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N D DeBruhl

Publications and source records attributed to N D DeBruhl.

17 recordsLinked to original sources
PubMed1997

Breast calcification and mass detection with mammographic anode-filter combinations of molybdenum, tungsten, and rhodium.

PURPOSE: To determine whether contrast loss on mammograms obtained with tungsten (W)-molybdenum (Mo), rhodium (Rh)-Rh, and W-Rh anode-filter units affects calcification and mass detection relative to that on mammograms obtained with Mo-Mo anode-filter units. MATERIALS AND METHODS: Three unfixed cadaveric breasts of 4.0-, 5.5-, or 7.0-cm thickness were imaged with three mammographic units with Mo-Mo, W-Mo, Rh-Rh, and W-Rh anode-filter combinations. Calcification clusters (<300 microm in diameter) and masses (0.5-1.2 cm) placed on the cadaveric breasts simulated abnormal mammograms. Thirty-five images without and 57 images with added calcifications and masses were acquired with a 180-speed screen-film system and interpreted by four mammographic specialists. With a 150-speed screen-film system, 10 normal images and 30 abnormal images with added calcifications were obtained with Mo-Mo and Rh-Rh equipment and read by three of the four radiologists. RESULTS: For the 180-speed system, there were statistically significant differences (P < .05) in detection of calcifications on Mo-Mo images compared with W-Mo, Rh-Rh, and W-Rh images. These differences disappeared with the 150-speed system. For mass detection with the 180-speed system, W-Rh was significantly better than Mo-Mo (P = .02). CONCLUSION: Dose savings and increased penetration with Rh-Rh and W-Rh anode-filter combinations may decrease calcification detection if fast screen-film systems are used, but mass detection may be improved.

Aged↗
PubMed1996

Mobile mammography: results of a national survey.

PURPOSE: to learn about mobile mammography in the United States. MATERIALS AND METHODS: A survey of 82 questions was designed, pilot tested, and sent to mobile mammography facilities. The questions addressed many aspects of mobile programs, including administrative, financial, equipment, personnel, film processing, quality assurance, and communication of results. RESULTS: Of the 367 facilities that were mailed surveys, 159 facilities completed the survey, and 30 (19%) of those had discontinued their mobile programs. Seventy-six of 158 (48%) mobile facilities had performed mobile mammography for 1-5 years, and 69 of 158 (44%) had performed mobile mammography for more than 5 years. Seventy-two of 156 (46%) facilities were hospital-owned, and 25 of 156 (16%) were radiologist-owned. One hundred seven of 159 (67%) mobile facilities performed screening only. One hundred fourteen of 152 (75%) facilities charged +80.00 or less for screening. Mobile facilities averaged 20 examinations per day and served diverse populations. Sixty-seven of 159 (42%) facilities accepted self-referred women. Thirty-one percent of the facilities performed on-board processing. Only 71 of 149 (47%) facilities were financially profitable or breaking even, but 112 of 154 (73%) facilities would undertake a mobile project again. CONCLUSION: Mobile programs provide an opportunity to increase access to screening mammography, but they face many obstacles.

Data Collection↗
PubMed1996

Mammographically guided fine-needle aspiration cytology of the breast: reducing the rate of insufficient specimens.

OBJECTIVE: The purpose of our study was to reduce the rate of insufficient specimens from fine-needle aspiration cytology (FNAC) of impalpable mammographically detected breast lesions. SUBJECTS AND METHODS: Our previous rate of insufficient specimens for FNAC was 27%. We implemented the following strategies to reduce this rate and improve accuracy: retraining of radiologists in FNAC procedures, more vigorous sampling, on-site evaluation of specimens by cytopathologist or cytotechnologist, exclusive use of stereotaxic guidance, stereotaxic equipment calibration program, and verification of initial needle placement. RESULTS: Of 77 patients with impalpable abnormalities who underwent FNAC with the new protocol, six (8%) had insufficient specimens for cytologic diagnosis: Four were incorrectly judged to contain sufficient material at the time of FNAC, one refused to complete the FNAC, and one had a vasovagal reaction. Of the six cases with insufficient specimens, four were benign at biopsy, one was malignant, and one was determined to be benign on the basis of mammographic stability. CONCLUSION: Modification of techniques and implementation of a quality assurance program can significantly improve the insufficient specimen rate for FNAC. Correlation of mammographic and cytologic findings also improves the management of these cases.

