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Biomedical subjects

N Chater

Publications and source records attributed to N Chater.

At least 19 recordsLinked to original sources

Arterial anastomoses and autogenous interposition grafts in growing rats.

The fate of arterial interposition grafts in growing rats was investigated. The interrupted- and continuous-suture techniques were compared to see which allowed for better expansion of the anastomosis. We found that a graft enlarges in proportion to the growth of the parent vessel, that in end-to-end anastomosis the interrupted suture technique allowed for better expansion of the anastomosis (but not in the end-to-side model), and that the continuous suture technique was associated with a higher rate of false aneurysm formation.

Aneurysm

Neurosurgical extracranial-intracranial bypass for stroke: with 400 cases.

An update of the current status of neurosurgical microvascular bypass for problems of cerebrovascular occlusive disease is presented. In 400 patients who have undergone operations by one surgeon, the results are encouraging in cases of transient ischemic attacks with hemodynamic lesions previously considered inoperable or inaccessible in the cerebral vasculature. The permanent neurological morbidity rate is 2% and the present operative mortality rate is 2.5%. The incidence of stroke to date on the side of a functioning bypass is 0.9% per year. Average follow-up is 55 months.

Cerebral Revascularization

Results of neurosurgical microvascular extracranial-intracranial bypass for stroke: a decade of experience.

In 400 patients who have had neurosurgical microvascular bypass operations by one surgeon for problems of cerebrovascular occlusion disease, the results are encouraging, particularly in those who had transient ischemic attacks with hemodynamic lesions previously considered inoperable or inaccessible. The permanent neurologic morbidity rate is 2 percent and the present operative mortality is 2.5 percent. The incidence of stroke to date on the side of a functioning bypass is 0.9 percent per year. Average duration of follow-up is 43 months.

Aged

Extracranial to intracranial vascular anastomosis for occlusive cerebrovascular disease: experience in 110 patients.

In an attempt to ascertain the value of extra- to intracranial arterial bypass for cerebrovascular disease, the general topic of bypass surgery is reviewed and the results of this procedure in 110 patients are analyzed. The feasibility of high patency rates of the anastomosis with acceptably low permanent morbidity and operative mortality rates is demonstrated. Lesions producing transient ischemic attacks which previously were considered to be inoperable or inaccessible can be bypassed by this procedure, and there appears to be a dramatic improvement in the symptomotology of virtually all patients. Patients with a mild stroke or "progressive stroke" also appear to benefit from bypass, but the erratic natural history of these entities precludes irrefutable substantiation of this conclusion. Patients with moderate-to-serve neurological deficits do not appear to be improved by this procedure. In our group of 20 patients presenting with transient ischemic attacks who have had more than 3 years of follow-up, only one patient has suffered a stroke and that was located in the opposite hemisphere.

Adult

Microvascular bypass surgery. Part 1: anatomical studies.

Microvascular anatomical studies were performed to ascertain the most suitable cortical vessel for extracranial-intracranial arterial bypass (EIAB). The three most commonly used cortical areas (the tip of the frontal lobe, the tip of the temporal lobe, and the area at the angular gyrus) were examined in detail. Because of their accessiblity and size, the cortical arteries in the area of the angular gyrus offer the most suitable location for creating an EIAB.

Cerebral Arteries

Microvascular bypass surgery. Part 2: physiological studies.

Intraoperative electromagnetic blood flow measurements were recorded in 15 patients undergoing extracranial-intracranial arterial bypass surgery. The initial average blood flow of 28.2 cc/min supplies 8.4% of the expected flow from one internal carotid artery. Blood flow probably increases postoperatively, as evidenced by angiographic enlargement of the bypass and its recipient cortical arteries.

Adult

Neurosurgical microvascular bypass for stroke.

A review of the present status of neurosurgical vascular bypass for problems of cerebrovascular occlusive disease is presented. In 70 patients who have undergone operations by one surgical team, the results are most encouraging in cases of transient ischemic attacks with hemodynamic lesions previously considered inoperable or inaccessible in the cerebral vasculature. The morbidity rate is acceptable and the present operative mortality rate is 1.4 percent.

Aged

Microsurgical vascular bypass for occlusive cerebrovascular disease; review of 100 cases.

This is a report on a series of 100 consecutive patients who had undergone microvascular arterial bypass surgery as an aid in the treatment of occlusive ischemic cerebrovascular disease. The results to date are encouraging in cases of transient ischemic attacks (TIA) with significant hemodynamic vascular lesions previously considered inaccessible or inoperable by conventional vascular surgical techniques. The permanent morbidity rate is low. The operative mortality rate is acceptable. Postoperative patency rates of the surgical bypass remain high. In analyzing the cases presenting with TIA, the total incidence postoperatively to stroke is 6% in the series to date. The average postoperative follow-up is 20 months.

Adult