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Biomedical subjects

N A Wani

Publications and source records attributed to N A Wani.

At least 19 recordsLinked to original sources
PubMed1991

A study of colorectal adenocarcinoma.

One hundred and seven patients with resected colorectal adenocarcinoma were studied between 1983 and 1987. These formed 3.3% of all cancer cases and 19.4% of gastrointestinal malignancies seen during the period. A majority of patients (68.7%) were between 41 and 60 years of age; 31.8% were below the age of 40 years. There was a male preponderance (62.6%). Left sided cancers were more common (65.4%). The predominant histologic patterns were well differentiated adenocarcinoma (72%) and mucinous carcinoma (20.6%). Mucinous carcinoma was more common on the left side. A majority of cases (95.3%) were in Duke's stages B and C. Only 2.8% of cases were confined to the mucosa.

Adenocarcinoma↗
PubMed1989

Pre-operative and post-operative evaluation of circulating immune complexes in patients with gastric adenocarcinoma.

Circulating immune complexes (CICs) in the sera of patients with histologically proven adenocarcinoma of stomach were sequentially studied. Serial CICs levels, quantitated using a sensitive method F(ab')2 anti-C3 ELISA, were measured before surgery and in a post-operative follow up. CICs could be detected in 85% of the patients pre-operatively, while ten days after surgery positivity decreased to 71%. Thirty days after surgery, the mean CIC levels decreased significantly and positivity fell to 46%. The results indicate that removal of primary tumor mass results in a sharp decline of CIC levels.

Adenocarcinoma↗
PubMed1989

Leiomyoblastoma stomach.

Three patients with epithelioid leiomyomatous tumors (leiomyoblastomas) of the stomach are presented.

Adult↗
PubMed1989

Primary carcinoma of gall bladder--a review of thirty six cases.

The study presents the clinicopathological findings in thirty six cases of primary carcinoma of gall bladder diagnosed at SKIMS Srinagar over a period of four years (1983-86). Particular attention was paid to age, sex, presenting symptoms, presence of gall stones and site of metastasis. Majority of patients were found to be middle aged females (24 out of 36 cases). Most common presenting symptom was abdominal pain and duration of symptoms was two months or less in majority of cases. Gall stones were found in 55.5% cases. Diagnosis of primary gall bladder carcinoma was an incidental histopathological finding in 22% patients. Well differentiated adenocarcinoma was found to be the commonest type of malignancy (77.7%). 33% cases had widespread metastatic disease at the time of operation and liver was the commonest site of invasion (47.2%). Follow up records of 21 out of 36 patients available show only two patients to be alive till date with more than two year follow up and in both these cases carcinoma was an incidental histopathological diagnosis at cholecystectomy. Rest of the patients had died within 5-6 months after surgery. This reinforces the poor outcome for primary gall bladder carcinoma patients irrespective of treatment unless diagnosed and treated at a very early stage. Long term survival can be expected in incidentally found carcinoma at cholecystectomy.

Adult↗
PubMed1977

Evaluation of bacteria and biliary tract diseases.

Bile specimens were taken for culture from 100 patients who had disease originating in the biliary tract. Routine cases of chronic cholecystitis with cholelithiasis were found to have a low incidence of infected bile. An acute process appears to be needed in order to produce infected bile, and an acute obstruction of the bile duct due to gallstones produced infected bile. An effort should be made to select these patients and begin antibiotic therapy as soon as possible.

Adolescent↗