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N A Nechiporenko

Publications and source records attributed to N A Nechiporenko.

34 records · Page 2Linked to original sources
PubMed1978

[Ways to improve the early detection of bladder cancer patients (based on Grodno Province data)].

The authors present an analysis of the data on 281 primarily recognized patients with cancer of the urinary bladder in Grodno Province 1968--1974. Among all these patients 49.5% were recognized 1 year and longer following the initial clinical manifestations of the disease. In every fifth case there was a far-advanced process. The causes of late recognition are as follows: underestimation of a tainsiet hematuria by patients, and in a number of cases the absence of oncological vigilance among general practitioners in the treatment of patients showing hematuria. To improve the early diagnosis of the bladder cancer, it is suggested to differentiate cancer high-risk groups. This contingent should be periodically examined by a specialist with prophylactic purposes. Moreover, an attention is paid to the necessity of a detailed urological examination of all persons with hematuria, or who showed it previously.

Adult↗
PubMedDate not supplied

[Simultaneous operations for combined surgical diseases in urological practice].

The study covered 653 patients with a combination of two surgical urological diseases or one urinary disease with one abdominal disease. Simultaneous operations were made in 409 patients, staged surgical treatment was performed in 154 patients who rejected one stage treatment. Simultaneous surgery was contraindicated because of severe associated diseases in 90 patients. Short-term results showed that simultaneous elective operations are characterized neither by increased frequency of postoperative complications nor longer stay of the patients in hospitals. Medical, psychological and cost-effective benefits of simultaneous operations in the treatment of combined surgical pathology make simultaneous operations promising for wide clinical practice.

Adult↗
PubMedDate not supplied

[The dispensary care and work disability expertise of bladder cancer patients following cystectomy].

A question of the principles and methods of medical prophylactic survey in patients with bladder cancer who have undergone cystectomy with subsequent ureterosigmoid anastomosis and ureterocutaneostomy is not currently developed. On a basis of 79 follow-ups of patients with bladder cancer after cystectomy, a procedure of prophylactic survey in the setting of regional oncologic dispensary and district polyclinic was worked out. It is stressed that it is necessary to follow up the patients for a possible relapse and metastasis development as well as complications of the upper urinary tract and kidneys and metabolic shifts (acidosis, dyselectrolytemia). From this viewpoint we propose a scope of essential examinations during the medical prophylactic survey. Our results of the patients follow-ups after cystectomy are also given. Recommendations for the patients working ability estimation are proposed and it is noted that the estimation is to be carried out on a strictly individual basis because the patient's rehabilitation depends on many factors. But the main principles of such patients' working ability estimation are submitted in schemes of a working ability examination. They depend on the stage of the process and on the method of urine drainage after cystectomy.

Ambulatory Care↗
PubMedDate not supplied

[The free amino acid content of the blood serum in bladder cancer patients].

The content of 18 amino acids in the blood serum was studied in 57 patients with T2-4 carcinoma of the bladder according to the stage of the process and the functional condition of the kidneys. Dysaminoacidemia was found in patients with T2 bladder carcinoma, which did not need correction; marked hypoaminoacidemia was encountered in stage T3-4 tumors. Chronic renal insufficiency (intermittent and terminal stages) is conductive to significant decrease of the blood amino acid level. The content of amino acids is lower in the postoperative than in the preoperative period. The degree of reduction of the amino acid content in blood was found to be dependent on the volume of the operation. The reduction of the amino acid content is more intense after cystectomy than after resection of the bladder. Correction of the blood amino acid content in the preoperative period in patients with T3-4 carcinoma of the bladder reduces the incidence of postoperative complications. Correction of hypoaminoacidemia with polyamine proves effective in patients with maintained renal nitrogen excreting function. In development of azotemia in patients with bladder carcinoma, substitution transfusion therapy for correction of hypoaminoacidemia becomes effective only after restoration of the nitrogen excreting function of the kidneys.

Aged↗
PubMedDate not supplied

[Causes of the functional disorder of the kidneys in patients with bladder cancer after cystectomy with ureterosigmoid anastomosis].

Cystectomy with ureterosigmoid anastomosis by modified Goodwin's technique was performed in 47 patients with local vesical cancer. Pre- and postoperative functional status of the kidneys was assessed by means of renography, excretory urography and laboratory tests. Unilateral or bilateral renal dysfunction developed within 12 to 18 months after surgery in 22.2% of patients with good pretreatment renal status. In cases of preoperative renal impairment, it improved postoperatively in just 35% of the patients. Rectoromanoscopy, contrast sigmoidography and excretory urography demonstrated pathological conditions in the area of ureterointestinal anastomoses (strictures, gaping or anastomositis) or sigmoid changes (sigmoiditis, kinking or stenosis in the perianastomosis area) in 83.3% of patients with impaired postoperative renal function. These conditions lead to hydroureteronephrosis, intestinoureteral refluxes and progress or development of pyelonephritis as a result. It is concluded that the state of ureterointestinal anastomoses and the sigmoid should be assessed specifically in postureterosigmoid anastomosis patients with impaired renal function. The surgical techniques and the degree of ureteral dilatation can make an important contribution to pathologic conditions developing around the anastomoses. Good functional activity of the kidneys and the absence of upper urinary dilatation are the principal prerequisite for ureterosigmoid anastomosis.

Adult↗