PubMed Health⌕ Search

Biomedical subjects

N A Baranets

Publications and source records attributed to N A Baranets.

4 recordsLinked to original sources
PubMed1985

[Prognostic value of determining the succinate dehydrogenase activity of lymphocytes and the therapeutic effectiveness of sodium succinate in resuscitation of rats].

In the experiments on male rats recovered after clinical death caused by acute hemorrhage and mechanical asphyxia undulatory changes of lymphocyte succinate dehydrogenase activity were revealed: enzyme inhibition during clinical death, activation in the first minutes of resuscitation with subsequent moderate reduction in activity. Lymphocyte succinate dehydrogenase activity was shown to be a reliable prognostic criterion. Pre-injection of sodium succinate at a dose of 20 mg/kg improved considerably the resuscitation results especially during the first two days of rehabilitation period.

Animals↗
PubMedDate not supplied

[Disordered cardiac contractility after clinical death caused by acute blood loss].

The regularities of development of postresuscitation cardiodepression were studied in experiments on outbred male rats resuscitated after 4-min clinical death from acute blood loss. The studies were carried out for the whole organism, isolated isovolumetrically contracting heart, and for the isolated papillary muscle. As a result of acute critical blood loss, the functional reserve of the myocardium dropped and fatigue rapidly developed, progressing to asystole and fibrillation during the maximal exercise. Cardiodepression was expressed most of all during the first day, particularly during the first hours after resuscitation. Later the contractility gradually normalized, and 3 months after resuscitation it did not reliably differ from the control. The disorders involved the relaxation processes most of all.

Acute Disease↗