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N D Koval'chuk

Publications and source records attributed to N D Koval'chuk.

9 recordsLinked to original sources

[Radiation doses to patients after the use of 99mTc-pyrophosphate and 113mIn-indifor].

The doses of irradiation of patients during the use of 99mTc-pyrphotech and 113mIn-indifor have been defined on the basis of their pharmacokinetics. The data has been obtained with the use of radiometer of human radiation, the method of organs screening during radiometry, and of the gamma-camera and blood samples radiometry. The calculations have been performed in accordance with the known method based on the heterogeneous model of the "standard" human. In the dose calculations for bone tissue and for the red marrow the dosimetry model is used and the values of absorbed fractions recommended by the ICRP. The absorbed and equivalent doses of irradiation of different organs and systems in human organism have been defined. The required values of quality index have been calculated using the spectrum of absorbed dose on the scale of linear transfer of energy for all radiations of the analysed nuclides. The obtained values of efficient equivalent dose are 8.6 and 16 MeV/MBq for 113mIn-indifor and 99mTc-pyrphotech correspondingly.

Bone Marrow↗

[Pharmacokinetic substantiation of the use of 111In-citrate in bone marrow studies].

Soviet radiopharmaceutical 111In-citrin has been studied to define its possible application for marrow visualization. 111In-citrin has been shown to accumulate in the red marrow, parenchymal organs and to be excreted from animal organism by urinary system predominately. 111In-citrin has advantages in defining the nuclide concentrations in marrow blood and serum as compared with colloid preparations and 111In-chloride. 111In-citrin is supposed to be an adequate radiopharmaceutical preparation for visualization of the red marrow.

Animals↗