Adult↗
PubMed1995

Evaluation of autogenous tissue breast reconstruction using MRI.

Recent controversy encountered with silicone breast implants has increased the use of autogenous tissue for breast reconstruction following mastectomy. Surveillance of patients who have undergone autogenous tissue reconstruction is important in the evaluation of recurrent or new cancer. Magnetic resonance imaging (MRI) has proven to be a useful technique in the delineation of soft tissues and provides excellent resolution. Recently, MRI has been reported to be a valuable diagnostic imaging modality for the evaluation of augmented breast implant patients with regard to implant rupture detection, silicone granuloma identification, and silicone gel migration delineation. In this study, various autologous tissue donor sites currently available for breast reconstruction were imaged by MRI. The following donor flaps were included: fleur-de-lis, TRAM, gluteal, and tensor fasciae latae. A total of 10 clinical cases were investigated. The anatomic basis of each flap type is illustrated, and various tissue components of flap tissue (skin, fat, and muscle) are demonstrated on MRI scan. Anatomic knowledge of autogenous tissue types and MRI appearance of the flap-breast-chest-wall interface are critical in the surveillance and follow-up of breast cancer patients.

Breast↗
PubMed1994

Silicone implant rupture diagnosis using computed tomography: a case report and experience with 22 surgically removed implants.

Silicone elastomer shell rupture is a complication of silicone implants. To date, the rate of implant rupture has not been well documented. Magnetic resonance imaging and sonography are noninvasive breast implant imaging modalities that have been shown to be useful in evaluating the integrity of implants. We present a case of rupture detection using a follow-up computed tomographic (CT) scan of a breast cancer patient, which prompted us to use CT scans to evaluate explants of patients undergoing implant removal surgery. The purpose of the investigation was to evaluate the effectiveness of CT scan in detecting rupture. CT scan was performed on 22 explants with intact capsules, for which 17 ruptures were confirmed: 16 true-positive ruptures, 5 true-negative ruptures, O false-positive ruptures, and 1 false-negative rupture were identified. CT scan was shown to be highly sensitive and specific in rupture detection, comparable to magnetic resonance imaging. Although CT scans are consistently reliable, patients are exposed to ionizing radiation; therefore, it is not recommended for patients with augmentation mammoplasty. This study characterizes the appearance of implant rupture on CT scan, which may be useful in evaluating breast cancer patients reconstructed with silicone implants.

Breast Implants↗
PubMed1994

Comparative silicone breast implant evaluation using mammography, sonography, and magnetic resonance imaging: experience with 59 implants.

With the current controversy regarding the safety of silicone implants, the detection and evaluation of implant rupture are causing concern for both plastic surgeons and patients. Our study obtained comparative value analysis of mammography, sonography, and magnetic resonance imaging (MRI) in the detection of silicone implant rupture. Twenty-nine symptomatic patients (total of 59 silicone implants) were entered into the study. Intraoperative findings revealed 21 ruptured implants (36 percent). During physical examination, a positive "squeeze test" was highly suggestive of implant rupture. Mammograms were obtained of 51 implants (sensitivity 11 percent, specificity 89 percent). Sonography was performed on 57 implants (sensitivity 70 percent, specificity 92 percent). MRI was performed on 55 implants (sensitivity 81 percent, specificity 92 percent). Sonographically, implant rupture is demonstrated by the "stepladder sign." Double-lumen implants may appear as false-positive results for rupture on sonography. On MRI, the "linguine sign" represents disrupted fragments of a ruptured implant. The most reliable imaging modality for implant rupture detection is MRI, followed by sonogram. Mammogram is the least reliable. Our study supports the clinical indication and diagnostic value of sonogram and MRI in the evaluation of symptomatic breast implant patients.

Breast Diseases↗
PubMed1994

Silicone breast implant ruptures in an animal model: comparison of mammography, MR imaging, US, and CT.

PURPOSE: To determine the most accurate imaging modality for detection of silicone implant ruptures. MATERIALS AND METHODS: Forty single-lumen silicone implants were surgically placed in 20 rabbits. Each rabbit received one intact and one ruptured implant and was examined with mammography, magnetic resonance (MR) imaging, ultrasound (US), and computed tomography (CT). Five radiologists reviewed all images in a random fashion and graded each for rupture. The radiologist who performed US also graded her impression during examination with US. Receiver operating characteristic (ROC) analysis was performed. RESULTS: MR imaging and CT were the most accurate modalities in detection of implant ruptures, with areas under the ROC curves (Az) of .95 and .91. Mammography and US were statistically significantly inferior, with Az of .77 for each (P < .05). CONCLUSION: MR imaging and CT are statistically more accurate than US and mammography for detection of intracapsular silicone implant ruptures when only the images are reviewed.

