[Present-day concept of splenectomy in chronic myeloleukemia (review of the literature)].
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Evaluation Studies as Topic↗
Biomedical subjects
N A Zakharenko
Publications and source records attributed to N A Zakharenko.
[Ammonia metabolism in tissue of newborn animals in health and in digestive disorders].
Ammonium nitrogen was studied for its metabolism in the tissues of ruminants in transition from pre- to postnatal development in norm and with disorders in gastroenteric digestion. It is established that the intensity of ammonium genesis and glycolysis processes as well as a cycle of tricarbonic acids change in newborn calves as compared to adult animals. The ammonium toxicosis development in sick animals, which is confirmed by an increase of the ammonia level and intensification of the reactions of ammonium- and ureogenesis in tissues of the gastroenteric tract, liver and kidneys.
Aging↗
[Electrolyte composition of cow and calf tissues in health and in acute digestive disturbances].
Sodium, potassium, calcium, magnesium, manganese, zinc and chloride contents in the blood plasma of calves at parturition have been established to correspond to their levels in blood of cows during their calving period. Iron and inorganic phosphorus contents in calves blood plasma appeared to increase and copper content to be lower in this period as compared to postnatal period. By the third day of postnatal ontogenesis sodium concentration in calves blood decreased, copper level increased and the rest indices of water-salts metabolism in calves and adult animals were alike. Digestion disturbances in the calves were accompanied by changes in levels and magnitude of Na+/K+ ratio, magnesium, iron, copper, manganese and zinc contents in blood, liver and kidneys as well as Ca++/Pi ratio in mitochondria and cytosol of liver and jejunum mucose layer cells in comparison with clinically healthy animals.
Acute Disease↗
[Acid-base status of the blood and adenine nucleotide metabolism in ruminant erythrocytes during early post-natal development].
It has been established that data of acid-base balance in cows' and newborn calves' blood closely correlate with physiological status of animals during their initial days of postnatal ontogenesis and depend on the peculiarities of metabolism in fetus and newborn organisms. Data on the acid-base balance in blood of newborn calves under diarrhea syndrome are discussed from the point of view of the influence of rehydration therapy and "Namacit" preparation on clinical status of animals.
Acidosis↗
[Cell respiration intensity and redox state of NAM-coenzymes in small intestine epithelium of newborn calves in health and in diarrhea].
It has been established that mucous membrane of jejunum and stomach tissue of 3-4-day calves are characterized by high intensity of glycolytic and aerobic processes. Digestion disorders with diarrheic symptoms are accompanied by changes in levels and relations in NAD (P)(+)-dependent dehydrogenase metabolites reduction of lactate- and succinate dehydrogenases, alkaline phosphatase and gamma-glutamyltransferase activities in cytoplasm and mitochondria of proximal and distal parts of the jejunum in comparison with clinically normal animals.
Alkaline Phosphatase↗
[Seasonal changes in the mineral composition of colostrum and milk whey of cows].
It is shown that in summer the level of sodium, potassium and calcium in the colostrum and milk serum of cows for the first ten days of lactation is 1.5-2.0 times higher and the content of inorganic phosphorus lower than the analogous indices for cows in winter-spring. The concentration of iron, copper, zinc and chlorides in the colostrum and milk serum of cows in different seasons is unchanged.
Animals↗
[Seasonal changes in the levels of various metabolites and proteins in cow milk and colostrum].
The studies on lactating black-and-white cows have shown that the content of albumins as well as of lactate, ammonia and glutamate in colostrum and milk of cows is higher in winter and spring but the level of beta- and gamma-globulins, citrate and urea is lower than the analogous indices in cows in summer. The concentration of alpha-globulins, oxaloacetate, malate and pyruvate in colostrum and milk did not change with the season.
Animals↗
[Characteristics of the electrolyte balance of the blood of healthy newborn calves and calves with diarrhea].
Cows and newborn (just after the birth, and on the 1st, 3rd, 5th and 10th days after it) calves were tested for the peculiarities of the electrolyte blood composition and acid-base balance under normal and diarrheic conditions. The values of Na+/K+, Cl-/HCO3-, Pn/Ca2+ ratios in the blood serum of sick animals remain unchanged, which testifies to the deep disturbances of the water-salt metabolism in tissues.
Acid-Base Equilibrium↗
[Effect of different concentrations of HCO3- and CO2 in aquarium water on metabolism in the Cyprinus carpio L. organism].
The level of pCO2 and bicarbonates in blood and tissues of Cyprinus carpio L. increases with concentration of carbonic acid (HCO3- and pCO2), the other indices of the hydrochemical composition being constant. The value of blood pH is unchanged. In fish with a higher content of carbonic acid in blood the amount of lactate, pyruvate, oxaloacetate, malate, citrate, alpha-ketoglutarate, ammonia, glutamin, free amino acids, total and residual nitrogen rises. Simultaneously the content of urea increases in kidneys, but decrease in gills, whereas in blood and live it does not differ from the corresponding indices of fishes from the control group.
Animals↗
[Effect of preparation MP-15 on the productivity and metabolism of lactating cows].
Activation possibilities of redox and biosynthetic processes are studied for lactic cows with their ration supplemented by mineral-ammonium preparation MII-15. In the blood of cows from the experimental group the amount of a number of glycolysis, biocarboxylic cycle, ammonium nitrogen exchange products as well as activity of overamination enzymes vary as compared to control, which testifies to the stimulation of redox processes and protein exchange in tissues. Application of the MII-15 preparation is accompanied by an increase in the lactic productivity of cows by 8-10% on the average.
Amino Acids↗
[Intensity of metabolism in fish tissues with an increased level of HCO3- and carbon dioxide in their blood].
An increase in the HSO3- concentration and in the carbon dioxide level is accompanied by an increase in the glutaminase, alanine and aspartate aminotransferase activities in the liver and kidneys tissues as well as in the blood serum. The in vitro experiments show that an increased level of CO2 in the incubation medium intensifies the incorporation of 14C from I-14C lysine into proteins of the fish liver.
Alanine Transaminase↗