PubMed Health⌕ Search

Biomedical subjects

N Colavita

Publications and source records attributed to N Colavita.

At least 19 recordsLinked to original sources
PubMed2006

Magnetic resonance imaging evaluation of bone marrow changes in obstructive sleep apnoea syndrome in adults.

PURPOSE: The aim of this study was to evaluate bone marrow reconversion in patients with obstructive sleep apnoea syndrome (OSAS) by means of magnetic resonance imaging (MRI). To our knowledge, no explicit correlation between OSAS and such parameter has been documented in the literature. MATERIALS AND METHODS: During a 35-month period, 33 patients with a clinical diagnosis of OSAS, obese but without restrictive or obstructive ventilatory defects, were evaluated with MRI during wakefulness in all patients with T1-, PD- and T2-weighted sequences in the sagittal and axial plane within 1 week after polysomnography. RESULTS: MRI showed bone marrow reconversion in 33.3% of patients. Patients with bone marrow reconversion showed higher mean haematocrit (HT) values, lower mean nocturnal oxyhaemoglobin saturation, higher percentage of sleep time with oxygen saturation (SaO2) <90%, lower nadir, as well as greater neck adiposity and soft-palate lengthening compared with patients without bone marrow reconversion. Furthermore, in patients with bone marrow reconversion, haematocrit (HT) was negatively correlated with daytime arterial oxygen partial pressure (PaO2) and positively with arterial carbon dioxide partial pressure (PaCO2). CONCLUSIONS: In patients with OSAS, bone marrow reconversion is probably correlated with the severity of nocturnal desaturation. As bone marrow reconversion is, for unknown reasons, greater in adults younger than 40 years, MRI evidence of bone marrow reconversion could be useful in young individuals for the early diagnosis of sleep-disordered breathing and prevention of associated cardiovascular diseases.

Adult↗
PubMed1993

[Fibrous dysplasia of the skull. Radiologic diagnosis].

The authors examined 11 patients with fibrous dysplasia of the skull pointing out its radiologic features and preferential sites. Conventional radiology, CT and MR imaging were used. As for conventional radiology, tangential scans which of great value to depict the most typical morphologic patterns. Lesions of the skull base were most frequent in the sphenoid (7 of 11 cases), where 5 of 7 exhibited a sclerotic pattern. Bone changes in the skull vault were: mixed (3 cases), pagetoid (2 cases), "ground glass" (1 case) and lytic (1 case): none of these cases was of the sclerotic type. A typical feature of vault lesions was the widening of diploic space associated with expansion of the outer bone and integrity of the inner bone. Radiologic findings, often associated with suggestive clinical manifestations, always allowed a diagnostic hypothesis; histopathologic confirmation was needed only in a few cases (4 of 11 patients).

Adolescent↗
PubMed1989

Mucolipidosis II: correlation between radiological features and histopathology of the bones.

Twelve cases of Mucolipidosis II (I-cell disease) with a wide range of severity of skeletal involvement were studied. Pathological findings in two cases provided helpful information in understanding the radiographic features of dysostosis multiplex. Inhibition of the growth plate cartilage calcification and rickets-like lesions were observed in the metaphyses. Enhanced subperiosteal remodelling and paratrabecular fibrosis were also evident in the diaphyses. High levels of parathormone were found in one case. This finding supports the hypothesis that bone lesions may be secondary, at least in part, to damage in such viscera as the kidney and/or the liver and that they are mediated by vitamin D and parathormone.

Bone and Bones↗
PubMed1987

Premature epiphyseal fusion and extramedullary hematopoiesis in thalassemia.

The main skeletal abnormalities in beta-thalassemia are widening of medullary spaces, rarefaction of bone trabeculae, thinning of cortical bone, and perpendicular periosteal spiculation. Premature epiphyseal fusion (PEF) and extramedullary hematopoiesis (EH) are found, though more rarely. The incidence of PEF and EH in 64 patients affected by beta-thalassemia is reported. The different incidence of such complications in thalassemia major and intermedia is reported, and a possible correlation with transfusion regimen is also considered.

Adolescent↗
PubMed1987

Melorheostosis: presentation of a case followed up for 24 years.

The case of a woman affected by Melorheostosis of the left arm, who was followed for 24 years, is presented. After a brief review of the main clinico-radiological features and the most likely pathogenetic theory, the authors point out the slow but inexorable progression of the alterations and their localization, which is strictly limited to the dermatome supplied by a spinal nerve.

Female↗
PubMed1986

Does MURCS association represent an actual nonrandom complex of malformations?

The MURCS association was first suggested by Duncan in 1979 as a distinctive nonrandom association of congenital anomalies involving the Mullerian duct, the kidneys and the cervicothoracic spine. Two personal cases, highly resembling Duncan's description, are reported. In our opinion, they seem to support somehow the hypothesis that MURCS association should be considered as an autonomous pathological entity. The great phenotypical variability and the still unknown etiopathogenetic mechanism are particularly stressed.

Abnormalities, Multiple↗
PubMed1985

[Peritubal adhesions and hysterosalpingography].

Hysterosalpingography cannot directly show pelvic adhesions due to pelviperitonitis, salpingitis, perimetritis or parametritis. Nevertheless this method is able to evidence an eventual tubal involvement by adhesive tissue. Located pools of contrast medium around the tubae is a well known radiological sign, but not the only nor the most frequently one observed. If the adhesions include the proximal end of the tubae, the contrast pooling may be absent. This paper analyzes, in controlled series of patients with pelvic adhesions, all the hysterosalpingographic signs which can indicate an adhesive tubal involvement.

Adult↗
PubMed1984

An unusual kind of muscular and skeletal involvement in a heroin addict. A case report.

After a brief review of the infectious complications that frequently occur in heroin users, the authors report a case of chronic osteomyelitis affecting the ulnar diaphysis bilaterally. Musculo-cutaneous dystrophic lesions were also present and resulted in forced flexion of the distal phalanges of fingers 2-5. The most likely pathogenetic development discussed.

Adult↗
PubMed1984

Neonatal death dwarfism--a new form.

A new type of neonatal death dwarfism is reported. Although it resembles superficially the metatropic dysplasia group of diseases it has some distinctive radiographic features which help to delineate it as a separate entity.

Female↗
PubMed1984

[Prone position in hysterosalpingography].

The authors discuss the importance of prone hysterosalpingography to the aim of a careful tubal examination. Nearly all the complete or partial tubal obstructions, observed during supine hysterosalpingography, have been resolved by the simple prone position. The high percentage (91%) of successes, without pharmacological help, recommends the routine use of this simple method in all cases of doubtful tubal obstructions.

Fallopian Tube Diseases↗
PubMed1984

Skeletal changes in preterm infants: personal experience.

The incidence of skeletal changes in preterm low-birth-weight infants is rising. This is probably related to today's higher survival rate of these babies. The late positivity of biochemical data and the lack of clinical prognostic signs justify the role of radiology in such pathology. Radiology, however, although useful in detecting rachitic changes, seems to be less sensitive to minimal osteoporotic modifications, for which densitometric studies should be preferred. The authors report their personal experience in 8 cases of skeletal pathology in preterm infants and suggest a radiological follow-up of the skeleton from the 5th to the 12th week of life, whenever a densitometric method is not available.

Bone Diseases↗