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Biomedical subjects

N Chraibi

Publications and source records attributed to N Chraibi.

At least 19 recordsLinked to original sources

[Cardiac hydatid cysts: report of 10 cases].

Authors report 10 observations of cardiac hydatid cyst collected to cardiovascular unit of Ibn Rochd hospital in Casablanca during last 7 years. Clinical investigation included in all cases chest X ray, ECG and ultrasonography (US). A computed tomography (CT) scan was performed in 6 cases, magnetic resonance imaging in four cases, transoesophageal US in two cases. Examination for other hydatic sites was realized in all cases, and brain CT was performed in 5 cases. The hydatid cyst was variably localized in the left ventricle in 6 cases, the pericardium in 4 cases, the interventricular septum in 2 cases, the right auricle in 2 cases and multiple locations in one case. The existence of other cardiac hydatid sites was found in 7 cases. Seven patients have been operated (2 cases to closed heart). Outcome was favorable in 6 cases with a mean of three years survey. Two patients died and 2 others have been lost of view. The diagnosis of the cardiac hydatid cyst has benefits from the combination USCT scan that allowed a precise topographical inventory, reducing the need for MRI to the complicated cases and to the rare cases of inconclusive results by US-CT scan.

Adolescent↗

[Right intracardiac thrombus in Behçet's disease].

The authors report the clinical history of a 22-year-old woman, followed for Behçet's disease, who presented a prolonged fever for two months associated with oral and genital ulcerations. There was an inflammatory syndrome, papillary oedema without brain injury. Echocardiography revealed moderate pericardial effusion and voluminous thrombosis of right atria and right ventricle. Chest computed tomography showed a lung infarction without thrombosis of pulmonary artery. The antiphospholipid antibodies were negatives. The treatment was based on corticotherapy and anticoagulation with a good outcome. In Behçet disease, cardiac involvement manifestations as pericardial, myocardial or endocardial lesions. This case underlines the rarity of cardiac thrombosis in Behçet disease.

Adrenal Cortex Hormones↗

[False aneurysm complicating ligation of patent ductus arteriosus operated on successfully].

Postoperative aneurysm of ductus arteriosus is a rare complication but may be lethal without treatment. It is less frequent than spontaneous aneurysm of ductus arteriosus. We report the case of 5 years-old girl who underwent a ligation of patent ductus arteriosus complicated, 6 months later, with a false aneurysm of ductus arteriosus and endocarditis of the ductus and the aortic valve. The diagnosis of the aneurysm was suspected on the anteroposterior chest X-ray which showed a left superior mediastinal opacity and confirmed by echocardiography. Through bilateral thoracotomy, an anevrismorraphy and aortic repair was carried out without problem. The postoperative course was unremarkable.

Aneurysm, False↗

[Cardiovascular abnormalities of the antiphospholipid antibody syndrome].

The antiphospholipid antibody syndrome (APS) may present with serious cardiovascular complications which should be recognised by the cardiologist. The authors report a series of 6 cases of APS diagnosed after thrombotic events and the finding of antiphospholipid antibodies. The APS was primary in 5 cases and associated with tuberculous lymphadenitis in 1 case. There was cardiac involvement in 5 patients with pericardial effusion in 3 cases, complicated by tamponade as the presenting sign of primary APS in the other 2, valvular disease in one case (moderate mitral stenosis with aortic valve disease) and pulmonary embolism in one case. Five patients developed recurrent deep vein thrombosis of the legs. One patient had a transient ischaemic cerebral attack.

Adult↗

[Hypertrophic cardiomyopathy disclosing Friedreich's disease. Report of a case].

The authors report the case of a 21 year old woman admitted to hospital for congestive cardiac failure due to concentric hypertrophic cardiomyopathy. Echocardiography showed severe systolo-diastolic left ventricular dysfunction without obstruction to ejection. Neurological examination showed a stato-kinetic cerebellar syndrome, a posterior radiculo-cordonal syndrome and a dysmorphic syndrome which characterise Friedreich's disease. In the light of this case and a review of the literature, the authors underline the rarity of cardiomyopathy in Friedreich's disease, its particular presentation and its poor prognostic significance in this disease.

Adult↗

[Study of variations in preload on the new echocardiography parameters of diastolic function in health subjects].

