Despite substantial advances in breast cancer treatment, mortality from this disease remains high. While adjuvant chemo-hormonal therapy has significantly improved survival, breast cancer still claims the lives of more than 45,000 American women each year. This article is a brief review of various modalities used in the management of breast cancer, including adjuvant and neoadjuvant therapy, treatment for advanced disease, dose intensification, and autologous bone marrow transplantation.

Antineoplastic Combined Chemotherapy Protocols↗

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Abdominal computed tomography in macroglobulinemia (Waldenström's disease). Report of a case.

The findings at abdominal computed tomography (CT) in a patient with primary macroglobulinemia (Waldenström's disease) are reported. CT was of special value in monitoring the extent of the disease in the abdomen and the response to treatment. At the first examination the patient had changes in both the reticuloendothelial system and the small bowel. The prompt disappearance on treatment of the small bowel changes proves that these changes were due to a high plasma viscosity syndrome. The slow response on the liver, spleen and lymph nodes suggests lymphomatous engagement. Although the primary method to diagnose Waldenström's disease is through laboratory tests, CT is of use in monitoring the abdominal involvement, especially the response to treatment.

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