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Biomedical subjects

N C Elliott

Publications and source records attributed to N C Elliott.

9 recordsLinked to original sources
PubMed2004

Biological control of cereal aphids in north america and mediating effects of host plant and habitat manipulations.

The predator and parasitoid fauna associated with cereal aphids is described, emphasizing the fauna associated with classical biological control efforts against the greenbug and Russian wheat aphid. We focus on literature from North America and include work from Europe and elsewhere when it is desirable to draw contrasts between approaches that affect cereal aphid biological control. Effects on natural enemies of cereal aphids are described that appear associated with plant traits that are innate, bred, or induced by aphid feeding. Examples of habitat manipulations, within and bordering cereal fields and within the broader landscape in which cereal production resides, affecting predators and parasitoids of cereal aphids are presented. These mediating effects of host plant and habitat manipulations on cereal aphid biological control provide significant and underexplored avenues to optimize cereal aphid management.

Animals↗
PubMed2003

Fixed precision sequential sampling plans for the greenbug and bird cherry-oat aphid (Homoptera: Aphididae) in winter wheat.

The numbers of greenbugs, Schizaphis graminum (Rondani), and bird cherry-oat aphids, Rhopalosiphum padi L., per wheat tiller (stem) were estimated in 189 production winter wheat (Triticum aestivum L.) fields located throughout Oklahoma. Taylor's power law regressions were calculated from these data and used to construct fixed precision sequential sampling schemes for each species. An evaluation data set was constructed from 240 samples taken during three growing seasons from winter wheat fields at four locations in Oklahoma. Wheat cultivar and growth stage were recorded for each field on the day of sampling. Taylor's power law parameters for evaluation fields differed significantly for both species among growing seasons, locations, and plant growth stages. Median precision achieved using the fixed precision sequential sampling schemes for each species departed <20% from expected precision over the range population intensity in the evaluation data. For the 10% of samples with greatest deviation between observed and expected precision, observed precision was 13.8-81.8% greater than that expected precision depending on aphid species and population intensity. For the greenbug, the distribution of the percentage deviation between observed and expected precision was positively skewed, so that the sampling scheme tended to over-predict precision. For the bird cherry-oat aphid, the distribution was more symmetric. Even though precision observed using the sampling schemes frequently varied from expected precision, because of the inevitable consequence of sampling error and environmental variation, the sampling schemes yielded median observed precision levels close to expected precision levels over a broad range of population intensity.

Agriculture↗
PubMed2002

Effect of greenbugs (Homoptera: Aphididae) on yield loss of winter wheat.

The effect of greenbug, Schizaphis graminum (Rondani), feeding on the yield of four winter wheat cultivars commonly grown in Oklahoma was studied. Cultivars tested were 'Karl', a recent derivative 'Karl-92', and '2163', all greenbug-susceptible cultivars; and 'TAM-110', a cultivar with resistance to biotype E greenbugs. The objectives were to determine the effect of different greenbug densities during fall and spring on yield of winter wheat, and to develop mathematical models to quantify the effect of greenbugs on yield loss. The intensity of greenbug infestations achieved in plots by artificial infestation varied among years and growing seasons within a year, but was generally sufficient to cause a reduction in yield. Among yield components, the number of heads per square meter and the number of seeds per head were frequently negatively correlated with the accumulated number of greenbug-days per tiller. Seed weight was rarely affected by greenbug infestation. A regression model estimated yield loss for greenbug-susceptible cultivars at 0.51 kg/ha loss of yield per greenbug-day in years with near normal precipitation, and a loss of 1.17 kg/ha under severe drought conditions. The susceptible winter wheat cultivars exhibited similar yield loss in relation to the intensity of greenbug infestation, as indicated by a common slope parameter in the regression model. Results suggest that the model is robust for predicting yield loss for susceptible cultivars.

Animals↗
PubMed2000

Development and validation of a binomial sequential sampling plan for the greenbug (Homoptera: Aphididae) infesting winter wheat in the southern plains.

