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N Barbu

Publications and source records attributed to N Barbu.

At least 19 recordsLinked to original sources

Bacterial immunofluorescence in the intestinal juice of patients with nonspecific chronic enteropathy.

The bacterial immunofluorescence (BIF) in the intestinal juice was studied by the method of Virginia Thomas in a group of 26 patients with nonspecific chronic enteropathy (NCE). Our investigation revealed BIF in jejunal juice in 16 of 26 patients with NCE. The BIF test may be useful for the estimation of immune response to pathogenic germs at the level of the intestine.

Bacteria↗

Urinary infection in patients with chronic renal failure on hemodialysis.

A group of 37 hemodialyzed patients with chronic renal failure were investigated within a period of 6 months to 9 years. Of these patients five presented quantitatively significant bacteriuria noncorrelated with the causal nephropathy. Of the 9 patients with urologic past history two presented urinary infection. Urinary bacterial immunofluorescence was constantly positive in all the cases in which bacteriuria was significant and, at least in one determination when the germ count was below 10,000/ml. This finding was also supported by the increase of gammaglobulinemia and of the circulating immune complexes in all the cases investigated as well as of the B lymphocytes in one third of cases. Fifty percent of the patients presented T lymphocytopenia with excess of suppressor lymphocytes and deficit of the helper ones. It can, therefore be assumed that in patients with chronic renal failure nondialyzable antigens persist in the renal parenchyma where they stimulate anticorpogenesis but at a low level owing to some immune disturbances present in such patients.

Adult↗

The effect of the association of calcium channel inhibitors with antagonists of H2 histamine receptors on the gastric secretion in duodenal ulcer patients.

The effect of the association of verapamil (isoptin), a calcium channel inhibitor, with a cimetidine-like inhibitor of histamine receptors, on stimulated basal gastric secretion was studied in a group of 8 patients with duodenal ulcer. It was observed that by associating verapamil the effect of cimetidine was enhanced in most of the patients. The association of cimetidine with verapamil or other calcium channel inhibitors should be used especially in coronary patients with concomitant duodenal ulcer.

Cimetidine↗