Biomedical subjects

Monica Pop

Publications and source records attributed to Monica Pop.

11 recordsLinked to original sources

PubMed2006

[Ophthalmological involvement in rheumatic disease].

PURPOSE: The main objective of this study was to identify the prevalence of ocular manifestations in rheumatic patients admitted in a specialized clinic. METHODS: Information regarding rheumatic and ocular diseases was extracted from medical records system available in "Dr. I. Cantacuzino" Clinical Hospital from Bucharest. The prevalence of ocular involvement reported passively by rheumatologists (retrospective descriptive study of 375 different cases of rheumatic patients) was compared with the literature data. RESULTS: There were 45 cases of ocular manifestations. Keratoconjunctivitis sicca was noted in 16 patients with rheumatoid arthritis, two patients with systemic lupus erythematosus and one patient with scleroderma. Anterior uveitis was found in seven patients with ankylosing spondylitis, one patient with reactive arthritis, two patients with psoriatic arthritis and one patient with LES. Conjunctivitis was present in two patients with reactive arthritis. In LES ocular involvement also included four cases of retinal vasculitis. Complications clearly related to steroid therapy were nine cases of cataracts. One case with typical "bull's eye" maculopathy due to Hydroxychloroquine treatment was detected. CONCLUSIONS: The main conclusion of our study is that the rheumatic patients need to be referred to an ophthalmologist for the diagnosis and the optimal treatment of ocular involvement.

Aged↗

PubMed2004

[Paralytic lagophthalmos--treatment methods].

Paralytic lagophthalmos has a negative effect on patient. A patient's appearance is grossly distorted and many ocular problems due to exposure and dryness may interfere with the patient's ability to perform an occupation. This paper describes the management of the paralytic lagophthalmos. The medical treatment adds lubricants and the surgical treatment provides a better closure for the eye.

Blepharoptosis↗

PubMed2003

Abdominal miliary tuberculosis in a patient with AIDS: a case report.

We present a 34 year old patient, intravenous drug user, hospitalized with fever, distortion of general status, dry irritating cough, abdominal colicative pains, and we established the diagnosis of HIV infection advanced stage/AIDS; his antecedents revealed (August 2000) abdominal tuberculosis not treated during the last 3 months. He presented a pneumonia with Pneumocystis carinii during hospitalization. Death was due to a colon perforation with secundary peritonitis. Miliary tuberculous lesions in liver, spleen and colon were revealed at necropsy and cytomegalovirus was identified in necrotic samples also.

AIDS-Related Opportunistic Infections↗

PubMed2003

Multilocular colorectal tuberculosis and hypogammaglobulinemia.

We present the case of a young male patient admitted for weight loss, diarrhea and rectal bleeding. The patient belonged to a low social class and had associated hypogammaglobulinemia. The endoscopy revealed different localized ulcerations of he rectum and a stenosis. By barium enema and hydrosonography multiple stenotic lesions were observed. The pathological examinations detected lesions suggestive for intestinal tuberculosis. A specific therapy led to the improvement of his general state and to the disappearance of diarrhea and rectal bleeding.

Adult↗

PubMed2003

[Treatment of paralytic lagophthalmos].

Paralytic lagophthalmos has an negative effect on patient. A patient's appearance is grossly distorted and many ocular problems due to exposure and dryness may interfere with the patient's ability to perform an occupation. This paper describes the management of the paralytic lagophthalmos. The medical treatment adds lubricants and the surgical treatment provides a better closure for the eye.

Eyelid Diseases↗

PubMedDate not supplied

[Wegener granulomatosis--a case report].

The Wegener's granulomatosis is characterized by the involvement of the upper airways, the lower airways and the late involvement of the kidneys. The authors are presenting in this article, the case of a 44 years old man, which presented the three conditions mentioned above, with an early kidney involvement and who died due to a major complication of the disease: the intravascular disiminated coagulation and a multivisceral vascular involvement, despite the correct and early treatment.

