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Biomedical subjects

N A Collop

Publications and source records attributed to N A Collop.

25 records · Page 2Linked to original sources
PubMed1993

Critical illness in pregnancy. An analysis of 20 patients admitted to a medical intensive care unit.

There is a paucity of literature with regard to the need for intensive care treatment of critically ill obstetric patients. In this review, the findings from 20 obstetric patients admitted to a medical ICU (MICU) over a 40-month period were analyzed. Demographics, preexistent medical problems, diagnoses, days in the hospital and the MICU, need for mechanical ventilation, maternal and fetal mortality, and invasive procedures were reviewed. (For comparison, a limited analysis of nonobstetric admissions to the MICU over the same time period were included.) Fifty percent (10) of the patients had preexisting medical problems. Maternal mortality was 20 percent (4 patients), with a fetal mortality of 35 percent (7). In all of the maternal deaths, adult respiratory distress syndrome was present. Although mortality and the need for mechanical ventilation did not differ between the obstetric and nonobstetric patients, pulmonary artery and arterial catheters were placed at a higher rate in the obstetric patients. Critically ill obstetric patients, although younger than general MICU patients, appear to have as great a risk of dying of their critical illness and have a high infant mortality.

Adolescent↗
PubMed1991

Pharyngeal volume in asymptomatic snorers compared with nonsnoring volunteers.

STUDY OBJECTIVE: to determine if asymptomatic snorers have smaller pharyngeal volumes than age- and height-matched nonsnorers. DESIGN: we recruited asymptomatic heavy snorers and nonsnorers for a study. Each snorer was matched by age (+/- 3 years) and height (+/- 2 inches) with a nonsnorer. The nonsnorers were required to be near ideal body weight. All volunteers underwent overnight polysomnography, pulmonary function testing, and magnetic resonance imaging of the pharynx while awake. The volume of the pharynx was determined by a computer with data input from a digitizing instrument. SETTING: Veterans Administration Hospital and University of Florida Teaching Hospital PARTICIPANTS: Nine volunteers were recruited for both the snorer and nonsnorer groups. Each participant was paid $50. There were no interventions. MEASUREMENTS AND RESULTS: There were no differences in sleep variables between the two groups. There was also no significant difference between pharyngeal volumes for the two groups. CONCLUSIONS: The volume of the pharynx in asymptomatic snorers is similar to the volume in age- and height-matched nonsnorers.

Adult↗
PubMed1991

The effect of nightly nasal CPAP treatment on underlying obstructive sleep apnea and pharyngeal size.

Nasal continuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep apnea (OSA). It is usually prescribed for nightly use; however, recent studies show that patients often do not wear the appliance consistently. Previous studies have also suggested that nasal CPAP may improve a patient's underlying OSA even when the mask is not in place. We investigated 12 men with OSA to see if nasal CPAP used nightly for six weeks would improve their underlying sleep-disordered breathing. We also studied pharyngeal volumes measured using magnetic resonance imaging and a computer-controlled digitizing pad. Patients with more severe OSA had improvement after six weeks; however, they still demonstrated significant OSA. Patients with less severe OSA did not have significant change. We were unable to show a significant difference in any patient's awake pharyngeal volumes. We conclude that patients with OSA should be encouraged to wear their nasal CPAP machines regularly.

Humans↗
PubMed1990

A solitary pulmonary nodule due to Mycobacterium gordonae.

Mycobacterium gordonae is rarely pathogenic in humans. In this case it was cultured from the tissue of a resected pulmonary nodule in an immunocompetent patient. One year after completing 12 months of chemotherapy, the patient remains disease free. Atypical mycobacterium should be considered in the differential diagnosis of solitary pulmonary nodules.

Aged↗
PubMed1990

Pulmonary problems in pregnancy.

Pregnant women with asthma and pulmonary infections should be treated essentially the same as nonpregnant women with similar disease severity. Definitive diagnosis and prompt treatment with heparin should be used for patients with pulmonary thromboembolism.

Asthma↗