Improved antiglobulin tests to detect difficult antibodies: detection of anti-Kell by LISS.
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Biomedical subjects
Publications and source records attributed to N Cook.
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The use of cryosurgery applied to the sphenopalatine area (artery and ganglion) plus the superficial temporal and occipital branches of the external carotid artery has proven worthwhile in a majority of patients in whom this procedure has been used since 1968. Experience includes almost 700 procedures in more than 500 patients who have answered to follow-up. The procedure is not a major operation, is repeatable and, until the ideal drug is discovered, offers a better than average change for definite improvement in vascular headache.
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Specimens of beef bone were analyzed for thermal conductivity and thermal capacity. The thermal conductivity was about 7 X 10(-4) cal/cm/sec/degrees C, that is about the same as for other tissues. As regards thermal capacity, the determination of 0.73 cal/cm2/degrees C also was similar to that in other tissues. Both thermal conductivity and capacity were isotropic with respect to the layer of epiphyseal cartilage, and the orientation of bony trabeculae. Thermal probes were devised heated either by water or by electric current to destroy localized volumes of bone, as in surgery. To achieve necrotizing temperatures, the sizes of such probes and the times of application of heat were determined.
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BACKGROUND: Cancer patients are at risk of venous thromboembolism (VTE). Currently, management of these patients is based on studies performed in the general population. AIMS: To determine whether the natural history of VTE in cancer patients differs sufficiently from patients in general such that a specific management approach is required. METHODS: A retrospective survey was conducted using case records from three tertiary referral hospitals (1993-2001). One hundred and forty-seven VTE patients with cancer and 82 control patients matched for age and gender were followed for a median of 24 months (0-104 months). RESULTS: The overall prevalence of cancer among patients with VTE was 19.3% (vs 4% in patients with arterial thromboembolic events). In the follow-up groups, cancer conferred a significantly worse functional status, although other risk factors for VTE were similar. Proximal sites of VTE were twice as common in cancer as in non-cancer patients. The majority of patients in both groups were treated with oral anticoagulants. Complications were more common in cancer patients (40% vs 23%) and occurred more frequently despite apparently adequate anticoagulation. Following VTE, cancer patient survival (median 4.1 months, 127 deaths) was markedly worse than non-cancer patients (median not reached, eight deaths). Thirty-five cancer deaths occurred within 5 weeks of VTE. Eleven deaths in cancer patients were directly related to VTE compared to three in patients without cancer. CONCLUSIONS: Cancer patients with VTE fare extremely poorly compared to the general hospital population. Prospective treatment studies, specifically in cancer patients with VTE, are needed.
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As central venous catheters (CVCs) become more widely used in today's healthcare environment, nurses require expert knowledge in relation to CVC maintenance to prevent complications and maximize efforts to optimize the individual's health status. This is especially so since CVCs have begun to be used outside intensive care units, e.g. in general wards, and can be associated with high incidences of infection, occlusion and subsequent compromise in patient health. Nurses are responsible for the maintenance and use of central access devices, such as CVCs, resulting in a need for literature specific to the nursing aspects of CVC management. This article addresses many nursing issues pertaining to care of the central line, focusing on evidence- and research-based literature, and also reviews the literature to make recommendations for practice.
Testicular cancer represents a significant threat to the health of males aged between 15 and 34 years. As there has been significant focus on early detection of cancers in order to intervene at the earliest opportunity to improve treatment outcomes, the detection of testicular cancer through secondary prevention merits careful consideration. This article discusses two health promotion approaches to dealing with the subject of optimizing men's health: the merits and disadvantages of testicular self-examination education; and screening for testicular tumours in high-risk populations. Recommendations for adapting traditional approaches are also discussed.