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Biomedical subjects

N C De

Publications and source records attributed to N C De.

At least 19 recordsLinked to original sources
PubMed1995

A new nematode, Dichelyne alatae sp. n. (Cucullanidae), from Sillaginopsis panijus (Pisces) of West Bengal, India.

A new nemarode, Dichelyne alatae sp. n., is described on the basis of the worms recovered from the intestine of the whiting, Sillaginopsis panijus (Perciformes: Sillaginidae) from the estuary of the river Hooghly at Kalyani, West Bengal, India. Dichelyne alatae differs from congeners in having a small body size, deirids posterior to the oesophagus, short and wide caudal alae at the level of cloacal opening, unequal, alate spicules, a shield-shaped gubernaculum, a different number of caudal papillae and a conical tail with spines in its distal region.

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PubMed1993

Seasonal dynamics of Camallanus anabantis infections in the climbing perch, Anabas testudineus, from the freshwater swamps near Kalyani town, West Bengal, India.

The seasonal changes of the nematode Camallanus anabantis Pearse, 1933, in the climbing perch (Anabas testudineus) from the freshwater swamps near Kalyani town, West Bengal, India were studied during the period from February 1988 to August 1989. The nematode exhibited a one-year cycle. Larvated females occurred in the fishes from October to February at a water temperature of 12 degrees-29 degrees C. New infection of fishes occurred from February to May and occasionally in September. The fourth-stage larvae, the males, and the young females (without eggs), although irregularly, were found present throughout the year. Egg-laden females occurred in the fishes in August, October to February, and March.

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PubMed1992

A scanning electron microscope study of Raillietascaris varani (Baylis et Daubney, 1922) (Nematoda: Ascaridioidea).

The Raillietascaris varani (Baylis et Daubney, 1922), parasitic in the Indian monitor lizard, Varanus monitor (L.), was studied by scanning electron microscopy (SEM). A surface topography of the worm, especially the head and male tail, were described, illustrated and discussed with regard to the available data on this species, and also other species of ascaridoid nematodes. The present study confirms the previous observations from Sprent (1985), and also provides some additional information concerning the microtopography of the worm which might be useful in comparative studies on the Ascaridoidea.

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PubMed1990

Some new data on the morphology of the nematode Lappetascaris lutjani Rasheed, 1965 (Nematoda: Anisakidae).

The nematode, Lappetascaris lutjani, recovered from the fish, Pellona ditchela from West Bengal, India, was studied by light and scanning electron microscopes. Surface features of the head and tail ends of the body as also the distal parts of the spicules were described, illustrated and discussed with regard to the available data relative to this species. Present LM studies provide information concerning the head structure in greater detail and existence of narrow but distinct lateral cervical alae. SEM studies give microtopographic details of the worm. Some of these represent new information and might be useful in the taxonomic evaluation of this interesting nematode. P. ditchela is the recorded new host of L. lutjani.

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PubMed1988

Data on the morphology of the nematode Spinitectus minor (Stewart, 1914) (Nematoda: Cystidicolidae).

Morphology of the nematode Spinitectus minor harboured by Mastacembelus armatus from Burdwan, West Bengal, India was studied by light and scanning electron microscopes. The worms were described, illustrated and discussed taking into consideration of the information available relative to this species. Alate spicules, polar caps on the eggs and prodelphic uteri are clearly seen in the present LM studies and SEM photomicrographs provided detailed information about the microtopography of the worms.

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PubMed1986

Stability of pentamidine isethionate in 5% dextrose and 0.9% sodium chloride injections.

The stability of pentamidine isethionate in small-volume intravenous admixtures was studied. In an initial experiment, duplicate admixtures containing pentamidine 1 or 2 mg/mL were prepared using 100 mL each of 5% dextrose injection and 0.9% sodium chloride injection in polyvinyl chloride (PVC) bags. All solutions were kept at room temperature and were assayed at various times up to 48 hours by high-performance liquid chromatography. Solutions were also examined visually and tested for pH at each assay time. In a second experiment, single admixtures containing pentamidine 2 mg/mL were prepared in 100-mL PVC bags of both 5% dextrose injection and 0.9% sodium chloride injection. After time-zero determinations of pentamidine concentration, pH, and visual clarity, solutions were allowed to run through PVC infusion sets at 20 mL/hr. Samples were collected at the distal end of each set at various times up to five hours for analysis of pentamidine concentration, pH, and clarity. All admixtures in the initial experiment retained greater than 90% of initial concentration for the 48-hour study period. However, 5% dextrose admixtures infused through PVC administration sets showed a loss in initial concentration of about 2%, while 0.9% sodium chloride admixtures lost about 10% of initial concentration after infusion through these sets. The pH of all solutions in both experiments varied by less than 0.5 units, and no particulate matter or color change was noted in any of the admixtures. In the concentrations and diluents studied, pentamidine appears to be stable for 48 hours in PVC bags. Slight losses in the initial concentrations of these solutions after infusing them through PVC infusion sets may be caused by adsorption to the set.

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PubMed1984

Redescription of Neocamallanus singhi (Nematoda: Camallanidae) with a note on related species.

The present paper deals with the redescription of the nematode Neocamallanus singhi Ali, 1957 based on specimens collected from the fish, Channa striata from Burdwan, West Bengal, India. Comparative study of this species with other related forms described from freshwater fishes of India and Pakistan indicates that Neocamallanus bengalensis Soota et Chaturvedi, 1971 and N. ophicephali Rehana et Bilquees, 1972 are synonyms of N. singhi.

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PubMed1976

Synthesis and biological activities of some N4-substituted 4-aminopyrazolo(3,4-d)pyrimidines.

Syntheses and biological activities of 26 N4-substituted 4-aminopyrazolo[3,4-d]pyrimidines as analogs of naturally occurring modified nucleic acid bases, N-(purin-6-ylcarbamoyl)-L-threonine and N6-(delta2-isopentenyl)adenine, are described. 4-Aminopyrazolo[3,4-d]pyrimidine was converted into the desired intermediate, ethyl pyrazolo[3,4-d]pyrimidine-4-carbamate (2). 4-Ureidopyrazolo[3,4-d]pyrimidines (6-26) were prepared by displacement of the ethoxy group of the carbamate 2 by amino acids and a variety of amines and by a reaction of 4-aminopyrazolo[3,4-d]pyrimidine (1) with isocyanates. N4-Alkylaminopyrazolo[3,4-d]pyrimidines were generally prepared by displacement of the chlorine from 4-chloropyrazolo[3,4-d]pyrimidine with various amines. Several analogs exhibited moderate to very good growth inhibitory activities against cultured L1210 leukemia and 6410 human leukemic myeloblasts.

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