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Biomedical subjects

N Bailly

Publications and source records attributed to N Bailly.

4 recordsLinked to original sources

[Confocal microscopy in corneal dystrophies: a comparison between confocal slit scanning (ConfoScan P2) and laser scanning microscopy (Rostock Cornea Modul-HRT II)].

BACKGROUND: The object of this work was a comparison of confocal images of corneal dystrophies made by a slit scanning microscope versus a laser scanning microscope. MATERIAL AND METHODS: Using the Rostock Cornea Modul-HRT II as a confocal laser scanning microscope the images of five patients with some epithelial, stromal and endothelial corneal dystrophies were acquired. The pictures were compared qualitatively with those taken by the slit scanning microscope "ConfoScan P2" from corresponding pathologies. Also, the images of normal corneas of ten healthy persons were acquired for a qualitative comparison. RESULTS: Confocal images from both devices were able to provide significant helpful diagnostic findings about the corneal microstructure. Essential qualitative differences between the images of both devices used were not observed. Due to the additional hardware components and the software module for image acquisition, analysis and archiving, the RCM-HRT II is favoured over the "ConfoScan P2". Nevertheless, the evaluation in favour of the RCM-HRT II has to be confined because an optimised, user-friendly enhancement, the "ConfoScan 4" is currently available. CONCLUSION: Evaluating corneal dystrophies in vivo, an equivalent utility of both technical approaches has been observed.

Adult↗

Positive illusions and mental and physical health in later life.

There are three competing conceptions concerning the relationship between positive illusions and mental health: the 'traditional' mental health model, according to which an accurate perception of the self and the world is a cornerstone of psychological well-adjustment; Taylor and Brown's Social Psychological Model on mental health, which assumes that positive illusions promote good mental health; and Baumeister's Optimal Margin Theory, which states that too much accuracy is harmful to mental health, as are exaggerated illusions. These three models were evaluated in the elderly (n = 857 retirees ages 60-95) using the youthful bias, which is the illusion of being younger than one's real age. As a whole, the Social Psychological Model obtained the strongest support. Retirees who harboured an exaggerated youthful bias (more than 15 years) reported more satisfaction with leisure time, higher self-esteem, better perceived health, and less boredom proneness than those who felt as old as they were or who, except for perceived health, entertained a moderate youthful bias (between 1 and 15 years).

Aged↗

[Melanoma and primary hyperparathyroidism].

The authors present 3 cases of melanoma associated with a parathyroid adenoma discovered by routine measurement of blood calcium levels. The melanomas were differently located and had different histological degrees. Hypercalcaemia is an infrequent complication of melanoma. According to data found in the literature, it is most often consecutive to bone metastases. The other causes of hypercalcaemia are metastatic extension of melanoma to the parathyroid glands, secretion of parathormone-related peptide (PTH-RP) and the actions of prostaglandins, vitamin D and the osteoclast-activating factor (OAF). Primary hyperparathyroidism due to adenoma has seldom been described associated with melanoma.

Aged↗

Photoallergy to hexamidine.

This report details the case of an atopic patient showing a photosensitivity caused by a hexamidine solution. Patch tests were negative but photopatch tests to hexamidine in water solution were positive, after irradiation by ultraviolet A (UVA); all control tests were negative. It is well-known that hexamidine can induce contact allergy but this case was the first reported in which UVA was implicated. This photoallergy can be explained by the structure of the hexamidine molecule, but the question is: why has there never been such a case reported before?

Adult↗