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Biomedical subjects

N A Khitrov

Publications and source records attributed to N A Khitrov.

9 recordsLinked to original sources
PubMed2005

[Structure of osteoarthrosis diseases and the problem of concomitant diseases].

AIM: To study pattern of osteoarthrosis (OA) morbidity, OA age and gender characteristics; to analyse affection of the para-articular tissues in gonarthrosis (GA), GA concomitant diseases in outpatient settings. MATERIAL AND METHODS: OA detection and concomitant diseases were studied in the outpatient department with computer informative system. ICD (10 revision) was used in classification. Results. OA morbidity was 6.2%. Male to female ratio was 1:2.6. Incidence rate of paraarticular tissue lesions in exacerbation of GA rose 2.5 times. In GA patients concomitant diseases were registered 1.7 times more frequently than in other outpatients, while obesity, hypertension, ischemic heart disease occurred 2 times more frequently. CONCLUSION: OA as disease of accumulation was confirmed in older patients. Old age conditioned more frequent concomitant diseases. This determines polymorbidity of clinical manifestations and requires an individual approach to the patients.

Adult↗
PubMed2003

[Dynamic changes in synovitis activity after intra-articular administration of xefocam in patients with rheumatoid arthritis (according to clinical and device examinations)].

AIM: To assess efficacy of intraarticular administration of lornoxicam (xefocam) in patients with rheumatoid arthritis (RA). MATERIAL AND METHODS: Xefocam was injected into the knee joints of 58 patients with RA once a week for 3 weeks in a dose 8 mg. The treatment efficacy was evaluated by changes in the severity of arthralgias, pain in the joints at palpation, circumference of the knee joints at the level of the upper edge of the patella, ultrasound and thermography of the knee joints. RESULTS: Xefocam relieved arthralgia (in 44 patients at least by 30%), pain in the joints at palpation and joint circumference. Ultrasound investigation registered a significant thinning of the synovial membrane and amount of exudates. CONCLUSION: If local steroid therapy is not definitely indicated, intraarticular administration of xefocam can be effectively used for suppression of moderate inflammation in the joints in RA patients.

Adult↗
PubMed2000

[Osteoarthrosis].

Explore the source record for details and available documents.

Analgesics↗
PubMed1997

[A comparative evaluation of local therapy methods in treating osteoarthrosis deformans].

71 patients with knee joint osteoarthritis deformans in exacerbation with weak exudative component have received outpatient treatment: intrajoint injections of kenalog with novocaine, jet intra- and periarticular injections of the above drugs, magnetolaser therapy (groups 1, 2 and 3, respectively). The response was obtained in 85, 90 and 75%, respectively. Neither toxicity nor complications were recorded. The above methods are recommended for use in outpatient departments and clinics.

Aged↗
PubMed1993

[The treatment of osteoarthrosis deformans by needle-jet intra- and periarticular drug injections].

The paper reports pilot experience with jet needle drug injections for knee joint osteoarthrosis deformans running with proliferative involvement. The treatment was performed outpatiently in the disease exacerbations associated with reactive synovitis. Injections of 20 mg kenalog were made with the semiautomatic combined jet injector ISI-I. 24 patients received 71 injections (a mean of 2.1 injections, each). Basic therapy underwent no changes. The course of injections produced improvement in 21 patients (87.5%). The majority of them got better as early as the first injection: arthrosis symptoms and pain alleviated, joint hyperthermia reduced, the mobility, on the contrary, increased. Blood counts showed no negative trends. Complications and exacerbations due to the treatment were not reported. Because of the efficacy, easy performance, painlessness, jet intra- and periarticular injections are believed beneficial and can be used outpatiently.

Aged↗
PubMed1986

[Use of a computer-assisted electrocardiograph for electrocardiographic control of pulse therapy].

A study was made of the effect produced by a short course of treatment with large doses of corticosteroids and cyclophosphamide on the ECG in patients with different rheumatic diseases before, during and after pulse therapy. The study was performed with the aid of a computer-aided electrocardiograph IKS 6000. No changes were recorded on the part of automatism and conduction of the heart muscle. Twenty-nine patients (85%) manifested changes in the amplitude of the T waves during pulse therapy. Of them 16 demonstrated a reduction whereas 13 an increase in the amplitude of the T waves. Out of 8 patients, who received cyclophosphamide in addition to hormones, 6 showed a decrease in the amplitude of the waves, which attested to the effect of the treatment on myocardial metabolism.

Adolescent↗