoretical conjecture that lactation decreases the risk of breast cancer among premenopausal women.

Adult↗

PubMed2003

Validity of self-report of illicit drug use in young hypertensive urban African American males.

UNLABELLED: Inaccurate self-reporting is the primary threat to the validity and utility of self-report in the research on illicit drug use. The purpose of this study was to estimate the sensitivity and specificity of self-report of drug use, using urine toxicity screening as a criterion variable, and to explore the individual characteristics associated with false reporting in a sample of urban African American males. Baseline data from urine tests and a questionnaire about self-report of illicit drug use were obtained from 290 hypertensive African American males enrolled in an ongoing hypertension clinical trial. Sensitivity and specificity of self-report were estimated, and multivariate logistic regression analysis was conducted to examine factors associated with true or false reporting of drug use. RESULT: The sensitivity and specificity of self-report were 0.87+/-0.019 and 0.63+/-0.02, respectively. Members of the underreporting group were more likely to be older, more educated, employed, living with family, and having experience with jail. Jail experience (OR, 2.0) and living with friends or family (OR, 1.7) were the two strongest predictors of false reporting. This study further confirms that social desirability and fear of the consequences of drug use are major contributing factors in underreporting of drug use.

Adolescent↗

PubMed2003

Hypertension care and control in underserved urban African American men: behavioral and physiologic outcomes at 36 months.

BACKGROUND: African American men with hypertension in low socioeconomic urban populations achieve poor rates of hypertension control and suffer early from its complications. METHODS: In a randomized clinical trial with 309 hypertensive urban African American men aged 21 to 54 years, we evaluated the effectiveness of a more intensive comprehensive educational-behavioral-pharmacologic intervention by a nurse practitioner-community health worker-physician (NP/CHW/MD) team and a less intensive education and referral intervention in controlling blood pressure (BP) and minimizing progression of left ventricular hypertrophy (LVH) and renal insufficiency. Changes in BP, left ventricular mass (LVM), and serum creatinine from baseline to 36 months were compared between groups. RESULTS: At 36 months, the mean systolic BP/diastolic BP change from baseline was -7.5/-10.1 mm Hg for the more intensive group and +3.4/-3.7 mm Hg for the less intensive group (P =.001 and.005 for between-group differences in systolic BP and diastolic BP, respectively). The proportion of men with controlled BP (<140/90 mm Hg) was 44% in the more intensive group and 31% in the less intensive group (P =.045). The LVM was significantly lower in the more intensive group than in the less intensive group (more intensive, 274 g; less intensive, 311 g; P =.004). There was a trend toward slowing of the progression of renal insufficiency (incidence of 50% increase in serum creatinine) in the more intensive group compared to the less intensive group (more intensive, 5.2%; less intensive, 8.0%; P =.08). CONCLUSIONS: During 36 months, the more intensive intervention led to a lower BP and decreased progression of LVH in a sample of hypertensive young African American men.

Adult↗

PubMed2003

Depression, substance use, adherence behaviors, and blood pressure in urban hypertensive black men.

Relationships between depression, alcohol and illicit drug use, adherence behaviors, and blood pressure (BP) were examined in 190 urban hypertensive Black men enrolled in an ongoing hypertension control clinical trial. More than one fourth (27.4%) of the sample scored greater than 16 on the Center for Epidemiological Studies-Depression Scale (CES-D), indicating a high risk of clinical depression. Depression was significantly associated with an increased likelihood of meeting Diagnostic and Statistical Manual of Mental Disorders (4th ed.) criteria for alcohol abuse or dependence (odds ratio = 5.2; 95% confidence interval = 1.897-14.214). The level of depression was significantly correlated with poor medication (r =.301) and poor dietary compliance (r =.164). Both alcohol intake and illicit drug use were significantly correlated with poor dietary compliance (r =.195 and.185, respectively) and smoking (r =.190 and.269, respectively). Although no direct relationship between depression and the level of BP was substantiated by multivariate analysis, findings of descriptive analyses revealed statistically significant associations among depression, substance use, poor adherence, and poor BP outcomes. Given the harsh environment in which a large number of young urban Black men live, the high prevalence of substance abuse might be an attempt to fight off depression. Further in-depth investigation is needed to identify the role of depression and BP control in urban young Blacks in order to construct effective interventions that address their unique needs.

Adult↗

PubMed2003

Predictors of older Korean Americans' participation in colorectal cancer screening.

