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Biomedical subjects

Mustafa Güler

Publications and source records attributed to Mustafa Güler.

9 recordsLinked to original sources
PubMed2006

Assessment of spatial variability in some soil properties as related to soil salinity and alkalinity in Bafra plain in northern Turkey.

The objectives of this study were to assess the variability in soil properties affecting salinity and alkalinity, and to analyze spatial distribution patterns of salinity (EC) and alkalinity (ESP) in the plain, which was used irrigation agriculture with low quality waters. Soil samples were collected from 0-30 cm, 30-60 cm, 60-90 cm and 90-120 cm soil depths at 60 sampling sites. Soil pH had the minimum variability, and hydraulic conductivity (Ks) had the maximum variability at all depths. The mean values of pH, EC, ESP and Ks increased while the mean values of CEC decreased with soil depth. Values pH, EC and ESP were generally high in the east and northeastern sides. Soil properties indicated moderate to strong spatial dependence. ESP and pH were moderately spatially dependent for three of the four depths, EC exhibited moderate spatial dependence for one of the four depths, CEC had a moderate spatial dependence at all depths, and Ks exhibited a strong spatial dependence. EC, CEC, and ESP were considerably variable in small distances. The spatial variability in small distances of EC, CEC, pH and ESP generally increased with depth. All geostatistical range values were greater than 1230 m. It was inferred that the strong spatial dependency of soil properties would be resulted in extrinsic factors such as ground water level, drainage, irrigation systems and microtopography.

Agriculture↗
PubMed2006

Using landsat data to determine land use/land cover changes in Samsun, Turkey.

The rapid industrialization and urbanization of an area require quick preparation of actual land use/land cover (LU/LC) maps in order to detect and avoid overuse and damage of the landscape beyond sustainable development limits. Remote sensing technology fits well for long-term monitoring and assessment of such effects. The aim of this study was to analyze LU/LC changes between 1980 and 1999 in Samsun, Turkey, using satellite images. Three Landsat images from 1980, 1987 and 1999 were used to determine changes. A post classification technique was used based on a hybrid classification approach (unsupervised and supervised). Images were classified into six LU/LC types; urban, agriculture, dense forest, open forest-hazelnut, barren land and water area. It is found that significant changes in land cover occurred over the study period. The results showed an increase in urban, open forest/hazelnut, barren land and water area and a decrease in agriculture and dense forest in between 1980 and 1999. In this period, urban land increased from 0.77% to 2.47% of the total area, primarily due to conversions from agricultural land and forest to a lesser degree. While the area of dense forest decreased from 41.09% to 29.64% of the total area, the area of open forest and hazelnut increased from 6.73% to 11.88%.

Conservation of Natural Resources↗
PubMed2006

Combined approach to a peripheral congenital arteriovenous malformation: surgery and embolization.

A 28-year-old woman with a complex peripheral congenital arteriovenous malformation in the left shoulder and left upper arm was treated by a combination of surgery and embolization. In the consecutive four operations, the major feeding arteries of the arteriovenous malformation were ligated, but as her complaints increased, transcatheter embolization was planned for releaving the symptoms in the first aspect. A total of eight embolization sessions were performed with Onyx during the 3-year period. The arteriovenous communications were occluded by embolization, with approximately more than an 80% decrease in the lesion size angiographically. After these interventions, the patient's symptoms improved clinically and dyspnea was lessened. Peripheral congenital arteriovenous malformation is a rare and therapeutically challenging condition in which a combination of surgery and embolization would be necessary to obtain a good result.

Adult↗
PubMed2006

Multivariate analysis for operative mortality in obstructive prosthetic valve dysfunction due to pannus and thrombus formation.

The objective of the present study was to investigate the risk factors for early hospital mortality in reoperations performed for obstructive prosthetic valve dysfunction. Between January 1994 and April 2005, 63 patients underwent reoperation for obstructive prosthetic valve dysfunction. The mean age of the patients was 40.3 +/- 12.8 years. The mitral valve was replaced in 47 (74.6%) patients, the aortic valve in 6 (9.5%) patients, and both valves in 10 (15.9%) patients. Forty-three (68.2%) patients underwent emergency reoperations. Early hospital mortality occurred in 13 (20.6%) patients. The ethiology of the valve dysfunction was pannus formation in 45 (71.4%) patients and thrombus formation in 18 (28.6%). Pannus and thrombus were localized at the atrial side of the prosthetic valve in 15 (23.9%) patients, at the ventricular side in 13 (20.6%), and at both sides in 35 (55.5%). Inadequate anticoagulation was diagnosed in 28 of 63 (44.4%) patients. The mean INR level in these 28 patients was 1.43 +/- 0.24. In multivariate analysis, the only risk factor for early hospital mortality was left ventricular ejection fraction (P = 0.015; Odds: 0.000, 95% CI: 0.000-0.043). It is concluded reoperations for prosthetic valve dysfunction have a high mortality rate. This study revealed that left ventricular dysfunction is the major determinant of surgical mortality in patients requiring reoperation for valve dysfunction due to pannus or thrombus.

Adolescent↗
PubMed2005

Operative mortality after valvular reoperations.