Adult↗

PubMedDate not supplied

[Imaging in screening and diagnosis of lung cancer].

While the lung cancer is detected, the majority of the patients could not be surgical cured. Thus appears the great necessity of prevention, of a more efficient treatment and the developing of new methods for early detection. The first screening trials for lung cancer had negative results. None of the studies had no prove in decreasing of mortality by screening for lung cancer. The lack of sensitivity of thoracic radiographs and sputum cytology was leading the investigators to use the monoclonal antibodies in detecting the neoplastic changes in sputum, the spiral computerized tomography with low dose of radiations, the autofluorescence bronchoscopy and more recent the positron emission tomography, offering the possibility of reducing mortality by early detection in lung cancer.

Antibodies, Monoclonal↗

PubMedDate not supplied

[Rare histological type of pulmonary adenocarcinoma--two clinical cases].

Two cases of primary signet-ring cell adenocarcinoma of the lung are presented. The patients were: a 53-year-old man with a left lung mass and a 40-year-old woman with a right lung mass. Endobronchial biopsy performed after fiber-bronchoscopy reveal this rare histological type for pulmonary localizations of neoplasms. It is well known that this histological type is found in digestive localizations of neoplasms, especially gastric, but in these two cases we excluded such a neoplasm. The tumor we found in these two cases is a very rare intrapulmonary neoplasm with a poor clinical course and prognosis. Signet-ring cell adenocarcinoma is a recently described neoplasm whose histology is different from most lung adenocarcinomas and represented a spectrum of malignant potential. Little is known of the behaviour of more malignant subtype.

Adult↗

PubMedDate not supplied

[Evolution of pulmonary metastasis in osteosarcoma].

Osteosarcomas are tumors with a high aggressivity which gives early and frequent pulmonary metastasis. These patients have a poor prognosis. The reveal of prognosis factors and early detection of pulmonary relapse would influence the outcome of these patients. We performed a retrospective study at Oncology Institute from Cluj, observing 35 patients with osteosarcomas and pulmonary metastasis at the onset or in evolution. We tried to quantify some prognosis factors. We observed the predominance of male sex (20), from urban area (25), with age between 11-20 years (16 cases), with primary tumors localized more frequently at the limbs. Pulmonary metastasis were shown without free interval from the onset (12 patients), or in the first years (17 cases), more frequently with multiples locations (26 cases). 28 patients were submitted to surgical treatment for cure of primary tumor, 18 chemotherapy, and pulmonary metastasis resection in 5 cases only. The outcome under treatment was favorable in 4 cases only, compared with other studies. Early detection of pulmonary metastasis and aggressive therapy with augmentation of resection criteria for pulmonary metastasis would improve the prognosis of this patients.

Adolescent↗

PubMedDate not supplied

[Diagnostic difficulties in generalized tuberculosis--a case report].

Generalized tuberculosis (characterized by the presence in several organs of small tuberculous granulations surrounded by normal tissue) is becoming a more and more seldom disease, having an unpredictable evolution and prognosis. The diagnosis is often difficult. We present the case of a young woman, 29 years old, in which the diagnosis established in a late stage could have been fatal.

Adult↗

PubMedDate not supplied

[Difficult diagnosis in a case of pulmonary epidermoid carcinoma].

We present a case of a 66 years old male patient, from urban area, smoker for 54 years, without special antecedents, hospitalized in our service with a pulmonary right lower lobe abscess, whose onset was 4 months ago, persistent under treatment in another pneumology service. Clinically and radiologically we suspected a pulmonary excavated right lower lobe neoplasia, but unsustained by fiber-bronchoscopy and thoracic computer tomography. By this reason the patient underwent exploratory thoracotomy and the diagnosis was confirmed by the biopsy of the resected specimen: pulmonary epidermoid carcinoma. The short term outcome was favourable.

Aged↗