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Biomedical subjects

N C DELARUE

Publications and source records attributed to N C DELARUE.

At least 19 recordsLinked to original sources
PubMed1965

THE SURGICAL TREATMENT OF PULMONARY EMPHYSEMA.

Emphysema may be focal or multifocal. In either type an area of disease may enlarge and reduce the function of adjacent lung.Thirty patients who required treatment for emphysema and its complications are described. Fifteen patients with focal emphysema that did not constitute a space-occupying lesion required operation because of recurrent pneumothorax or infection in the affected area. The results were excellent. Ten patients with focal emphysema and progressive "space occupation" complained of moderate but increasing dyspnea. Removal of the enlarging lesion resulted in marked improvement. Five patients with multifocal emphysema and progressive space occupation in one focal area suffered from severe dyspnea and poor general health. The space-occupying lesion was removed by lobectomy. The results, measured by pulmonary function tests and subjective improvement, were rewarding in most cases. No patient with multifocal emphysema but without a space-occupying lesion under-went operation.

Classification↗
PubMed1964

OPEN LUNG BIOPSY.

Steady improvement in the diagnostic appraisal of obscure pulmonary and mediastinal disease has permitted more intelligent treatment, better prognosis, and where necessary more accurate assessment of compensability. Open lung biopsy is designed to obtain material for pathological study when there is no pleural, mediastinal, or airway lesion on which to base a working diagnosis.A study of 54 patients in whom lung biopsy was performed at the Toronto General Hospital and Weston Sanatorium is reported. A positive tissue diagnosis was obtained in approximately 75%. The procedure is considered relatively innocuous if sensible selection is exercised to exclude patients with terminal disease, particularly that associated with severe cardiorespiratory insufficiency. No major complications occurred in this series. It is concluded that open lung biopsy might reasonably receive much wider application than in the past in cases in which a definite diagnosis cannot otherwise be made.

Adenocarcinoma, Bronchiolo-Alveolar↗