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Biomedical subjects

N Bannert

Publications and source records attributed to N Bannert.

At least 37 records · Page 2Linked to original sources

[Necrotizing enterocolitis in the newborn infant. Pathogenetic risk factors in a 3 year analysis].

In a clinical study possible risk factors causing necrotizing enterocolitis (NEC) were studied in 17 preterm infants with NEC and compared with a control group of 17 healthy preterm infants. We found a more frequent rate of blood exchange transfusions and a lower rate of breast milk feeding in patients who later developed NEC than in the control group. But there were no differences between both groups concerning factors promoting hypoxia of the gut, the number of infections, antibiotic treatment, or hyperosmolar enteral feeding. The preterm infants with NEC did not show any characteristics in history, physical examination and clinical course. These children could not be distinguished as a risk group for this illness from the newborn infant control group. Therefore, with the exception of breast milk feeding, no special prevention of the necrotizing enterocolitis can be recommended.

Birth Weight↗

[Parameters of mineral metabolism in children and adolescents in athletic training].

Changes in bone structure like chondronecrosis and osteonecrosis occurred in a group of adolescent athletes especially gymnasts. To determine the etiology calcium, inorganic phosphorus, alkaline phosphatase activity and levels of 25-OH-Vit D were investigated. Single low calcium values were present in nearly the half of the athletes. In 37% the vitamin-D-levels were depressed. Such results were found in athletes with and without changes in bone structure. A vitamin D supplementation is recommended if low vitamin D levels are found. Vitamin D deficiency is not the only reason for the disturbances of the bone. Other factors are to take in consideration like nutrition, delayed bone maturation and its consequences, and the mechanical load.

Adolescent↗

[Hypertension outpatient clinic for children and adolescents. Analysis of nearly 10 years of monitoring].

314 children with hypertension living in an urban district have been transmitted to our out patient clinic. These children were discovered by regularly performed examinations of the medical youth care since 1979. We found a secondary cause of hypertension in 2.2 per cent. Risk factors, as for example familiar disposition, hyperlipidaemia, smoking and overweight, were also analysed. A dynamic exercise-test was performed by means of bicycle-ergometry. 43 per cent of the children with elevated blood pressure in rest reacted with hypertension during exercise. Criteria for drug-therapy were the unsuccessful non-medicamentous effects on the hypertension and a hypertension exercise-test. After 2-5 years 55.9 per cent of all children with elevated blood pressure of the beginning of our study became normotensive without drug-therapy.

Adolescent↗

[Ergometric exercise tests in the diagnosis of juvenile hypertension].

We analysed 186 exercise stress-tests in children and adolescents with juvenile hypertension. 40 per cent of our patients showed an exaggerated rise of blood pressure during ergometric testing. There were no severe complications during exercise-tests. We recommended an antihypertensive drug therapy in cases of hypertensive resting blood pressure and hypertensive exercise-test. The ergometric investigation can control the effectiveness of drug therapy. Our data documented that 53.5 per cent showed a spontaneous remission of their elevated blood pressure after 3-5 years. There was no statistical dependence on the exaggerated rise of blood pressure during dynamic exercise-test.

Adolescent↗

[Histological findings of the small intestinal mucosa in rotavirus infections in infants and young children].

In a prospective study we performed small intestinal mucosal biopsies in 40 children with acute rotavirus diarrhoea. Biopsies were taken from these children between the 2nd to 10th day of acute phase. The children were at an age of less than 18 month. 95% of the patients had normal histological findings of the small intestinal mucosa. Only 2 children (5%) had well defined injuries of intestinal mucosa. Correlations were not found between clinical findings, morphological results and therapy. In one child with gastroenteritis and meningitis rotaviruses were found in cerebrospinal fluid. In 31.25% of all children rotavirus infection was acquired by a nosocomial infection. The treatment of rotavirus infection is symptomatic. Usually intestinal mucosal biopsy as a routine diagnostic method isn't recommended and it should be used only in intractable courses.

Biopsy↗

[A staged plan for laboratory diagnosis of hereditary metabolic diseases].

When clinical evidence provides grounds for suspecting inborn errors of metabolism it is urgent to perform the necessary, relevant, specific laboratory investigations in good time and with a view to quality. Normally, the realization depends on individual initiatives and the use of laboratories mainly designed for pediatrics and human genetics. Consequently the results are equally a matter of chance. Nothing in this situation can be changed in principle by using the catalogue of services of the Society for Human Genetics of the GDR. Central administrative provisions are necessary to improve the present unsatisfactory situation. Proposals for regulations, division of responsibility and a graduated programme of parameters are discussed here with a view to establishing uniform procedures.

Child↗

[Actual food intake of small children at a child day care center].

Investigations on the real food intake of children in day-care centres in the G.D.R. have not yet been carried out. Former studies compared the food intake with the recommendations for the daily intake of energy and nutrients. We have studied the daily food intake of 80 children in a day-care centre over a period of three weeks using the "simplified weighing method". The food intake at home was studied additionally by using a protocol method. The intake of energy during the stay in the day-care centre (three meals) amounted to 90 percent of the recommended quantity. The proportion of carbohydrates was lower and that of fat higher than the recommendations. The intake of iron and vitamin C was below the recommended doses. The total caloric intake and intake of fat per day were above the recommended values. Improvement of the composition of meals will help to overcome the disproportions observed.

Child Day Care Centers↗