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Biomedical subjects

N Ars-Piret

Publications and source records attributed to N Ars-Piret.

9 recordsLinked to original sources

Morpho-functional partition of the middle ear cleft.

The observation of an inter-attico-tympanic diaphragm in the middle ear (ME) cleft and the functional histology of the mucosa lead to a concept of ME morpho-functional partition. There are two separate compartments: an antero-inferior one, principally devoted to the muco-ciliary clearance function, and a postero-superior one, more devoted to the gas exchange function. With this concept of partition the mechanisms involved in the pathogeny of "otitis media" can be better understood.

Ear, Middle↗

Preservation of cochlear function after extensive labyrinthine destruction.

We report a case of hearing preservation after removal of the semicircular canals and discuss the possible explanations for the mechanisms of preservation of hearing after removal of the labyrinth. We hope to promote the perspectives and possibilities of functional surgery of the inner ear and for tumors of the cerebellopontine angle.

Adult↗

Allograft myringoplasty.

The tympanic membrane allograft myringoplasty is used for the radical treatment of chronic middle ear disease and the repair of tympanic perforations which are sequellae of the chronic middle ear conditions. In the first part, basic principles, tissue bank and surgical procedures, are explained in detail. The second part shows that this technique ensures not only total eradication of the pathology, but is favoured by the specific morpho-, physio- and bio-compatibilities of the allograft.

Biocompatible Materials↗

Tympano-ossicular allografts: morphology and physiology.

The purpose of our work was to analyze the morphology and the physiology of the tympano-ossicular allografts used for reconstruction of the middle ear. The first section of the article concerns the removal and preservation of the allografts. We then describe the results of the morphologic observations concerning the tympanic membrane, the fibrocartilaginous ring, meatal skin, and ossicular chain. The demonstration of some characteristics of the physiology of the allograft supports the results of this study.

Ear Ossicles↗

The morphogenesis of the tympanic part of the temporal bone.

The aim of this report is to describe the relative movement of the tympanic membrane and its supporting structures during embryonic and postnatal life, leading to its final position in a vertical plane. Previous studies were based on ultra thin sections which led to changes in orientation during development being missed. The importance of the present description is to provide a baseline with which abnormal ear development in certain congenital syndromes may be compared.

Humans↗

The effects of nandrolone decanoate on rarefying bone tissue.

The effects of nandrolone decanoate on rarefying bone tissue were studied with the aid of microradiography and fluorescence microscopy in tetracycline-labelled preparations of the rabbit calcaneus and the long bones of old dogs. Osteoporosis was induced in the rabbit calcaneus by resecting of the Achilles tendon. In 20 of the 24 rabbits treated with nandrolone decanoate, the osteoporosis observed was less severe than in 8 untreated controls. Furthermore, in comparison with the controls, the signs of active osteogenesis in the treated groups increased systematically. In the old dogs, nandrolone decanoate caused a new opposition, identified by tetracycline labelling, to appear at the periphery of the medullary cavity. All the observations suggest that nandrolone decanoate has a favourable effect on osteogenetic phenomena and probably an inhibitory action on bone resorption. Consequently, nandrolone decanoate is capable of preventing or, at least, of partially correcting losses of bone mass.

Animals↗