The standard Doppler indices of transmitral filling are changed by variations in preload, relaxation and left ventricular compliance. Recent work in the literature suggests that the new parameters of diastolic function [mitral flux propagation speed in colour TM. (Vp) and tissue Doppler mitral ring velocities (Ea)] are independent of loading conditions. The objective of this work was to study the effect of modifications in the preload on Vp and Ea in normal subjects. Therefore, we have studied various Doppler echocardiographic measurements performed at rest, during a Trendelenberg manoeuvre at 60 degrees, and after sublingual administration of trinitrate in 25 healthy young (2 +/- 8 years) male volunteers. The end diastolic volume increased from 126 +/- 25 ml in the resting state to 145 +/- 24 ml during the Trendelenberg (p = 0.009) then decreased after trinitrate to 121 +/- 28 ml. The peak of the E wave increased from 88 +/- 12 cm/s in the resting state to 90 +/- 15 cm/s during the Trendelenberg and decreased to 70 +/- 11 cm/s after trinitrate (p < 0.0001). The peak Ea annular velocities of the septal and lateral walls were 22 +/- 4 cm/s and 15 +/- 1.6 cm/s in the resting state, without variation during the Trendelenberg (22 +/- 5 cm/s and 15 +/- 2 cm/s) but with a significant reduction after trinitrate to 19 +/- 5 cm/s and 13 +/- 2 cm/s (p = 0.02 and p = 0.002). In contrast, no significant variation was noted in Vp (60 +/- 14 cm/s in the resting state, 62 +/- 12 cm/s during the Trendelenberg and 59 +/- 14 cm/s after trinitrate). We conclude that Vp is not significantly affected by preload whereas Ea is not independent of the loading conditions.

Adult↗

[Aneurysm of the posterior sinus of Valsalva ruptured into right atrium].

Sinus of Valsalva aneurysm is rare malformation, which takes origin from one of the three aortic sinuses. Diagnosis of this abnormality is usually made when rupture has occurred. Our observation underlines the severity of the posterior sinus of Valsalva aneurysm ruptured into right atrium, and emphasizes the utility of transthoracic and transoesophageal echocardiography for diagnosis.

Adult↗

[Obstructive left triatrial heart in the adult. Echocardiographic appearances].

The authors report the case of a 23-year old man who presented with signs of pulmonary hypertension due to an obstructive left triatrial heart in adulthood. Transthoracic and transoesophageal echocardiography showed a partially calcified intra-left atrial membrane perforated in its centre. Doppler analysis of flow through the membrane showed continuous systolo-diastolic flow at high velocity indicating haemodynamic obstruction. The systolic pulmonary artery pressure was estimated at 80 mmHg. The patient was treated by surgical excision of the intra-left atrial membrane.

Adult↗

[Malignant non-Hodgkin's lymphoma presenting with cardiac tamponade].

Malignant non-Hodgkin's lymphoma rarely involves the heart. However, all cardiac structures may be invaded, although the myocardium and pericardium are affected more often than the valvular structures. Diagnosis is important because treatment must be adapted. The cardiac signs are usually non-specific and lymphomas presenting in this way have only occasionally been reported. The authors report two cases in which malignant non-Hodgkin's lymphoma presented with cardiac tamponade.

Adult↗

[Hypocalcemic dilated cardiomyopathy: rare cause of heart failure].

Hypocalcemic dilated cardiomyopathy is a rare cause of heart failure in adults. We report a case in a 19-year-old woman who developed congestive heart failure induced by severe chronic hypocalcemia disclosing primary hypoparathyroidism. Complete regression of the clinical signs was achieved with vitamin-calcium treatment, but left ventricular systolic dysfunction persisted eight months after treatment.

Adult↗

Cardiac hydatid cyst revealed by complete heart block.

Hydatid cyst of the heart is an uncommon lesion. The infection is most common in sheep-raising areas of the world. We report a rare case of cardiac hydatid cyst revealed by complete heart block, which was removed with the patient under cardiopulmonary bypass. This case stresses the importance of echocardiography for the diagnosis of cardiac echinococcosis.

Adult↗

[Malignant mediastinal schwannoma in Recklinghausen's disease presenting as cardiac tamponade. Report of two cases].

The authors report two cases of Recklinghausen's disease admitted for cardiac tamponade. Two-dimensional echocardiography showed a pericardial tumour in addition to a compressive pericardial effusion. After pericardial drainage, the outcome was rapidly fatal. Histological examination confirmed the diagnosis of a malignant intrapericardial schwannoma. A review of the literature revealed the scarcity of mediastinal malignant schwannoma. Associated with Von Reckinghausen's disease in 2 to 13% of cases, the prognosis is poor. The presentation of malignant mediastinal schwannoma with cardiac tamponade remains very rare.

Adult↗

[Hydatic disease of the heart presenting with pericardial effusion. A case report].

The authors report a rare case of multiple mediastinal hydatid cysts which ruptured in a 48 year old man who presented with a pericardial effusion. The diagnosis was confirmed by 2D echocardiography, completed by CT scan and magnetic resonance imaging. The patient was operated as a semi-emergency and the outcome was good. This case underlines the rare pericardial involvement and the severity of the complications of cardiac hydatid disease.

