[Structure and ways of lowering disability after burns].
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Biomedical subjects
Publications and source records attributed to N A Ponomareva.
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The morphology of chromatin in spontaneously ovulated rat's oocytes was investigated. The degree of chromatin condensation was shown to vary widely: along with the typical cytological picture of metaphase II, both highly condensed (clamped) and decondensed ("not typical") forms of chromosomes were observed. A direct relation was discovered between the prevalence of the not typical morphological forms of oocyte chromosomes and the level of embryonal death. The shape of clamped and decondensed forms increased in the oocytes from old rats and in post-ovulatory aged oocytes.
The correlation of the intrapartum blood coagulability and the amount of postpartum blood was followed up. Blood coagulability was assessed with electric coagulography and the blood loss amount, with gravimetry. It was found that pathological postpartum blood loss occurred in the females whose labor onset was distinguished by the predominance of hypercoagulation with its subsequent intrapartum decrease. Therefore, insignificant (less than 9 per cent) increment in the blood coagulability during the labor can be regarded as a prognostic sign of pathological postpartum blood loss.
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The paper is devoted to an experimental evaluation of the efficiency of hypoxiradiotherapy with irradiation of tumors by protons at different dose rates. In experiments performed at ITEP synchrotron it has been shown that the use of the hypoxic gas mixture containing 6% O2 for breathing appreciably diminishes the degree of skin reactions with only weak tumor protection. It is concluded that the use of hypoxic hypoxia during proton irradiation afford the same advantages as during gamma- or x-ray therapy. The skin protection can be also achieved by use of ultra-high dose rate and in this case it is associated with radiochemical depletion of oxygen. This effect may be used for the improvement of radiotherapy of malignant tumors.
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Twenty six girls with deep burns of the anterior and lateral surface of the chest were treated in Gorky Research Institute of Traumatology and Orthopedy. The obserrvations indicated that an early closure of burn wounds in this region with adequate skin grafts could prevent gross deformity of mammary glands. Moreover, 70 females with deformation of mammary glands were under observations. In 16 of them operative procedures were undertaken for isolated lesions of 22 mammary glands. Various methods of skin plasty were employed: local, free, combined. Good and satisfactory results were gained. In 54 female patients deformities in the region of 68 mammary glands were eliminated simultaneously during surgical procedures for cicatricial contractures of the brachial joint, coxa and neck. The results obtained are described.
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