BACKGROUND: To determine the incidence and risk factors of mortality and morbidity in valvular reoperations. METHODS: Between January 1993 and December 2003, 309 valvular reoperations were performed. The reasons for reoperations were reconstructive surgery in first operation (110 patients, 35.5%), prosthetic valve endocarditis (12 patients, 3.8%), periprosthetic leakage (32 patients, 10.3%), new valve degenerations (12 patients, 3.8%), bioprosthetic dysfunction (92 patients, 29.7%), acute thrombotic stuck valve (30 patients, 9.7%), and pannus formation (21 patients, 6.7%). Mitral valves were replaced in 235 patients, aortic valves were replaced in 32 patients, 24 patients had aortic and mitral valve replacements, 2 patients had mitral and tricuspid valve replacements, and reconstruction of periprosthetic leakage was held in 16 patients. 264 patients had elective surgery, whereas 45 were operated on emergency basis. RESULTS: Hospital mortality was 14.23%. Mortality rate was found to be 10.6% for elective cases and 35.5% for emergency cases. Permanent pacemaker was required in 12 patients, 3 patients had cerebrovascular events, and mediastinitis was observed in 1 patient. Multivariate analysis demonstrated that age > 60 (P = .006; OR 7.3, 95% CI 1.7-30.1), emergency surgery (P = .001; OR 8.1, 95% CI 2.4-27.7), preoperative cerebrovascular accident (P = .003; OR 11.8, 95% CI 2.458.7), and concomitant ascending aorta replacement (P < .001; OR 27.4, 95% CI 6-127) were independent risk factors. CONCLUSION: Valvular reoperations can be carried out with acceptable morbidity and mortality in elective operations but mortality rates are still very high in emergent cases.

Adult↗
PubMed2005

Simultaneous Carotid Endarterectomy and Coronary Revascularization is Safe Using Either On-Pump or Off-Pump Technique.

The appropriate surgical strategy for patients with combined carotid and coronary artery disease remains controversial. We retrospectively compared our surgical results for 2 types of approaches in this disorder. The records of 76 patients consecutively operated on for carotid and coronary artery disease between August 1993 and October 2004 were reviewed. There were 18 males (66.6%) and 9 females (33.3%) in group I. Group II consisted of 35 males (71.4%) and 14 females (28.5%). The patients were divided into two groups: patients with combined off-pump coronary artery bypass and carotid endarterectomy (group I, n = 27), and those with one-stage on-pump coronary artery bypass and carotid endarterectomy (group II, n = 49). Surgical mortality and morbidity and late outcome were compared among the two groups. The average number of grafts was 1.2 +/- 0.4, with the average operative time of 3.3 +/- 0.3 hours in group I, and 2.3 +/- 0.5 grafts with operative time of 4.6 +/- 0.4 hours in group II (P < 0.001 and P < 0.001, respectively). There was 1 death (3.7%) in group I and 2 deaths (4.8%) in group II (P = 0.937). No patient from either group I or group II had postoperative stroke. Mean hospital stay was 7.4 +/- 1.9 days in group I and 11.3 +/- 1.7 days in group II (P < 0.001). At a mean follow-up of 5.5 +/- 3.3 years in group I, 1 patient had contralateral carotid endarterectomy (3.7%). Group II had a mean follow-up of 5.2 +/- 3.0 years and contralateral carotid endarterectomy was performed in 1 patient (2.0%). There were no late strokes or deaths in either group. Combined coronary artery bypass grafting and carotid endarterectomy using 2 different types of technique is a safe and effective procedure in patients with significant concomitant monolateral carotid and coronary artery disease.

Cardiac Surgical Procedures↗
PubMed2004

Sleep quality and immune functions in rheumatoid arthritis patients with and without major depression.

The purpose of this study was to determine the discriminative factors between rheumatoid arthritis (RA) patients with and without major depression (MD). We assessed subjective sleep quality, pain, and cell-mediated immune functions in RA patients with (n = 20) and without (n = 20) MD by using Pittsburgh Sleep Quality Index (PSQI), visual analogue scale (VAS), and fluorescein isothiocyanat (FITC) labeled CD3, CD4, CD8, CDI9, CD45, CD56, and HLADR T monoclonal antibodies by flow cytometry. We found that the RA patients with MD had significantly higher pain level, poorer sleep equality, higher HDRS points, and higher HLADR T cell level than those without MD; and that these variables are discriminant factors between patient groups. These findings suggest that the RA patients with MD may be differentiated from those without MD by using VAS, PSQI, and HLADR levels; that these variables correctly classify the depressed and non depressed groups up to an accuracy level of 96.8%.

Adolescent↗
PubMedDate not supplied

Does mediastinitis affect the graft patency?

As inflammation began to be recognized as a major contributor to the pathogenesis of atherosclerosis, we evaluated the patients that developed mediastinitis, a long-standing inflammatory process, after coronary artery bypass grafting. There are many studies that have focused on the graft patency. But, till now, no study has been done to detect the effects of mediastinitis to graft patency. So, we aimed to detect the effect of mediastinitis on the graft patency in patients who have undergone coronary artery bypass surgery. Sixteen of 45 patients who have been operated upon for coronary artery bypass surgery and developed mediastinitis, which was treated with open drainage and mediastinal irrigation with late wound closure, were included in the study. The mean age of the patients was 55 +/- 11 (range 35-69) and nine of the patients were male. The graft patency was evaluated with control coronary angiographies after a mean period of 30.42 +/- 43.17 months (range 1-132). The left internal thoracic artery was patent in all patients (100%). Right internal thoracic artery patency rate was 50% (1/2). One individual bypassed radial artery was patent, whereas the sequential bypassed graft was occluded. The patency ratio of radial artery anastomosis was 33% (1/3). Twelve of the 17 saphenous vein grafts were patent (70.58%). The total number of patent distal anastomosis was 30/38 (78.94%). When compared with the graft patency of patients without infection, it was found that mediastinitis does not affect the graft patency rates adversely.

Adult↗