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Biomedical subjects

Mutaz B Habal

Publications and source records attributed to Mutaz B Habal.

At least 37 records · Page 2Linked to original sources
PubMed2004

In search of causative factors of deformational plagiocephaly.

This is a preliminary study of 37 infants with deformational plagiocephaly. In this first effort to create a profile of factors that may contribute to the onset and progress of developmental plagiocephaly, parents were interviewed concerning selected practices before and immediately after the birth of their infants. Results of the study do not reveal a clear or concise pattern of factors that may contribute to this condition. There needs to be additional research on the benefits and potential hazards of sleep position to infants as one of the factors that may contribute to deformational plagiocephaly.

Birth Order↗
PubMed2003

Avoiding the sequela associated with deformational plagiocephaly.

Over the last decade, infants with deformities in the craniofacial skeleton have been seen at our craniofacial center, and similar observations have been noted in infants seen for evaluation and management after birth, where there are not any evident pathological findings such as craniosynostosis or another known genetic disorder. The known condition of deformational plagiocephaly has been related to a sequela of the infants being placed on their back for sleep. The change in the position of the infants to sleep on their back was altered from the traditional position, where infants were placed in the prone position for many decades in the past in the Western world. A special study was initiated to compile meaningful data to help those in the field pursue their treatment of affected children in a systematic and comprehensive manner. Avoidance of unnecessary surgery was essential in those children unless the deformational condition persisted and was not resolvable by nonsurgical means and change in the cultural habitat.

Adolescent↗
PubMed2002

Controlled bone regeneration: the ultimate process in bone repair.

The main goal of bone healing, besides the healing of the bone, is ensuring that the dynamic system of repair is under biologic control. To do so, the soft tissue has to be kept isolated to avoid any herniation into the bony defect, that would produce and interfere with the bone interface or collapse the original defect resulting in a relapse.

Adolescent↗
PubMed2002

Silicone gel breast implant failure: evaluation of properties of shells and gels for explanted prostheses and meta-analysis of literature rupture data.

After 30 years of clinical use, the 1992 Food and Drug Administration moratorium on silicone gel breast implants (SGBIs) resulted from a paucity of scientific data concerning their safety. The frequency of rupture and reoperative procedures was not known, nor were reliable data available for changes in the physical properties of shells and the composition of gels that might lead to SGBI failure. For this reason the authors conducted large-cohort meta-analyses of failure data for SGBIs based on numerous literature reports and also investigated systematically shell and gel properties from explanted SGBIs. They report their failure analysis data for more than 9,770 SGBIs (an update of an earlier study of more than 8,000 implants) as well an examination of the properties of shells and gels for 74 explanted SGBIs that ranged in age from 2 to 19 years (mean implanted age, 9.9 years). The explants tested were from several different manufacturers. For the modest-size explant cohort that was tested, 31 of 74 implants (42%) were found to be ruptured (some extensively). Even many intact shells were so weakened that only 51 shells had sufficient strength to enable preparation of samples for testing of mechanical properties and for analysis of composition by solvent extraction. Shells were found to contain 15 to 25% of extractable silicone. Exhaustive extraction of gels showed that they actually contained very little crosslinked silicone--85 to 95% being extractable soluble silicone fluid. Tensile and tear strengths of explanted silicone elastomer shells were lower than unimplanted prostheses and were generally well below reported manufacturers' values. This updated large-cohort failure analysis continues to show that shell rupture is related directly to implant duration (e.g., from analysis of variance statistics, 26% failure at 3.9 years, 47% at 10.3 years, 69% at 17.8 years; < or = 0.001). However, for the relatively small series of explants for which physical property data are reported, no significant correlation was observed between implant duration and the degradation of implant strength. It therefore appears most reasonable to conclude that after early weakening of shells as a result of swelling of the shell elastomer by diffusion of silicone oil from the gel, SGBI failure can occur in a time-dependent manner as a result of continuing implant motion and cyclic stresses that are exacerbated by stress concentration at thin areas, defects, and folds in the shells.

Breast Implants↗