[A latent course of chronic tonsillitis with rheumatoid syndrome].
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Biomedical subjects
Publications and source records attributed to N A Antonova.
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The paper presents a comparative analysis of surgical outcomes in chronic maxillary ethmoiditis for radical and endonasal endoscopic operations in 85 patients. Objective control was performed with morphological, endoscopic and functional methods.
Parameters of cardioelectric field on body surface and propagation of excitation in ventricular myocardium during initial activation were studied using multichannel synchronous electrocardiotopography. It was shown that inversion of areas of negative and positive potentials of cardioelectric field on body surface at the moment of excitation propagation to the epicardium reflected changes in the main direction of excitation wavefront in ventricles.
The paper outlines the authors' clinical and morphological experience in clinically rehabilitating children with adenoid vegetations and sinusitis. Retrospective morphological and immunohistological studies have revealed that the structure of adenoids corresponds to the morphology of humoral and cellular immune responses. This enables adenoid vegetations to be regarded as an actively functioning secondary immunity organ that requires maximum sparing in young children.
The structure of the nasal septum was studied on 34 samples obtained from dead bodies of children aged 3 to 14. The septums were removed from the skull cavity. The morphometric studies consisted of measurements of the anteroposerior, superior-inferior, septum and its area, as well as composite anatomical structures. It is shown that the size and area of the septum and its anatomical structures undergo age-specific changes which are not regular. The data should be accounted for in correction of nasal septum structural defects in children of different age.
The data accumulated within the last years required revision of the indications to the use of antibiotics in treatment of pertussis. One of the aims of antibiotic therapy in pertussis was to prevent colonization of B. pertussis in the respiratory tracts. With that end in view the choice of antibiotics should be limited by those, to which the pathogen is the most sensitive i.e. erythromycin, ampicillin and augmentin. Comparative efficacy of erythromycin and ampicillin during the first 2 weeks of the disease was studied in 79 infants at the age not older than 1 year with pertussis and it was shown that erythromycin was advantageous by its therapeutic activity and less side effects. Expedience of the antibiotic therapy during the spastic period for providing a preventive effect on development of bronchopulmonary complications was studied in 201 patients with pertussis. No preventive effect of the antibiotics on development of the bronchopulmonary complications defined by the secondary bacterial flora was recorded. In the group of the patients treated with the antibiotics prophylactically (group 1) the complications were 2.6 times more frequent than in the patients treated with pathogenetic agents alone (group 2). Intrahospital pneumonia developed in 8.9 per cent of the patients in group 1 and in 1.5 per cent of the patients in group 2. Therefore, antibiotics should not be used at the late periods of pertussis for prophylaxis of secondary bacterial complications.
A 47-year-old man had ulcero-necrotic pharyngitis examined and treated without effect in various Moscow hospitals for 3 months. The diagnosis was established after histologic and bacteriologic examination of the biopsy.
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In 160 patients, postoperative healing of stenoses of hollow neck organs of various etiology was examined clinically and morphologically. All the patients were divided into 4 groups in terms of the etiological factor as follows: Group 1 (60 patients)--patients with post-traumatic stenoses of the larynx and trachea; Group 2 (34 patients)--patients with post-resuscitation stenoses of the larynx and trachea; Group 3 (38 patients)--patients with bilateral laryngoparalysis that developed after strumectomy; Group 4 (28 patients)--patients with postburn deformation of the pharyngolarynx and esophagus. Pathomorphological changes typical of a chronic inflammatory process were detected in the frontal neck tissues (skin, muscles, cartilages, mucous membrane) of all the patients. Morphologically, the frontal neck tissues were similar in all the patients. In view of this, a large number of suppurative-necrotic complications seen after surgery of stenoses of hollow neck organs (up to 45%) can be attributed to pathological lesions in the frontal neck tissues.
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