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Biomedical subjects

N Ben Aderet

Publications and source records attributed to N Ben Aderet.

14 recordsLinked to original sources

Prenatal diagnosis of the pterygium syndrome.

We report two second trimester pregnancy terminations in the same woman following intrauterine ultrasonic findings of hydrops fetalis, polyhydramnios, lack of fetal movements, and short, fixed malformed limbs. One fetus also showed a cystic mass at the back of the head. Radiographic and anatomic studies of the fetuses demonstrated multiple pterygia, flexion contracture of multiple joints, abnormal facial appearance, cleft palate, pulmonary hypoplasia, and gracile bones. The cystic mass of the back of the head was found to be a cystic hygroma. These findings are consistent with the lethal variant of multiple pterygium syndrome. Early prenatal diagnosis of this condition is possible using ultrasonography.

Adult↗

Fetal death in early pregnancy due to electric current.

Electric shock injuries in pregnant women are rare events. The uterus and amniotic fluid are thought to be excellent conductors of electric current which reaches the fetus causing cardiac arrest and fetal death. All cases except one reported in the literature occurred in the third trimester, and ended with the death of the fetus. We report a case of a woman struck by a high voltage electric current in the 13th week of her pregnancy, causing fetal death and abortion.

Abortion, Spontaneous↗

Ultrasonic real-time diagnosis of transitory fetal pleural and pericardial effusion.

Congenital fetal effusions are rare and often fatal. Prenatal ultrasonic diagnosis is an important factor in both diagnosis and management of this condition. We report a case with both pleural and pericardial effusion, the ultrasonic diagnosis and follow-up, and the birth of a healthy baby. A short review of the literature is given.

Adult↗

Endocervical stromal sarcoma--a case report.

A case of a stromal sarcoma in a cervical polyp is presented. The tumor was confined to the polyp as evidenced by the histological examination of the uterus and cervix after surgery. In spite of that the patient died of widespread abdominal metastasis 1 year after the initial diagnosis.

Female↗

Urinary kallikrein in normal pregnancy, pregnancy with hypertension, and toxemia.

The 24-hour urinary excretion of kallikrein (K) and prostaglandin E2 (PGE2), which reflects their intrarenal synthesis, was measured in 7 normal women (NW), 10 women with essential hypertension (EH), 26 normal pregnant women (NP), 12 women with hypertension in pregnancy (HP), and 4 women with toxemia. All pregnant women were in the last trimester of their pregnancy (week 24-40). K was raised in NP (99.6 +/- 8.1 KU/24 h) and HP (106.5 +/- 8 KU/24 h) compared to NW (57 +/- 8.23 KU/24 h) (p less than 0.05). PGE2 excretion was decreased in EH (403.25 +/- 90.6 ng/24 h) compared to NW (508.6 +/- 80.26 ng/24 h). During pregnancy PGE2 was increased to 1,088 +/- 93.2 ng/24 h in NP and significantly more in HP, 1,885 +/- 40 ng/24 h (p less than 0.002). In this regard it differed from K. These data may suggest that, in addition to K, other factors (as angiotensin II and/or antidiuretic hormone) possibly activate renal PGE2 production in HP. In toxemia, K (23 +/- 6.1 KU/24 h) and PGE2 (583 +/- 172.83 ng/24 h) were markedly decreased. The above results suggest that the renal kallikrein-kinin and prostaglandin systems may play a role in sodium homeostasis during pregnancy. Their exact influence on the pathogenesis of hypertension in nonpregnant, pregnant, and toxemic subjects awaits further investigation.

Adolescent↗

Neonatal outcome of infants delivered at 26-28 weeks of gestation.

The delivery results of 42 infants born to 40 mothers at the gestational age of 26-28 weeks during a period of 5 years were analyzed. The study was evaluated in two periods of time: in the first period out of 15 infants born only 5 (33.3%) survived, while in the second period 21 (77.7%) out of 27 infants survived (p less than 0.01). 38 infants were transferred to a neonatal intensive care unit for premature infants. Only 41% of the infants transferred in the first period survived, as compared to 80.7% of those transferred during the second period (p less than 0.01). There was no significant difference in the mean birth weight at each gestational age between the survivors and those who subsequently died in both periods of the study. In the study groups, cesarean section rate rose from 13.3% in the first period to 44% in the second. Mode of delivery, regardless of the presenting part, did not seem to influence neonatal survival. Obstetrical management, including the performance of operative delivery for fetal indications and active neonatal resuscitation, seems to be reasonable for infants at the gestational age of 26 weeks or more.

Cesarean Section↗

Papillary adenofibroma of the endometrium: case report and review of the literature.

A case of papillary adenofibroma of the endometrium is reported in a 78-year-old parous woman. Diagnosis was made by curettage. The patient was treated by total abdominal hysterectomy with bilateral salpingo-oophorectomy. This is the eighth case known in the literature. Clinical and pathological aspects of this relatively new pathological entity are reviewed.

Adenofibroma↗

Ultrasonic screening in predicting the time of ovulation.

A consistent sign of imminent ovulation in the graafian follicle has been observed by ultrasonic screening. The sign is the appearance of a double contour along the follicle wall, with the wall losing its clear appearance. This is an important sign which can be used in all programs in which the exact timing of ovulation is important, in order to receive the best possible results in treatment of infertility.

Female↗

Perioperative mezlocillin prophylaxis in cesarean section.

One hundred thirteen patients were prospectively evaluated to determine the prophylactic effect of mezlocillin in women undergoing cesarean section. Subjects received 2 gm of mezlocillin or placebo intravenously 30 minutes before surgery and four and nine hours after surgery. All patients were evaluated for febrile morbidity and for the development of specific infections. The overall postoperative morbidity was reduced from 51% in the control group to 17% in the mezlocillin group (P less than 0.01). Separate analyses of morbidity in patients undergoing cesarean section after the onset of labor and those having the operation before the onset of labor showed the significant reduction of morbidity by mezlocillin to have occurred only in the former group.

Adult↗