From 1997 to 1999, Schizaphis graminum (Rondani), intensity (number per tiller) was estimated on 115 occasions from hard red winter wheat fields located throughout the major wheat growing regions of Oklahoma. A total of 32 and 83 fields was sampled during the fall and spring, respectively. The parameters of linear regressions relating the mean number of greenbugs per tiller (m) and the proportion of infested tillers (PT) differed significantly between fall and spring infestations. The PT-m linear model provided a good fit for data on S. graminum for fall and spring infestations at tally thresholds of 0, 1, 2, and 3. A tally threshold (T) represents the number of greenbugs present on a tiller before the tiller is classified as infested by >T greenbugs. A regression model with a tally threshold of 2 was the most precise for classifying S. graminum populations during fall growth of winter wheat because it explained a greater amount of the variation in the PT-m relationship (97%) than models with other tally thresholds. A separate spring model with a tally threshold of 1 was the most precise for classifying S. graminum populations during spring growth of winter wheat. Sequential sampling stop lines based on sequential probability ratio tests were calculated for economic thresholds of 3 or 6 greenbugs per tiller for fall infestations and 6 or 9 greenbugs per tiller for spring infestations. With the newly developed parameters, the average sample number required to classify greenbug populations near economic thresholds (as above or below the economic threshold) varied from 69 to 207. We expect that the sampling plans for greenbugs in winter wheat developed during this study will be efficient and useful tools for consultants and producers in the southern plains.

Animals↗
PubMed1992

Synthesis and structure-activity relationships of 7-diazabicycloalkylquinolones, including danofloxacin, a new quinolone antibacterial agent for veterinary medicine.

A series of novel 6-fluoro-7-diazabicycloalkylquinolonecarboxylic acids substituted with various C8 (H, F, Cl, N) and N1 (ethyl, cyclopropyl, vinyl, 2-fluoroethyl, 4-fluorophenyl, 2,4-difluorophenyl) substituents, as well as, 9-fluoro-10-diazabicycloalkylpyridobenzoxazinecarboxylic acids, were prepared and evaluated for antibacterial activity against a range of important veterinary pathogenic bacteria. The diazabicycloalkyl side chains investigated at the 7-position (benzoxazine 10-position) include (1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptane (2), (1S,4S)-2,5-diazabicyclo[2.2.1]heptane (3), (1R,4R)-5-methyl-2,5-diazabicyclo[2.2.1]heptane (4), 8-methyl-3,8-diazabicyclo[3.2.1]octane (5), 9-methyl-3,9-diazabicyclo[4.2.1]nonane (6), 1,4-diazabicyclo[3.2.2]nonane (7), 1,4-diazabicyclo[3.3.1]nonane (8), and 9-methyl-3,9-diazabicyclo[3.3.1]nonane (9). Among these side chains, in vitro potency was not highly variable; other properties therefore proved more critical to the selection of possible development candidates. However, the relative potencies observed for several of these compounds in mouse, swine, and cattle infection models correlated well with those seen in vitro. A combination of the N1 cyclopropyl group and the C7 (1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl appendage conferred the best overall antibacterial, physiochemical, and pharmacodynamic properties. Hence, danofloxacin (Advocin, 2c) (originally CP-76,136, 1-cyclopropyl-6-fluoro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1] hept-2-yl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid) was selected as a candidate for development as a therapeutic antibacterial agent for veterinary medicine.

Actinobacillus Infections↗
PubMed1979

Accumulation of 125I in the oocytes, thyroids, and plasma of laying Japanese quail treated with cyclic AMP, theophylline, or prostaglandins E1 or E2.

Dibutyryl cyclic AMP, theophyline, or prostaglandins E1 or E2 were injected intraperitoneally into laying Japanese quail in an attempt to stimulate increased transference of iodide by the ovarian membranes. Theophyline induced increased 18-hr 125I accumulations (by 7 to 18% of the injected dose) of borderline significance in the growing oocytes of some test groups. Theophyline plus DBcAMP treatment lead to a slight increase in 125I accumulation in the thyroid. Other treatments had no apparent effect on 125I transference. The prostaglandins induced oviposition within minutes of injection, as has been reported for uterine application of prostaglandins by other investigators. Means for plasma 125I levels for treated quail were 1.7 to 12.5 times greater than control levels. Values for oocyte to plasma and thyroid to plasma 125I ratios, it appeared that DBcAMP, theophyline, and the prostaglandins inhibited rather than stimulated the accumulation of 125I by the ovary and thyroid of the quail.

Animals↗
PubMed1977

Accidental suppression of the accumulation of radioiodide by the thyroids of Japanese quail exposed to an iodinated disinfectant.

The walls and floor of a room housing a Japanese quail colony were treated with a commercial disinfectant containing iodine complexed to organic molecules. The room was washed vigorously with hot water using a pressure hose, a procedure discouraged by instructions on the shipping container. A condensate, tinged yellow-brown presumably by elemental iodine, settled on the walls, ceiling and quail pens. Accumulations of tracer doses of iodide-125 or iodide-131 by the thyroid glands of these birds were approximately one-seventh (6-hour uptake) to one-thirtieth (18-hour uptake) as great as for control birds from non-disinfected areas.

Animals↗