BACKGROUND: Cancer is the second leading cause of death among Korean Americans aged 65 and older. Colorectal cancer is the second most commonly diagnosed cancer among Korean American women and the third among men. The purpose of this study was to examine the rates of colorectal cancer (CRC) screening and the correlates of screening tests. METHODS: The study employed cross-sectional face-to-face interviews with a sample of 205 Korean American elderly aged 60 and older. RESULTS: About 18% of respondents had ever had a fecal occult blood test (FOBT) and 11%, sigmoidoscopy. A history of bloody stool was related to having FOBT. In multiple logistic regression analyses, government assistance, routine checkups, having insurance, and speaking fluent English were associated with having FOBT. Marital status, proportion of time spent in the U.S., and general health status were related to having sigmoidoscopy. CONCLUSIONS: The findings suggest a need for further research addressing barriers to cancer screening in Korean Americans.

Age Factors↗

PubMed2002

Effect of smoking on the paradox of high waist-to-hip ratio and low body mass index.

OBJECTIVE: Research on diabetes mellitus (DM) indicates that people with a low body mass index (BMI) but a high waist-to-hip ratio (WHR) are in a particularly high-risk group. The purpose of this study was to investigate the prevalence of and the effect of smoking on this paradoxical relationship. RESEARCH METHODS AND PROCEDURES: Our study sample consisted of 3450 men and 4250 women who had participated in the Korean Nationwide Health Examination Survey. We divided the study sample into tertiles (low, medium, and high), according to the level of WHR and of BMI, which yielded nine different combinations. Individuals exhibiting so-called paradox A had the highest WHR and the lowest BMI. RESULTS: The prevalence of paradox A was 4.7% for men and 3.8% for women. The overall agreement of WHR and BMI groups was poor [for men: kappa = 0.31 and 95% confidence interval (CI) = 0.29 to 0.34; for women: kappa = 0.39 and 95% CI = 0.37 to 0.42 for women]. The odds ratios for subjects having paradox A were estimated using a logistic regression model after adjusting for age, age(2), height, education, smoking, use of alcohol, and exercise. The risk for paradox A among current smokers was 2.1-fold (95% CI, 1.5 to 3.0) higher for men and 2.5-fold (95% CI, 1.6 to 3.9) higher for women than for nonsmokers, after adjusting for age and covariates. DISCUSSION: Cigarette smoking may increase the risk of paradox A. The findings of this study should be crossvalidated to different populations.

Adult↗

PubMed2002

Breast and cervical cancer screening among Korean American elderly women.

The purpose of this study was to estimate the prevalence and correlates of breast and cervical cancer screening tests among Korean American elderly women. This study examined the effects of individual socio-demographic background, acculturation level (e.g., proportion of life spent in the US, spoken English proficiency), health status and access to health care on uptake of mammography and Pap smear tests in the past 2 years. Subjects were 130 Korean American women aged 60 and older living in the Greater Metropolitan Baltimore Area. A cross-sectional face-to-face interview was conducted. The 2-year prevalence was only 35% for mammography and 29% for Pap smear tests. In multiple logistic regression analysis, educational attainment, government support, multiple chronic conditions, and routine checkups were associated with having mammography. Age, acculturation and insurance were associated with having a Pap test. Taking advantage of the positive influence of identified covariates may increase the effectiveness of cancer control interventions among Korean American elderly women.

Journal Article↗

PubMed2002

Does hypertension increase mortality risk from lung cancer? A prospective cohort study on smoking, hypertension and lung cancer risk among Korean men.

OBJECTIVE: To examine the effects of hypertension on lung cancer prospectively and to determine the interactive effect of hypertension and smoking on lung cancer risk. DESIGN: A prospective cohort study. PARTICIPANTS: The cohort comprised 452,645 Korean men, aged 35-64 years, who received health insurance from the Korea Medical Insurance Corporation and who had biennial medical evaluations in 1992 and 1994. METHODS: Multivariate Cox proportional hazard models were tested, controlling for age, smoking status, exercise, body mass index, alcohol use, diabetes and serum cholesterol concentration. MAIN OUTCOME MEASURE: Deaths from lung cancer. RESULTS: At baseline, 261 080 persons (58.3%) were identified as current cigarette smokers. Between 1995 and 1999, 883 deaths from lung cancer (44.8/100,000 person-years) occurred. An initial finding indicated that hypertension increased the mortality risk of lung cancer [risk ratio (RR) 1.3, 95% confidence interval (CI) 1.1-1.5]. However, after stratification for smoking status, the risk ratio was increased only for current smokers (RR 1.4, 95% CI 1.2-1.6). When the interaction term was included in the multivariate model, there was a significant interactive effect of hypertension with current smoking (RR 1.8, 95% CI 1.0-3.1) on the risk of death from lung cancer, whereas the effect of hypertension itself did not attain significance. CONCLUSION: Hypertension was not an independent risk factor in lung cancer-related deaths, but it increased the modest risk of lung cancer death among current smokers.

Adult↗