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N A Epstein

Publications and source records attributed to N A Epstein.

8 recordsLinked to original sources
PubMed1976

Prostatic carcinoma: some morphological features affecting prognosis.

Morphologic features in 146 cases of prostatic carcinoma were correlated with 5-year survival. Simple probability tests showed a significant prognostic difference of the presence or absence of cell borders, lymphocytic infiltration, pleomorphism of nuclei, and McNeal's typing. Further statistical analysis, with a probability test which was adjusted for the distribution of these factors, showed that only the presence or absence of cell borders and lymphocytic infiltration affected prognosis. It is very important for the pathologist reporting on prostate carcinoma to include mention of these factors in his report because of their prognostic importance. In particular it should be noted that if the tumor has indistinct cell borders and there is no lymphocytic infiltration, then it is likely to have a very poor prognosis.

Adult↗
PubMed1976

Prostatic carcinoma. Correlation of histologic features of prognostic value with cytomorphology.

Positive aspiration smears of 34 cases of histogically confirmed prostatic carcinoma were studied. Four features found to be of prognostic value in histologic material in a previous study--cell borders, lymphocytic infiltration, pleomorphism, and histologic typing of the tumor--were compared with the cytologic pattern present on the smears. Pleomorphism was the only feature for which good correlation was obtained between these two techniques. Unfortunately, the grade of pleomorphism is not reproducible from one observer to another. Cell borders, when present in groups of malignant cells in the smears, were also present in the sections. The absence of this feature in the smears did not imply absence in the sections.

Humans↗
PubMed1976

Prostatic biopsy. A morphologic correlation of aspiration cytology with needle biopsy histology.

One hundred and eighteen aspiration biopsies of the prostate are correlated with needle biopsies. The overall accuracy of the needle biospy is 85.6% and that of the aspirates is 86.6%. The author recommends that both techniques should be used simultaneously in the diagnosis of carcinoma of the prostate. Descriptions are given of benign and malignant cell types in prostatic aspirates, with special emphasis on the features differentiating benign atypia of prostatic cells from well-differentiated adenocarcinoma, as this is potentially an important source of false-positive reports in aspiration smears.

Aged↗
PubMedDate not supplied

Primary papillary carcinoma of the prostate: report of a histopathologic, cytologic and electron microscopic study on one case.

An unusual type of prostatic carcinoma is described. Histopathologic examination showed a papillary and acinar appearance. Aspiration cytology showed papillary fragments and sheets of malignant cells. The ultrastructural features of this tumor were similar to those reported for prostatic carcinoma rather than endometrial carcinoma supporting a prostatic orgin for this tumor.

Aged↗