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Biomedical subjects

Mohamed Halila

Publications and source records attributed to Mohamed Halila.

3 recordsLinked to original sources

[Solitary fibrous retroperitoneal tumour: report of two cases].

Solitary fibrous tumours are benign tumours, described for the first time by Klemperer and Rabin in 1931. They are mesenchymal tumours which usually arise in the pleura, while retroperitoneal sites have been rarely described. The authors report two cases of very large retroperitoneal tumours in two men aged 58 and 47 years, respectively, who consulted for abdominopelvic vaulting associated with gastrointestinal and urinary disorders. Ultrasound-guided biopsy suggested the diagnosis preoperatively in one case. In the light of these cases, the authors present a review of the main extrapleural sites described to date, as well as the most characteristic radiological, histological and immunohistochemical features in order to facilitate the diagnosis.

Adult↗

[Comparative analysis of conservative surgery versus radical nephrectomy for renal cancer].

OBJECTIVES: To compare the results of conservative surgery (CS) and radical nephrectomy (RN) for the treatment of renal cancer. MATERIAL AND METHOD: Between 1988 and 1999, more than 900 patients were operated for renal cancer in our department. We compared results of CS (partial nephrectomy and/or lumpectomy) to those of RN on 2 groups of matched patients with a similar sample size (n=62) in terms of morbidity, course of renal function, oncological efficacy and survival. RESULTS: The mean follow-up was more than 5 years for the two groups. This series comprised a predominance of localized (pT1 and pT2) low-grade (1 and 2) tumours: 80%. In our experience, CS was responsible for greater morbidity than RN, essentially because of indications of necessity compared to elective indications. Although the local recurrence rate was significantly higher after CS, analysis of overall and specific survival did not reveal any significant difference between the two groups. CONCLUSIONS: Conservative surgery appears to be a reasonable alternative to radical nephrectomy for the treatment of renal cancer in some indications and allows nephron sparing. This option appears to be all the more justified in view of the increasingly frequent discovery of small tumours in increasingly young patients. The development of minimally invasive techniques, particularly laparoscopy, is another aspect of this "minimal" trauma approach, but must be shown to ensure an equivalent oncological efficacy.

Adenocarcinoma↗

[Scrotal elephantiasis].

Scrotal elephantiasis (scrotal lymphoedema) is essentially observed in filaria endemic zones. It is very rare outside of these zones and is usually idiopathic, and rarely congenital or secondary. The authors report two cases of scrotal elephantiasis treated by wide resection of the pathological scrotal wall and penoscrotal repair with a good functional and cosmetic result.

Elephantiasis↗