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Biomedical subjects

N A Agadzhanian

Publications and source records attributed to N A Agadzhanian.

At least 19 recordsLinked to original sources
PubMed2006

[Hypoxic training -- effective method of raising skin vitality in cases of local plastic operations].

In spite of the complications after expander use the advantages of local plastics predetermine constant return to the method. Systemic use of hypoxic training produces stimulating effect on the skin microcirculation and can be used widely in clinical surgical practice in cases of local plastic operations to prevent possible complications reducing consequences of blood supply disturbance and tissue oxygen provision. The method of hypoxic adaptation let us receive as non-medicamentous mean to prepare for shorter period of time more vital flap.

Adaptation, Physiological↗
PubMed2005

[The effect of phonational load on parameters of cardiorespiratory system in hypotonic dysphonia].

Cardiointervalometry was used to investigate functional parameters of the cardiorespiratory system during text reading. A total of healthy women aged from 17 to 28 years and 11 women with hypotonic dysphonia 17 to 31 years of age entered the study. Both groups exhibited a low index of parasympathetic component of cardiorhythm regulation in shortening of the RR-interval. Correlation inhalation/expiration has changed with prolongation of inhalation and shortening of expiration in reading in women suffering from hypotonic dysphonia. Parameters of the respiratory cycle at rest did not correlate with relevant parameters in reading text in both groups.

Adolescent↗
PubMed2003

[Classification of hypoxia, hypo-, and hypercapnia].

The new classifications of hypoxical, hypo- and hypercapnical conditions are elaborated. They take into account the ecological factors in the development of various kinds of exogenic hypoxia, hypercapnia. For the first time the positive sides of physiological hypoxia and hypercapnia are brought in. In all classification til the last days hypoxia was considered as pathological process only. However hypoxia can be met in different physiologic conditions of organism: internal period of fetus development, hard physical work, increased sportsmen activity, hypoxia after hearty meal, hypoxia of aged organism. The same it is possible to say about the hypo- and hypercapnical conditions.

Adaptation, Physiological↗
PubMed2003

[Role of carotid chemoreceptors in formation of adaptive reactions in animals].

After surgical denervation of sinocarotid reflexogenic zones and bilateral glomectomy in white laboratory rats oxygen consumption, rectal temperature, rate of cardial contractions and thermoregulatory activity of skeletal muscles display authentic increase. Glomectomy results in decreasing calorigecic effect of noradrenaline. Compensatory increase of thermoregulatory activity of sceletal muscles in response to beta-adrenogenic blocade with inderal in post-glomectomic animals is authentically less, than before inactivation of carotid receptors. In animals after carotid glomectomy resistance to acute hypoxia is clearly reduced. True reduction of number of erythrocytes, of hemoglobin concentration, of hematocrite parameter in post glomectic animals was found, which indicates anemisation phenomena. It was found that glomectomy after adaptation of animals in the mountains of Tien Shan at the height of 3200 m during 30 days didn't substantively change resistance to acute hypoxia. Resistance to acute hypoxia of animals living on mountains (susliks, marmots) is higher than of animals living on plains. Glomectomy performed on animals living on mountain resulted in an insignificant decrease in resistance to acute hypoxia. Resistance to acute hypoxia in postglomectic animals was found to be directly linked with absolute amount of hemoglobin concentration and erythrocyte number. In that way denervation of sinocarotid reflexogenic zones and bilateral glomectomy is an adequate method of comparative research of functions regulation mechanism during formation of adaptive responses in animals in dependence of various factors of external environment in norm, as well, as in pathology.

Adaptation, Physiological↗
PubMed2002

[Electrophysiological and neurochemical analysis of the biological effects of disturbances of Earth's magnetic field].

Geomagnetic effects on quantitative characteristics of alpha-rhythm were assessed by shifts in electroencephalograms recorded in 126 essentially healthy human subjects and changes in lipid metabolism in the cortex and white matter in 140 white rats. Indices of the geomagnetic activity were D, H and Z-components. The method of "epoch superposition" revealed an inconsistent alpha-rhythm depression and flattening out of the interhemispheric functional asymmetry against persistently high electrical activity in the right hemisphere, and biochemical asymmetry in consequence of different lipid transformation processes. Spotlighted were some nonspecific adaptive reactions to changes in the environment and stressful agents.

Adaptation, Physiological↗
PubMed2001

[Specific aspects of hemostasis and lipid peroxidation in thrombocyte membranes during expedition and shift organization of labor].

