Picture of the month. Amyoplasia congenita.
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Biomedical subjects
Publications and source records attributed to N A Kulaylat.
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OBJECTIVE: Study of the incidence of childhood type 1 diabetes in the Eastern Province of Saudi Arabia. METHODS: Analysis included all children eligible for care in our hospital who had type 1 diabetes diagnosed before their 15th birthday between 1986 and 1997. RESULTS: A total of 46 children (27 girls and 19 boys) were identified, with a median age at diagnosis of 10.3 yr. The overall age-adjusted incidence rate was 12.3 x 10(5)/yr; it was 9.9 x 10(5)/yr for males and 14.8 x 10(5)/yr for females. The number of patients increased significantly (relative risk of 46) over the study period (p=0.01), more significantly in females (p=0.007) and in the 10-14 year age group (p=0.01). CONCLUSIONS: The incidence of type 1 diabetes increased markedly over the past 12 years, mainly in females and children over 10 years of age. The data confirm the need to develop a national registry and the need for further epidemiological research.
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OBJECTIVE: To determine the incidence of antenatal and intrapartum maternal and fetal complications of gestational diabetes mellitus (GDM) and compare them with pre-gestational diabetes mellitus (pre-GDM) and non-diabetic pregnancies in our population. STUDY DESIGN: Nine-hundred and seventy-two women with gestational diabetes mellitus and 71 women with pre-gestational diabetes mellitus, and their offspring (delivered in our hospital between January 1991 and April 1994) were studied. Maternal and fetal prenatal and intrapartum complications were analyzed. RESULTS: The incidence of GDM was 9.8%. The maternal complications included higher incidences of cesarean section and perineal lacerations in GDM and pre-GDM patients than in the non-diabetic pregnancies, and higher rates of macrosomia and hypoglycemic episodes in their offspring. CONCLUSION: The incidence of maternal, fetal and neonatal complications in GDM is similar to pre-GDM patients and their offspring. Both GDM and pre-GDM pregnancies and the offspring should, therefore, be monitored and managed identically.
Eighteen children with infective endocarditis were detected over seven years. Fever, gastrointestinal and chest symptoms were striking features. Anaemia, elevated leukocyte count and sedimentation rate were constant laboratory findings. Strep. Viridans and Staph. Aureus were the commonest organisms isolated. We concluded that rheumatic and congenital heart disease are equally important in predisposition to infective endocarditis.
Twelve sick neonates, ten of whom were prematures, were found to have transient primary hypothyroidism. Two months after cessation of treatment all those followed were found to be clinically and biochemically euthyroid. The possible etiologic factors in the pathogenesis of transient hypothyroidism of the sick prematures are discussed. Iodine deficiency is probably an important precipitating cause.