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Biomedical subjects

N A Chigogidze

Publications and source records attributed to N A Chigogidze.

At least 19 recordsLinked to original sources
PubMed2003

Results of hospital bypass angiography in patients with coronary artery disease undergoing arterial and vein myocardial revascularization.

This paper analyzes the results of 94 coronary artery bypass grafts accomplished at the Department of Surgical Treatment of Concomitant Lesions of Coronary and Peripheral Arteries, A.N. Bakulev SCCVS, RAMS, in patients with coronary artery disease (CAD) provided control hospital bypass angiography over the period 1998 to 2002. Control bypass angiography revealed thrombosis of 11.7% of vein and of 1.5% of arterial grafts. The main causes of vein graft thromboses were: bypass grafting of small coronary arteries, that of the coronary arteries with so-called 'immature' stenoses, and mediastinitis. The data presented herein evidence that hospital arterial bypass graft provides for a considerably higher percentage of competence versus vein bypass graft. Hospital bypass angiography is essentially safe while its findings allow to make a detailed analysis of complications whereby upgrading the efficacy of operations.

Arteries↗
PubMed2003

[Endovascular embolization of arteriosinusoidal fistula with new coil type].

A case report for endovascular embolization of cerebral arteriosinusoidal fistula with new coil type is presented. Endovascular procedure enabled to avoid extensive surgical intervention and provided the evidence of its effectiveness for management of patients with cerebral arteriovenous malformations.

Adult↗
PubMed1991

Surgical treatment of the Wolff-Parkinson-White syndrome by epicardial electrical ablation.

A new operation to eliminate accessory pathways--epicardial electrical ablation--is described. In a group of 201 patients without concomitant disease, the mortality rate was 0.5% and the overall efficacy of the operation for free wall accessory pathways, 98%. A retrospective clinical study of 44 unselected patients was performed to examine how safe epicardial electrical ablation is. The criteria for intraoperative effectiveness were disappearance of both the delta wave and retrograde conduction and inability to induce tachycardia. In the postoperative and follow-up periods, the following were reviewed: electrocardiograms; Holter monitor recordings (24 to 26 hours); release of the myocardial-specific isoenzyme of creatine kinase; intracardiac hemodynamics and myocardial contractility (radionuclide methods); selective coronary arteriograms and ventriculograms; mean work capacity (bicycle ergometer); diagnostic transesophageal electrical stimulation; and histology of the area of ablation. The main conclusion of this study is that epicardial electrical ablation is a highly efficient and safe operation for surgical elimination of parietal accessory pathways in patients with Wolff-Parkinson-White syndrome. Its advantages are its technical simplicity and the opportunity to review results immediately during the operation.

Adolescent↗
PubMed1991

Diagnosis and surgical treatment of tachycardias in patients with nodoventricular fibers.

From May, 1982 to April, 1991 25 patients were examined and 23 had open heart surgery for tachycardia with nodoventricular fibers (NVF) participation. All patients suffered tachycardia for more than 5 years. Most patients had syncope. The patients had: true NVF tachycardia (11), atrioventricular node reentry tachycardia (5), orthodromic atrioventricular tachycardia (AVT) (5), and atrial flutter (1) all with passive propagation through NVF, pseudonodoventricular tachycardia (AVT with slow accessory pathways) two patients. In 18 out of the 23 who had surgery there were no signs of preexcitation or tachycardia events in the follow-up period.

Adolescent↗
PubMed1990

[Surgical treatment of ventricular allorhythmia and non-ischemic tachycardia].

The paper deals with the problems in the diagnosis and treatment of patients with the most malignant rhythm disturbances, i. e. ventricular arrhythmias. A great emphasis is laid on the so-called "primary" arrhythmias appearing without a manifest cardiac abnormality. The arrhythmias proceed unfavorably and are followed by profound morphofunctional myocardial changes occurring chiefly in the upper portions of the ventricular septum, more frequently on the right. Cryodestruction of arrhythmogenic areas is an effective method for surgical correction of arrhythmias having an unfavorable course.

Adolescent↗
PubMed1990

[Percutaneous transcatheter assisted circulation].

A new system of percutaneous transcatheter auxiliary circulation of blood was developed and approved in the period between 1988 and 1989. The system includes a portable centrifugal pump and special catheters with a thin wall and diameter measuring 2-4 mm. Experiments (25) on a vascular channel model showed that the system provides for a 3.5 l/min performance and does not cause damage to the formed elements of the blood in operating for 240 minutes. This type of auxiliary circulation was used in 16 experiments on mongrel dogs with acute disturbance of coronary circulation (occlusion of the anterior interventricular branch of the left coronary artery (AIVB) with a balloon catheter for 60 minutes). The viability of the myocardium in the zone of the occluded AIVB was maintained and its function completely restored in the postischemic period in all cases. In the control group (5 experiments) the zone of the infarction accounted for 40 to 60% of the mass of the myocardium supplied by the AIVB. The use of the method is very promising in acute disorders of coronary circulation.

