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Mohammed El Hassouni

Publications and source records attributed to Mohammed El Hassouni.

2 recordsLinked to original sources

HOS-based image sequence noise removal.

In this paper, a new spatiotemporal filtering scheme is described for noise reduction in video sequences. For this purpose, the scheme processes each group of three consecutive sequence frames in two steps: 1) estimate motion between frames and 2) use motion vectors to get the final denoised current frame. A family of adaptive spatiotemporal L-filters is applied. A recursive implementation of these filters is used and compared with its nonrecursive counterpart. The motion trajectories are obtained recursively by a region-recursive estimation method. Both motion parameters and filter weights are computed by minimizing the kurtosis of error instead of mean squared error. Using the kurtosis in the algorithms adaptation is appropriate in the presence of mixed and impulsive noises. The filter performance is evaluated by considering different types of video sequences. Simulations show marked improvement in visual quality and SNRI measures cost as well as compared to those reported in literature.

Algorithms↗

Methionine sulfoxide reductases protect Ffh from oxidative damages in Escherichia coli.

In proteins, methionine residues are primary targets for oxidation. Methionine oxidation is reversed by methionine sulfoxide reductases A and B, a class of highly conserved enzymes. Ffh protein, a component of the ubiquitous signal recognition particle, contains a methionine-rich domain, interacting with a small 4.5S RNA. In vitro analyses reported here show that: (i) oxidized Ffh is unable to bind 4.5S RNA, (ii) oxidized Ffh contains methionine sulfoxide residues, (iii) oxidized Ffh is a substrate for MsrA and MsrB enzymes; and (iv) MsrA/B repairing activities allow oxidized Ffh to recover 4.5S RNA-binding abilities. In vivo analyses reveal that: (i) Ffh synthesized in the msrA msrB mutant contains methionine sulfoxide residues and is unstable, (ii) msrA msrB mutant requires high levels of Ffh synthesis for growth and (iii) msrA msrB mutation leads to defects in Ffh-dependent targeting of MalF. We conclude that MsrA and MsrB are required to repair Ffh oxidized by reactive oxygen species produced by aerobic metabolism, establishing an as-yet undescribed link between protein targeting and oxidation.

Amino Acid Sequence↗