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Biomedical subjects

N Bhandare

Publications and source records attributed to N Bhandare.

3 recordsLinked to original sources

Computer-CT planning of the electron boost in definitive breast irradiation.

Treatment planning of the electron boost in breast irradiation at this institution is performed by using information from CT scanning and from surgical clips used to define the tumor bed. A refinement of this technique, taking into account the surgical axis of approach, using computer-CT planning is now implemented. The location of the scar and the clips are digitized using a computer to define the tumor bed dimensions. With 3-D computer software a line, simulating the surgical axis and the central ray of the electron beam, is drawn between the deepest clip and the surgical scar. This beam's eye view along the surgical axis is projected onto a screen as a starting point. Appropriate gantry angle, treatment table position, beam energy, and precise shaping of the electron field borders with a 2 cm margin around the clips and the scar are determined. Simulation films comparing clinically set-up fields and computer-CT planned fields were reviewed. In only 5 of 17 patients did the clinically set-up field have adequate inclusion of the tumor bed within the treatment volume. Computer-CT planned fields ensured adequate inclusion of the tumor bed in all, including the remaining 12. In 7 patients obvious increased sparing of normal breast tissue was seen with computer-CT planned fields. This technique enables accurate placement of a shaped electron field and further refinement of electron boost treatment planning. This is especially true in situations in which the tumor bed is located at a site distant from the lumpectomy scar rather than directly beneath it and in cases where the tumor bed lies deep within the breast.

Breast Neoplasms↗

A new design of Delclos dome cylinders using standard Cs-137 sources.

Surface dose rates around the currently-marketed Delclos uterine-vaginal afterloading dome (hemispherical) cylinders were calculated and measured for linear standard 3M cesium tube sources. Measurements were carried out using thin thermoluminescent lithium fluoride Chips on the surface of the cylinder and calculations at the same points were generated using a treatment planning computer. Wide surface dose variations were found for 2 to 3.5 cm diameter cylinders, but relatively small variation for 4 to 4.5 cm diameter cylinders. Attempting to achieve a uniform dose distribution around the entire dome surface of the cylinder, we have developed a new ellipsoidal design for the dome component that better conforms to the shape of the isodoses arising from the distal-most source. Thermoluminescent dosimetry indicates that the surface doses for the newly constructed cylinders are quite uniform, with variation within +/- 5%. The effect on surface dose is discussed when the ellipsoidal dome cylinder in combination with vaginal cylinders is used and multiple sources are laid end to end to treat the added areas of the vaginal wall.

Brachytherapy↗