Animals↗
PubMed1990

[Criteria for the selection of patients with a single heart ventricle for anatomical correction].

The work deals with study of the functional condition of the myocardium in 34 patients with a solitary ventricle of the heart (SVH). The regional function of the myocardium was disturbed in all patients; the degree of the disturbance was determined by the anatomical variant of the SVH and was characterized by different distribution of the hypofunctioning segments in the ventricular myocardium. In view of that, to solve the problem of the possibility of accomplishing anatomical correction, the regional function in the zones of the future (after septation) ventricles must be evaluated. Radical correction may be performed with the least degree of risk in patients in whom the ejection fraction in each of the new ventricles will be greater than or equal to 55%. In the group of 17 patients only 5 conformed to this criterion.

Child↗
PubMed1990

[Epicardial destruction of the bundle of Kent by pulsating electric current and the criteria of its effectiveness in Wolff-Parkinson- White syndrome].

The article deals with a new method of treatment of the Wolff-Parkinson-White syndrome. The operation for epicardial destruction of Kent's bundle by pulsating current was developed by the authors. It is distinguished by its simplicity and the possibility to determine the efficacy of the procedures during the operation itself. The results of examination of 44 patients in the early postoperative period and in late-term periods after this operation are discussed. It was found that the electric factor does not cause structural changes of the underlying structures and does not affect the pumping function of the myocardium. The revealed changes were recorded by means of angiocardiography, coronarography, radionuclide ventriculography, and the enzyme spectrum.

Adolescent↗
PubMed1990

[Changes in cardiac hemodynamics, volume and pumping function of the heart ventricles in natural course of Fallot's tetrad].

The work analyses the results of repeated clinical and intracardiac examination of 13 patients with tetralogy of Fallot, conducted at the age of 23.1 +/- 9.9 and 42.3 +/- 13.1 months. The severity of the clinical condition grew markedly during natural course of tetralogy of Fallot (TF): the SaO2 value reduced from 71.8 +/- 7.2 to 65.0 +/- 8.0% and the blood hemoglobin level grew from 165 +/- 28 to 194 +/- 30 g/l. The data presented are evidence that in TF following a natural course a distinct tendency is displayed to growth of end diastolic volume of both ventricles in relation to the normal value and their dysfunction progresses in the form of reduction of the ejection fraction and increase of right-ventricular diastolic "rigidity". The results of the present work may be considered a substantiation of the tactics of early TF correction in infants and young children before the development of serious morphological changes and functional disorders.

Cardiac Volume↗
PubMed1990

[Regional and general left-ventricular functions after reconstructive operations and prosthesis of the mitral valve].

The authors used an original method to study the general and regional function of the left ventricle of the heart in patients in the late-term periods after complicated reconstructive operations and mitral valve prosthetics. In patients of the second group increased volumes of the heart were maintained, diminished left ventricular ejection fraction and marked disorders of function in the basal segments were revealed which the authors believe to be caused by excision of the chordo-papillary++ apparatus of the mitral valve and firm fixation of the fibrous ring by the cuff of the prosthesis. These disorders were not encountered in patients who underwent reconstructive interventions which in the presence of the appropriate indications should be the operations of choice because they facilitate fuller restoration of left ventricular function in the late-term periods after surgery.

Adult↗
PubMed1989

[Quantitative evaluation of hypoplasia of the heart ventricles and its significance for heart surgery].

The quantitative anatomy and morphology of hypoplastic ventricles were studied in 28 afflicted hearts (15 with left ventricular hypoplasia, 13 with right ventricular hypoplasia). The control comprised 10 normal heart specimens. All the 38 specimens were studied morphometrically; this was complemented with angiocardiometry and ventricular volume estimations in diagnosing right ventricular hypoplasia. Based on the study results, the morphometric criteria of ventricular hypoplasias and their variant forms were established. The linear characteristics were found to be informative enough both in hypoplasia diagnosis and in its degree assessment. To choose a therapeutic method, two degrees of right ventricular hypoplasia were distinguished. Radical correction aimed at eliminating concomitant conditions was found to be feasible and performed in 27 patients with moderate right ventricular hypoplasia.

Heart Defects, Congenital↗
PubMed1989

[Clinical characteristics of the Soviet low-profile heart valve prostheses EMIKS and LIKS].