The aim of the present study is to investigate dynamics of the hemostasis system and structural and functional state of thrombocyte membranes by the LPO and AOD parameters under the conditions of expedition and shift organization of labour of worker tripping from the West Siberia middle latitudes to the Far North. A trend to hypocoagulemia and increases in LPO and AOD reactions were characteristic of the type-1 (adaptive) reaction. The type-2 (hypotensive) reaction included a trend to hypercoagulemia, an increase in LPO and a decrease in AOD reactions in thrombocyte membranes as well as a hypertensive reaction during the whole shift period. The type-3 (asthenic) reaction was described by hypocoagulemia, an increase in the amount of LPO products with a simultaneous decrease in the AOD activity and asthenic sleep disturbance.

Adult↗
PubMed2001

[Influence of geomagnetic activity on the cardiorespiratory system in healthy humans].

Changes in a number of respiration and circulation parameters during magnetic storms of varying intensity were analyzed in 126 normal humans belonging to two age groups: 19-21 yr. old young men and women (29 of each) and 51-53 yr. old men (n = 36) and women (n = 32). Geomagnetic components D, H and Z were used. Systolic pressure, respiration volume, minute respiration volume and peak expiration rate were shown to be the most labile characteristics of the cardiorespiratory system responding by increases on magnetodisturbed days. The parameters under study exhibited sexual and age differences equally on quiescent and magnetodisturbed days. Adaptation to growing tension of the magnetic field of Earth involves the neuroendocrine system and manifests itself by activation of the sympathetic nervous system entailing relative shifts in the cardiorespiratory parameters under study.

Adult↗
PubMed1999

[Public and occupational health and industrial ecology].

The authors present results of theoretic and experimental analysis of ecologic safety in Russia. New composite discipline--"human ecology"--takes an important place in solution of medical and ecologic problems associated with correlation between natural and occupational factors influencing humans. Present medical, social and ecologic circumstances define the most vital scientific and applied directions covering medical and ecologic humanization of occupational and natural environment for humanity nowadays. Those directions are prophylaxis of ecologic stress, specification of informational technology for medical and occupational monitoring, creation of data bank on human ecology.

Ecology↗
PubMed1999

[Functional homology in response of human cardiorespiratory system to effects of hypoxia and hypercapnia under different environmental conditions].

The authors studied physiologic peculiarities associated with cardiorespiratory response to hypoxia and hypercapnia in various climate and geographic conditions, to combined effects of hypoxia, hypercapnia and physical burden, in artificial atmosphere with various velocity of hypoxia and hypercapnia increase. The studies were based on a hypothesis of universal mechanism that describes regulation of gas-transporting system and is aimed to supply oxygen to the body under ecologic hazards. The authors revealed similarity of circulatory and respiratory responses to hypoxia and hypercapnia in various ecologic circumstances.

Cardiovascular Physiological Phenomena↗
PubMed1997

[Nikolaĭ Nikalaevich Sirotinin and his school].

In a brief review of 50-year scientific activity of professor N. N. Sirotinin and his students the authors emphasize that this broad-minded scientist contributed to development of such disciplines as microbiology, pathophysiology, high-altitude, aerospace medicine. However, his main goal was evolution of reactivity and resistance, approaches to perfection of human health and performance. Much attention was paid to effects of low partial oxygen pressure on human and animal body, to hypoxic states of different origin. Methods of hypoxytherapy and hypoxic training are widely used in Russia and abroad. The contribution of academician N. N. Sirotinin to modern pathophysiology, high-altitude and aerospace physiology, internal and sport medicine is highly appreciated in Russia.

Aerospace Medicine↗
PubMed1996

[V. V. Strel'tsov: founder of the Institute and father of our country's aerospace medicine].

The paper gives an account of the scientific-and-practical activity of the prominent Soviet physiologist V. V. Streltsov, Head of the Fourth Sector, Research Sanitary Institute, and the initiator of the Aviation Medicine Institute. He was a brilliant experimenter, innovator, organizer of unique researches who developed the physiological aspects of high altitude, speedy, night and instrumental blind flights, the problems of stratospheric aviation. He made the first experimental ascent in the altitude chamber. He was one of the first aviation physicians who made a parachute jump. He was the first inflight medical investigator who tested the on-board oxygen equipment in group cross-country flight on the closed route Moscow-Kharkov-Moscow.

Academies and Institutes↗