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Biomedical subjects

N Demmler

Publications and source records attributed to N Demmler.

13 recordsLinked to original sources
PubMed1983

[Trials in pressure regulation with metipranolol eyedrops in special forms of glaucoma in ophthalmologic practice].

This paper presents the results of a study on the effect of Metipranolol eye drops (Betamann) in 10 patients. The drops were tested with the following forms of glaucoma: glaucoma associated with alpha-kia, neovascular glaucoma, exfoliative glaucoma, pigmentary glaucoma, juvenile glaucoma. Some patients required treatment in combination with miotics. Metipranolol eye drops reduced intraocular pressure by about 15 percent for a prolonged period of time. The pressure-lowering effect was maintained during an observation period of twelve months. Visual acuity and visual fields were constant. The drug was tolerated well subjectively by almost all the patients.

Adrenergic beta-Antagonists↗
PubMed1983

[Increase in visual field defects under long-term timolol treatment in patients with open-angle glaucoma - observations from an ophthalmology practice].

The authors report on 6 patients with open-angle glaucoma who were treated with Timolol eye drops for 2 years. During this period the intraocular pressure was normal at all times. In spite of this a deterioration in visual fields occurred, in some of the cases associated with reduced vision. It is emphasized that these patients form part of a larger group comprising 30 individuals. In the remaining 24 patients no deterioration of the visual field or vision was found during the 2 years of treatment with Timolol.

Aged↗
PubMed1981

[Effect of corticoids on protein concentration in rabbit aqueous humor after argon laser surgery of the iris (author's transl)].

A high dose of corticoid premedication was applicated intramuscularly five hours before laser surgery. Following laser coagulation of the pigmented iris the protein concentration in the aqueous humor was measured every hour. The initial increase in protein concentration was found to be lower than in earlier experiments without premedication. In contrast to earlier results without corticoid premedication, the reaction of the untreated contralateral eye was suppressed.

Animals↗
PubMed1980

[Treatment of glaucoma with beta receptor blockers].

We report the possibility of treatment with beta-adrenergic blocking agents in glaucoma-therapy. In open-angle glaucoma the therapy with beta-adrenergic blocking agents is often the best one. The combination of beta-adrenergic blocking agents with miotics is the therapy of choice in the treatment of closure-angle glaucoma. In special forms of glaucoma it is necessary to decide if the best therapy is the treatment with beta-adrenergaic blocking agents alone or a combined treatment of beta-adrenergic blocking agents with miotics. The beta-adrenergic blocking agent timolol (Chibro-Timoptol) and bupranolol (Ophtorenin) lower in the intraocular pressure to a greater extent than other beta-adrenergic blocking agents. Timolol eye drops and bupranolol eye drops are therefore the best beta-adrenergic blocking agents in therpay of glaucoma.

Adrenergic beta-Antagonists↗
PubMed1980

[Effect of long-term administration of timolol eye drops in open-angle glaucoma (author's transl)].

The authors report on ten patients with unstabilized open-angle glaucoma who were treated for up to six months with Timolol eye drops. A significant lowering of intraocular pressure was recorded throughout the treatment period. There was no evidence of deterioration of visual field or acuity. Subjective tolerance was good except in one patient who suffered temporarily from slight tachycardia.

Aged↗
PubMed1980

[Treatment of narrow-angle glaucoma with timolol (author's transl)].

The authors report on seven patients with narrow-angle glaucoma treated for up to six months with Timolol eye drops. Prior to treatment with Timolol the patient's eyes had remained unregulated despite miotics therapy, or it had been impossible to continue with miotics due to subjective intolerance. Timolol eye drops achieved a significant lowering of pressure in all seven patients and satisfactory pressure stabilization was achieved either with Timolol eye drops alone or in combination with pilocarpine or Carbachol eye drops. In one patient who had unregulated glaucoma and who was on Carbachol/acetazolamide therapy, satisfactory stabilization was achieved by additional application of Timolol.

Aged↗
PubMed1980

[Polyglycolic acid suture in strabismus surgery (author's transl)].

We report on 60 patients who underwent altogether 100 operations on their eye muscles, either recession or resection of a lateral rectus muscle, or both operations together. All muscles were sutured with 5-0 Dexon, and the conjunctivae with 7-0 Dexon. The postoperative reaction was studied. This suture material produces a good tissue reaction. Tying and knotholding qualities are also good.

Child↗
PubMed1980

[Long-term treatment of open-angle glaucoma with bupranolol eye drops (author's transl)].

In this study we examined the effect of Bupranolol eye drops on 10 patients with open-angle glaucoma. Treatment extended over six months. Bupranolol eye drops lowered intraocular pressure by about 15% over a prolonged period. Some patients needed treatment in combination with miotics. Visual acuity and visual fields remained constant. As a rule, Bupranolol was tolerated well by the patients

Adult↗
PubMed1980

[Long-term treatment of angle-closure glaucoma with bupranolol eye drops (author's transl)].

In this study we report on the effect of Bupranolol eye drops on 10 patients who, prior to treatment, experienced decompensation of their glaucoma in spite of the use of miotics or who were not given biotics treatment because of their occupation or because of severe subjective complaints. Treatment with Bupranolol is given for six months and results in clear reduction of intraocular pressure in all patients, so that satisfactory control can be achieved with Bupranolol eye drops either alone or in combination with a miotic agent. As a rule, Bupranolol is tolerated well by all patients.

Adult↗
PubMed1975

[Orbital decompression (author's transl)].

Decompression of the orbit for retro-orbital haematoma is not usually performed. On the other hand it is recommended when ophthalmoscopy shows impending thrombosis secondary to a massive orbital haematoma. In such cases both surgical decompression of the orbit and splitting of the optic nerve sheath should be done. The indications for the surgical exposure of the optic canal are: 1. When there is progressive change on perimetry of the visual fields; 2. When there is radiological evidence of narrowing of the optic canal; 3. When there is papilloedema. Because of the magnitude of the surgery it is only rarely utilized, and a conservative management is most frequently better.

Decompression↗