The present work is devoted to the clinical assessment of the Soviet-made cardiac valve prostheses 'EMIKS' and 'LIKS'. From 1983 to May 1, 1988, 632 prostheses were implanted to 508 patients. A group of 348 patients were assessed: 139 after mitral (M) replacement, 130 after aortal (A) replacement, and 79 after mitral-aortal (M+A) replacement. Hospital mortality rate was: in M group--4.3 per cent, in A group--5.3 per cent, in M+A group--8.8 per cent. Survival rate on the fifth postoperative year was: in M group--89.5 +/- 9.2 per cent, in a group--90.0 +/- 4.2 per cent, in M+A group--91.0 +/- 6.2 per cent, the stability of the good results being 85.5 +/- 7.2, 79.5 +/- 6.2, and 75.0 +/- 9.1 per cent, respectively. At year 5 of the follow-up, patient numbers without thromboembolic complications amounted to 95.0 +/- 4.7 per cent in M group, 95.5 +/- 4.2 per cent in A group, and 85.0 +/- 9.1 in M+A group. 95.1 per cent patients belong to functional classes I and II. In mitral replacement, the mean 'EMIKS' gradient was 4.2 +/- 0.58 mm Hg, the 'LIKS' one--4.58 +/- 0.62 mm Hg. Intravascular hemolysis was not observed. The 'EMIKS' and 'LIKS' prostheses match the models produced in other countries. No significant differences between the two models were found.

Aortic Valve↗
PubMed1989

[General and regional functions of the right ventricle in idiopathic ventricular arrhythmias].

Various aspects of the diagnosis of idiopathic ventricular arrhythmias, seen in cases where no heart changes can be detected by noninvasive investigation are discussed. Total and regional right-ventricular myocardial activity was assessed in 10 patients with moderate idiopathic right-ventricular arrhythmias. All patients underwent electrophysiologic investigation with endocardial mapping and right ventriculography. In 9 cases, biopsy from unexamined arrhythmogenic zones was taken intraoperatively for histologic studies. Arrhythmogenic foci were located in the right-ventricular outflow department in most cases of idiopathic ventricular arrhythmias. The outflow and inflow right-ventricular departments commonly demonstrated regional myocardial dysfunctions and disordered sequence of contractions of the appropriate myocardial portions during intermediate intervals of the ejection phase.

Adolescent↗
PubMed1988

[Effect of the rheological properties of the blood on the intracardiac hemodynamics in patients with acquired mitral valve defects].

A study of 17 patients with prevailing mitral stenosis and 10 patients with prevailing mitral insufficiency demonstrated a significant aspirin-induced improvement of blood rheologic characteristics in all patients that was accompanied with a heterogeneous shift of intracardiac hemodynamics and left-ventricular myocardial pumping activity. For instance, in patients with prevailing mitral stenosis, an improvement of blood rheologic properties is accompanied with a drop in mitral pressure gradient and a decrease in total pulmonary resistance and total peripheral resistance resulting in increased pumping capacity of the heart (increased minute volume, systolic index and stroke index). In patients with prevailing mitral insufficiency, the improvement of blood rheologic properties is accompanied by an increase of regurgitation volume, a reduction of effective ejection fraction and a rise in total pulmonary resistance. Therefore, a differential approach to the use of agents improving blood rheologic properties is needed.

Adult↗
PubMed1985

[Myocardial regional contractile function of the right ventricle].

On the basis of the angiocardiographic examination of 22 individuals without cardiovascular diseases or suffering from congenital heart disease with mild hemodynamic changes, the authors devised the method for assessing the regional contractile function of the right ventricle myocardium founded on the anatomical principle of the division of the right ventricle chamber into different portions. The possibility of the quantitative evaluation of the functional status of different portions of the right ventricle is demonstrated.

Adolescent↗
PubMed1981

[Method of postmortem determination of heart chamber volume].

A new method for postmortem determination of volumes of heart chambers has been developed which reflects their vital volume most accurately. Volumetric values of heart chambers have been calculated by comparison of mathematically calculated vital volumes with postmortem ones.

Autopsy↗
PubMed1981

[Age norms of the volumetric indices of the heart chambers].

The age volumetric norms of heart chambers were determined by the method developed by the authors. The dependence between the degree of myocardial hypertrophy and the increase of the volume taken by intraventricular trabecular apparatus as well as the dependence of systolic and diastolic regression coefficients in calculation of heart chamber volumes from the intravital angiocardiogram upon the absolute volume occupied by the intraventricular trabecular apparatus were detected.

Aging↗