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Biomedical subjects

N A Skuia

Publications and source records attributed to N A Skuia.

At least 19 recordsLinked to original sources

[T-lymphocyte subpopulations in chronic pancreatitis].

A possibility to diminish the number of recurrences in chronic pancreatitis by using delagil (chloroquine) was shown during investigation of the status of cell-mediated immunity in chronic pancreatitis. The paper is concerned with the results of the determination of the ratio of theophylline-resistant T-cells (helpers) to theophylline-sensitive T-cells (suppressors) in the peripheral blood. The H/S ratio was determined in 49 patients with different patterns of chronic pancreatitis and in 20 controls. Enhanced (greater than or equal to 5) and low (less than or equal to 1.5) indices were characteristics of an unfavorable course of the disease. The H/S ratio is recommended for clinical use in pancreatology for prognostic purposes and to define the need of immune modifying therapy.

Adult↗

[Prognosis of chronic stomach ulcer according to the results of gastrochromoscopic morphologic evaluation of the gastric mucosa].

Histochemical studies with Congo red (to determine the size of an acid forming area) and methylene blue (to detect enterolization foci) were carried out in 46 and 45 patients with chronic ulcer in the stomach body, respectively. Gastrobiopsy specimens from the fundal and pyloric gland portions were subjected to a morphological study. A follow-up over a course of disease showed prognostically unfavorable significance of the acid forming area value exceeding 1/6 of the stomach area, the presence of unchanged gastric mucosa in these portions and the absence of enterolization foci with respect to both cicatrization and frequent recurring of the ulcer crater. The spreading and deepening of gastric changes in the gastric mucosa were regarded as sanogenetic factors in patients with chronic peptic ulcers.

Adult↗