Biomedical subjects
Publications and source records attributed to N Bundgaard.
Two cases of tuberculosis in the parotid gland are presented. In both cases, the patients were submitted to operation on account of a suspected parotid tumour. Histological examination, revealed, surprisingly, tuberculosis. This is a rare form of extrapulmonary tuberculosis and only four cases were referred to the Tuberculosis Register in Denmark in 1988.
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Mediastinoscopy was performed in 470 patients with bronchogenic carcinoma in the ENT Department, Aalborg. The histological diagnoses were 195 squamous cell carcinomas, 149 adenocarcinomas, and 126 anaplastic carcinomas. Metastases in the mediastinal lymph nodes were found in 177 of the 470 patients (38%). Metastatic lymph nodes were found in approximately one fifth of the squamous cell carcinomas, in almost half of the adenocarcinomas, and in about half of the anaplastic carcinomas. The need is emphasized for lymph node biopsy from both right and left tracheobronchial angles and inferior to the bifurcation irrespective of the site of the carcinoma. Contralateral metastasis was found in approximately one third of the cases, and a positive biopsy from the nodes inferior to the bifurcation was found in about 40% of the patients in whom metastasis in the mediastinum were detected. In 10% of the patients, cytological and histological examinations of specimens obtained by bronchoscopy were negative, and the diagnosis of lung cancer was made by mediastinoscopy exclusively. The value of mediastinoscopy was particularly high in the diagnosis of adenocarcinomas.
Blood in sputum, haemoptysis, is a common symptom in mucous membrane disorders of the respiratory tract--it is often seen in conjunction with inflammation but may also be associated with malignant tumours of the respiratory tract. In a survey of 422 patients with monosymptomatic haemoptysis, 15 patients with bronchogenic carcinoma were identified. A cytological examination of the sputum of these 15 patients was carried out, and in 9 of these cases suspected malignant cells were observed. From these and other observations it is concluded that with patients of over 40 years of age who are smokers with haemoptysis, but who display a normal X-ray examination of the thorax, it would be prudent to carry out a cytological examination of the sputum before bronchoscopy.
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Twelve cases of adenolymphoma with inflammation are described. Pre-operatively, three of these patients presented clinical signs of inflammation in the parotid gland. In ten cases purulent exudate could be aspirated from the tumour. Rupture of the cyst may cause an aseptic inflammation in the surrounding tissue. It is concluded that adult patients with clinical or cytological signs of inflammation in the parotid gland must be supervised until the gland is normal in order not to miss an underlying tumour.
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Cystadenomas of the seminal vesicle are extremely rare benign tumours, which only have been reported seven times earlier in the literature. The first Danish case is reported with discussion of symptomatology, pathology and treatment.
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