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Biomedical subjects

N C Johnson

Publications and source records attributed to N C Johnson.

4 recordsLinked to original sources

Outcomes of cleft care in Western Australia: a pilot study.

The purpose of this study was to compare outcomes and delivery of cleft care in Western Australia with the average standard of care in the United Kingdom (UK). This was achieved through a cross-sectional study involving children born with unilateral cleft lip and palate between April 1983 and March 1985 (12 year olds) or between April 1990 and March 1992 (5 year olds). A total of 38 children born with unilateral cleft lip and palate were under the care of the cleft team based at Perth's Princess Margaret Hospital. Dental arch relations, facial skeletal pattern, speech, hearing, success of alveolar bone grafting and dental health were measured. It was found that fewer Princess Margaret Hospital children in both age cohorts had revision surgery and speech therapy compared with the UK average. The facial skeletal pattern, speech, hearing and alveolar bone grafting outcomes from Princess Margaret Hospital were similar to the UK at age 12. Seventeen per cent of the Princess Margaret Hospital 12 year olds had a poor dental arch relationship compared with 39 per cent in the UK. In the 5 year olds, most outcomes in Princess Margaret Hospital patients appeared better than the UK with lower residual treatment needs. While it is difficult to draw firm conclusions because of the small numbers involved, this study indicates standards need to be set and determined for Australia.

Bone Transplantation↗

Tooth position and speech--is there a relationship?

Although it is widely accepted that teeth play an important role in speech production, the relationship between tooth position and speech remains controversial. This review paper examines the relevant studies and discusses the difficulties of scientific investigation in this area. The ability of patients to adapt their speech to compensate for abnormal tooth position is recognized, but the mechanisms for this adaptation remain incompletely understood. The overall conclusion is that while certain dental irregularities show a relationship with speech disorders, this does not appear to correlate with the severity of the malocclusion. There is no definitive proof that alteration of tooth position can improve articulation disorders.

Adaptation, Physiological↗

The effect of a diuretic (hydrochlorothiazide) on tear production in humans.

The effect of an orally administered diuretic, hydrochlorothiazide, on tear production in 11 normal young human subjects (five men and six women, 18 to 35 years old) was measured in a single-masked study. Schirmer tests with topical anesthetic showed a significant (P = .02) decrease in basal aqueous tear production on days when these subjects were taking the diuretic. The average decrease was 2.1 mm of wetting in five minutes.

Adolescent↗