Diagnosis, Differential↗

[Cardiac manifestations of Takayasu's arteritis: apropos of 5 cases].

PURPOSE: Cardiac manifestations of Takayasu's arteritis are rarely reported in the literature. However, these symptoms are not rare and when they do occur, they determine the disease prognosis. Due to its frequency, its severe nature, and even sometimes diagnosis failure, high blood pressure is the major cause of cardiac manifestations. More specific cardiac manifestations of either coronary, valvular, or more rarely, myocardial origin may also occur. METHODS: Analysis of five cases of Takayasu's arteritis and a literature review allowed evaluation of both the frequency and characteristics of this disease. RESULTS: Four female and one male patients presenting with symptoms of Takayasu's arteritis, according to Fiessinger's score, were evaluated. Diagnosis of cardiac disease was based on clinical, echocardiographic and angiographic criteria. Four patients had related high blood pressure. Valvular manifestations were present in all the patients. They included mitral insufficiency (1 case); aortic insufficiency (2 cases), and both mitral and aortic insufficiency (2 cases). Two patients showed clinical manifestations of a myocardiac disease, and another showed coronary signs. Treatment did not involve surgery, including only antihypertensive drugs, nitrites, and diuretics associated with digitalin in case of cardiac failure. The disease outcome, including a 5-18 year follow-up, involved symptom decrease in all the patients. CONCLUSION: Despite the rarity of cardiac manifestations in patients suffering from Takayasu's arteritis, symptoms of this disease should always be investigated, as these manifestations alter the prognosis. Aortic insufficiency is the most frequently encountered cardiac manifestation.

Adolescent↗

[Horton's disease presenting as a myocardial infarction].

The authors report the case of a 60-year-old man admitted for uncomplicated acute myocardial infarction. The history of persistent fronto-occipital headaches and palpation of bilateral tortuous temporal arteries with a decreased pulse suggested the diagnosis of temporal arteritis, particularly in the presence of marked laboratory signs of inflammation and the coronary angiograph findings. The diagnosis was confirmed by temporal artery biopsy. Treatment consisted of corticosteroid therapy, with a satisfactory outcome at three months. The diagnosis of temporal arteritis should be systematically suggested in patients over the age of 50 years, presenting with a marked inflammatory syndrome and recent-onset arterial disease. Similarly, any form of arterial disease occurring during treated temporal arteritis should initially be considered to be a secondary site of the arteritis, requiring intensification of corticosteroid therapy.

Adrenergic beta-Antagonists↗

[Frequency of improper diagnosis of hypertension].

The aim of this work is to estimate the real prevalence of hypertension in a population declared hypertensive by general practitioners. This prospective study has lasted 30 months from October 1994 to March 1997). It has concerned 2,151 patients that had been declared hypertensive by general practitioners. Each patient had 2 visits at 15 days interval. During each visit the blood pressure (BP) is measured 4 times at 5 min interval with a mercury tensiometer. The patient remains supine for 20 min. Patients declared normotensive on these 8 measurements are controlled once every 6 months. Those that are declared hypertensive are distributed in 2 groups: the patients that have a systolic blood pressure (SBP) superior to 160 mm of mercury (mmHg) and/or diastolic blood pressure (DBP) superior to 95 mmHg are treated with the habitual follow-up. Those that have a SBP and DBP between 140-160 mmHg and 90-95 mmHg have a control visit at the end of the first and the third month. After this period patients whose BP remains between 140-160 mmHg and 90-95 mmHg have an ambulatory blood pressure measurement (ABPM). This study included 1,635 women and 516 men. Average age was 54 +/- 11 years. The average of 8 measurements of SBP/DBP was 148.3 +/- 22.5/93 +/- 13 mmHg. After 8 measurements, out of 2,151 patients, 37.8% (841 patients) were declared normotensive and 62.2% (1,337 patients) had a SBP and/or DBP > 140/90 mmHg. This group was controlled after one month and 3 months. A subgroup (254 patients) was declared normotensive, and the 588 patients whose BP remained between 140-160 mmHg and 90-95 mmHg had an ABPM : 481 (48%) were then declared normotensive and 307 (52%) were declared normotensive patients. After repeated controls, with the use of ABPM, only 37.3% were truly hypertensive. This study confirms that a long follow-up is necessary before labelling a patients as hypertensive. BP can remain abnormal for weeks and months. A large group of "hypertensive" patients are normotensive people with a white coat effect or so labelled because of errors in technique or the absence of a sufficient delay so that BP returns to normal.

Aged↗