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N D Nikiforov

Publications and source records attributed to N D Nikiforov.

11 recordsLinked to original sources
PubMed1992

[Clinico-morphological characteristics of intrahepatic cholestasis in hepatitis A and delta infection].

Clinical and morphological characteristics were studied for a course of acute viral hepatitis A and delta with long-term cholestatic syndrome in asymptomatic carriers of HBsAg. 149 patients with moderate disease were examined, 53 of them had long-standing cholestasis syndrome. 96 viral hepatitis patients free of cholestasis served control. It is believed that the emergence of long-term intrahepatic cholestasis may be due to the following mechanisms of sinusoid lumina as a result of a drastic enlargement of multinuclear hepatocytes, hyperplasia and hypertrophy of Kupffer's cells. impaired binding of bilirubin in zone III of hepatic acinus. In cholestatic form of hepatitis A there occurs more pronounced reduction of sinusoid volume compared to other variants of viral hepatitis run.

Cholestasis, Intrahepatic↗
PubMed1991

[Delta hepatitis].

Explore the source record for details and available documents.

Carrier State↗
PubMed1989

[Microcirculatory function in various clinical forms of HB and HD viral infections].

Bulbar microphotographic vasography was used in 100 patients with different clinical patterns of HBV and HDV infections to study microcirculation over time. The data obtained were correlated to the data of the immunoassays. The relationship between microcirculatory disorders recordable during HBV and HDV infections and immunopathological responses and conditions occurring in those infections is under discussion.

Acute Disease↗
PubMed1988

[Microcirculatory function in viral hepatitis A and B].

Microcirculation was studied over time in 51 patients with acute viral hepatitides types A and B using bulbar microphotographic vasography. The results were compared with some immunological indices (the blood level of circulating immune complexes, the platelet aggregation test). The expression of microcirculatory changes correlated both with a type of virus hepatitis and the severity of disease. The relationship of disorders in the system of microcirculation with immune factors, in particular with immunopathological reactions developing during HBV infections, was discussed.

Adolescent↗
PubMed1986

[Free and bound Brucella antigen and the level of circulating immune complexes in brucellosis patients].

The aggregate hemagglutination test has been shown to be a highly sensitive and specific method for the detection of infectious antigenemia in different forms of brucellosis, permitting the determination of free Brucella antigen in 34% of patients with the acute form of the disease and in 53% of patients with the chronic course of brucellosis. The results of the determination of the quantitative level of circulating immune complexes (CIC) indicate that in the acute form of the disease their level exceeds the CIC level observed in the chronic course of brucellosis. The preliminary dissociation of CIC in the patients' blood sera has been found to increase the overall release of Brucella antigen to 80%.

Agglutination Tests↗