Animals↗
PubMed1994

Linguine sign at MR imaging: does it represent the collapsed silicone implant shell?

One intact and one ruptured single-lumen implant were surgically placed in a rabbit. Magnetic resonance (MR) imaging was performed before and after surgical removal, and the ruptured implant was imaged after removal of the implant shell. Multiple curvilinear hypointense lines (linguine sign) were present in the MR images of the ruptured implant and of the implant shell alone immersed in saline solution but not in the image of the free silicone. The collapsed implant shell in a ruptured silicone implant does cause the linguine sign.

Animals↗
PubMed1994

Silicone breast implant rupture: comparison between three-point Dixon and fast spin-echo MR imaging.

OBJECTIVE: This study was designed to compare the three-point Dixon technique with our present MR protocol incorporating T2-weighted fast spin echo and fast spin echo with water suppression to detect ruptured silicone breast implants. SUBJECTS AND METHODS: Eighty-two symptomatic women with silicone breast implants were examined with both the three-point Dixon technique and fast spin-echo MR sequences. Of these patients, 41 had surgery to remove their implants. Four radiologists reviewed the images from only those patients who had surgery and graded each for rupture by using a scale of 1-5. Receiver-operating-characteristic analysis was performed. RESULTS: Of 81 implants removed, 18 were ruptured. Silicone implant ruptures were identified more frequently on the fast spin-echo sequence than on the three-point Dixon sequence, with areas under the ROC curves of .95 and .84, respectively. Although the difference was not statistically significant, the sensitivity for detecting silicone implant rupture was 89% for the fast spin-echo sequence and 61% for the three-point Dixon sequence. The specificity was 97% for both sequences. CONCLUSION: Silicone implant ruptures were detected more frequently with fast spin-echo MR sequences than with the three-point Dixon technique, although the difference was not significant. The greater spatial resolution used for the fast spin-echo sequence partially accounts for the difference in detection of implant ruptures in this study.

Breast↗
PubMed1993

MR imaging of silicone breast implants: comparison of different coil arrays.

To determine the optimal coil and patient position for magnetic resonance imaging of patients with silicone breast implants, images obtained with body, circular surface, flexible, single shoulder, and dual shoulder coils in various numbers of patients were compared with regard to signal-to-noise ratio (S/N), decay of signal intensity, resolution, and key area coverage. Images obtained with the dual shoulder coil and prone position, with a customized positioning device, gave the best S/N, resolution, and coverage of the breasts and axillae.

Breast↗
PubMed1993

Silicone breast implants: US evaluation.

PURPOSE: To determine the value of breast ultrasonography (US) in the assessment of silicone breast implants for rupture. MATERIALS AND METHODS: Seventy-four women with local or systemic symptoms related to silicone implants underwent breast US. Of these, 28 underwent surgical removal of the implants. RESULTS: Of 57 implants removed, 37 were intact. The most reliable sign of an intact implant was an anechoic interior, although reverberation artifact and radical folds could be seen. Of 20 ruptured implants, 16 were intracapsular and four were extracapsular ruptures. The most reliable US sign of rupture was echogenic, horizontal ("stepladder") lines (14 of 20 ruptures). Two of the four extracapsular ruptures were accurately identified as echogenic nodules outside the implant; two were false-negative findings. Three intracapsular ruptures identified at US were false-positive; six were false-negative. Overall sensitivity for rupture was 70%, specificity was 92%, positive predictive value was 82%, and negative predictive value was 85%. CONCLUSION: Breast US is capable of depicting intracapsular and extracapsular rupture of breast implants.

Adult↗
PubMed1993

MR imaging of the breast in patients with silicone-gel implants: spectrum of findings.

