PubMed Health⌕ Search

Biomedical subjects

N A Kravchenko

Publications and source records attributed to N A Kravchenko.

At least 19 recordsLinked to original sources
PubMed1989

[Problems and prospects of improving hospital care planning in the USSR].

The necessity of planning the hospital network (bed capacity and its structure) in combination with social security institutions is validated. Thus, planning of the hospital network should be carried out in combination with social security institutions, the degree of development of other forms of medical services (hospitals at home, day hospitals, curative and diagnostic complexes, etc.) being taken into account. By preliminary estimates the demand for hospital beds is 127 per 10,000, 13 for chronic patients and the elderly in medicosocial facilities, 38.9 in social security institutions. Realization of the principles of differentiated hospital treatment of patients according to the degree of its intensity enables one to use hospital resources more effectively and to raise the quality of inpatient care. It is recommended to differentiate specific investments in hospital construction (25,000-70,000 rubles per a bed) according to the demand in hospital beds at different stages of treatment intensity and hierarchial level of medical care organization. Equal possibilities in the provision of inpatient care for the whole population can be achieved within the framework of unified regional models of the network of health care facilities, based on the standard target approach to the utilization of hospital resources.

Aged↗
PubMed1981

[Characteristics of the effect of egg lysozyme on micrococci and staphylococci].

The nature of the optical density of suspensions of Staph. aureus and M. luteus cells at various concentrations of chicken egg albumin lysozyme and two products of its chemical transformation was studied comparatively. The experiments were performed in 1/15 M Na-phosphate buffer at pH 6.2 and a temperature of 20-22 degrees C. It was shown that the decrease in the optical density of the suspensions observed at relatively low concentrations of lysozyme, i.e. 0.032-0.064 mg/ml, was due to lysis of both microbial species. The increase in the optical density of the suspensions at higher (0.5-2.0 mg/ml) concentrations of lysozyme was connected with formation of insoluble aggregates of an electrostatic character. Lysozyme in such aggregates is the positively charged component and the microbial cell material is the negatively charged component. When M. luteus strains are sensitive to lysozyme, the aggregates are formed from the cell fragments or lysis acid products. When Staph, aureus strains have higher resistance levels, the aggregates are formed from both the lysis products and the intact live cells which is of special interest.

Acetylation↗
PubMed1979

[Action of egg lysozyme on representatives of the family Micrococcaceae. The action on staphylococci].

The results of the study on the effect of various concentrations of lysozyme on staphylococci of three species, i.e. Staphylococcus aureus, Staphylococcus epidermidis and Staphylococcus saprophyticus are presented. The study was performed with the use of the turbidimetric method. It was found that all the staphylococci had a common tendency for changing the optic density (OD) of the suspensions under the effect of lysozyme which was different from that in Micrococcus luteus. However, the dynamics of decreasing the OD in Staph. saprophyticus was characterized by some properties which provided a supposition that the structures of the cell walls in Staph. aureus and Staph. epidermidis were close, while the cell walls in Staph. saprophyticus had some unknown characteristics.

Dose-Response Relationship, Drug↗