Because of recent concerns about the potential dangers of rupture and leakage of silicone-gel implants, radiologists are often requested to evaluate the integrity of normal breast implants. Clinical studies suggest that MR imaging can accurately depict implant rupture. The purpose of this pictorial essay is to illustrate the spectrum of MR appearances of breasts in patients with silicone-gel implants. Types of prostheses range from the more common single-lumen silicone-gel implants to the rare foam-filled implants. Recognition of the variable appearance of intact implants is emphasized in order to distinguish these from intracapsular or extracapsular ruptures. Finally, we briefly review various investigational MR sequences designed to improve the evaluation of the integrity of silicone-gel implants and the localization of free silicone. This article is based on our experience in performing MR imaging in more than 350 patients with breast implants. In more than 50% of these patients, the MR imaging findings have been correlated with surgical and pathologic findings.

Adult↗
PubMed1992

Silicone breast implants in vivo: MR imaging.

This study was designed to evaluate pulse sequences and patient positioning for MR imaging of silicone breast implants in patients. One hundred forty-three patients (281 silicone implants) underwent imaging over a 21-month period. The combination of a T2-weighted fast spin echo technique (SE), T2-weighted fast SE with water suppression, and T1-weighted SE with fat suppression is recommended to reliably differentiate silicone from other breast tissues and to identify intracapsular and extracapsular ruptures or leaks. Seventy of the 143 patients underwent removal of their silicone implants. The sensitivity for detection of silicone implant rupture was 76%, with a specificity of 97%. Positioning the patient prone improved image quality.

Adult↗
PubMed1992

Strategies for implementation and quality assurance for mammographic screening.

Compliance with screening mammography guidelines is affected by complex factors, including cost, accessibility, education, and attitudes of referring physicians. High-volume mammography facilities have lower fees and higher quality. Quality assurance is the focus of the voluntary American College of Radiology Mammography Accreditation Program, and over half of all mammography units are accredited. Nonetheless, pressure for mandatory quality standards is increasing. Mobile mammography reduces costs and increases access, but it presents challenges in financing and quality assurance. These screening issues, especially quality assurance, are not taught adequately in radiology residency training programs. Yet public awareness of the benefits of early detection has resulted in more lawsuits for failure to diagnose and delay in diagnosis. Preventive measures reduce medicolegal risks. On a personal level, the psychologic trauma of screening mammography is greater than was previously suspected. However, associated anxiety and stress do not seem to affect compliance with screening guidelines adversely.

Female↗
PubMedDate not supplied

Multifeature analysis of Gd-enhanced MR images of breast lesions.

The objective of this study was to determine whether linear discriminant analysis of different independent features of MR images of breast lesions can increase the sensitivity and specificity of this technique. For MR images of 23 benign and 20 malignant breast lesions, three independent classes of features, including characteristics of Gd-DTPA-uptake curve, boundary, and texture were evaluated. The three classes included five, four and eight features each, respectively. Discriminant analysis was applied both within and across the three classes, to find the best combination of features yielding the highest classification accuracy. The highest specificity and sensitivity of the different classes considered independently were as follows: Gd-uptake curves, 83% and 70%; boundary features, 86% and 70%; and texture, 70% and 75%, respectively. A combination of one feature each from the first two classes and age yielded a specificity of 79% and sensitivity of 90%, whereas highest figures of 93% and 95%, respectively, were obtained when a total of 10 features were combined across different classes. Statistical analysis of different independent classes of features in MR images of breast lesions can improve the classification accuracy of this technique significantly.

Breast Diseases↗
PubMedDate not supplied

Residual silicone detection using MRI following previous breast implant removal: case reports.

The current controversy surrounding the safety of silicone gel breast implants has resulted in an increasing number being removed. Although previous reports have suggested that remnants of the implant capsule are reabsorbed after explantation surgery, the persistence of the capsule in fact may be associated with implant fragments and silicone gel leakage. In this study we have used magnetic resonance imaging (MRI) to identify residual silicone gel and silicone granulomas following the removal of silicone gel breast implants. Four representative clinical case reports are presented. These patients, who had residual silicone present in their bodies, presented to us with breast pain, palpable masses, or abnormal calcific mass densities apparent on a mammogram. High-resolution MRI images were found to be helpful in identifying local and remote collections of silicone gel, silicone granulomas, and residual capsules that were incompletely removed from previous explantation surgery. MRI breast images demonstrated high resolution and provided the accurate anatomical locations of residual silicone gel and silicone granulomas in all the regions of breast parenchyma, chest wall muscles, and axillae. Patients with persistent local symptoms following explantation surgery may benefit from an evaluation of the breast using MRI.

Adult↗