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Biomedical subjects

N Doganov

Publications and source records attributed to N Doganov.

At least 19 recordsLinked to original sources

[The dynamics and trends in surgical delivery at the Maternity Home of the State Institutional Hospital].

The study discusses the frequency of operative obstetric deliveries (cesarean section, forceps extraction and vacuum extraction) over a period of 18 years from 1976 till 1993. A total of 100,545 deliveries with 100,192 livebirths took place during this period with a decrease of the annual number of deliveries in the last years. The frequency of the various kinds of operative deliveries shows different tendencies. The frequency of cesarean section has increased from 4.87 per cent in 1976 to 19.58 per cent in 1993, this increase being particularly marked during the last 6 years. Meanwhile the vaginal operative deliveries have decreased their frequency. The decrease of forceps extraction is from 4.33 to 2.22 per cent (steadily about 2 per cent during the last years). The frequency of vacuum extraction has dropped from 1.89 per cent to 0 by the end of the 1980 and the beginning of the 1990. The tendencies of the development of obstetric operations are analysed as well as their influence on perinatal outcome.

Bulgaria

[The treatment of urinary stress incontinence with the sling and Pereyra's suspension].

Patients with proven stress incontinence were subjected to surgical treatment which combined both sling and Stamey-Pereyra techniques. A 3-4 cm long and 1,5-2 cm wide sling of Bulgarian polyamide mesh was placed under the urethrovesical junction using a small vaginal incision. Two long polyamide sutures were tied to either end of the mesh and were retrieved from the vagina to the abdomen by Pereyra needle inserted through two small suprapubic incisions and guided by the vaginal forefinger. The technique of the procedure is described. A total number of 27 patients were operated on. Two of them has their suspending sutures cut postoperatively because of prolonged urinary retention. The remaining 25 were continent. The technique proposed combines the advantages of the sling procedures (high efficiency especially in cases of severe and recurrent incontinence) and the simplicity of Stamey-Pereyra suspension technique. On the other hand the Bulgarian polyamide mesh showed very good qualities. No infection, rejection or sling erosion were observed.

Adult

[The role of serum beta-HCG levels for the diagnosis of ectopic pregnancy].

The study includes 56 cases of women admitted at Second gynaecology clinic of the University Maternity Hospital Sofia with evidence or suspicion of having an ectopic pregnancy who had their serum beta-HCG levels determined quantitatively. 27 of them showed no beta-HCG in their sera and none turned out to have pregnancy, neither intrauterine nor ectopic. All cases of ectopic pregnancies (a total of 20) were associated with detectable beta-HCG levels in the serum. The great diagnostic value of serum beta-HCG is emphasized in the cases of old disturbed ectopic pregnancies accompanied by mild and uncommon symptoms and very low beta-HCG levels. In case of unruptured pregnancies or tubal rupture the diagnosis is verified before the result is available by the clinical and sonographic data. On the other hand the high sensitivity of the method leads to an increased number of cases with elevated beta-HCG in which the location of the pregnancy cannot be proven. The precise quantitative evaluation of serum beta-HCG enables us to follow the tendency of beta-HCG which may according to the clinical manifestations warrant invasive diagnostic procedures or just observation without active interference.

Abortion, Spontaneous

[The static and dynamic profiles of urethral pressure in women with stress incontinence and in healthy controls].

The study presents the results of urethral pressure profile measurements in 3 groups of women: continent nulliparous, continent parous and stress incontinent women. The maximum urethral closure pressure, the functional urethral length and the length of continence zone are compared. The healthy control groups (both parous and nulliparous) show much higher maximum urethral closure pressures than those mentioned in literature. No difference is evident between continent parous and continent nulliparous which suggests that vaginal delivery at term does not necessarily impair urethral sphincteric function. On the other hand women with similar age and parity with stress incontinence have a marked decrease of maximum urethral closure pressure at rest and demonstrate inability to increase it by volitional contraction of the pelvic floor. These findings support the idea of the leading role of sphincteric incompetence in stress incontinence. The functional urethral length and the length of continence zone show no significant differences among the investigated groups which implies that they are of no importance for the occurrence of stress incontinence.

Adolescent

[4 cases of botryoid sarcoma].

The authors describe the rare botryoid sarcoma--histomorphology, clinic, diagnosis, treatment and prognosis with a contribution of 4 own cases at the age up to 18 years. They indicate the difficulties in the establishment of the diagnosis-early clinical and histological-in three of the cases the histological examination did not establish immediately the exact diagnosis--the material was considered as "granulation tissue" or "fibroma mole". The results of the treatment are summarized as well as the choice of therapeutic methods and drugs. The applied therapeutic scheme consists of radical hysterectomy with systemic pelvic lymph dissection and postoperative chemotherapy. The described four cases are alive at the present moment and without data for tumourous relapse--respectively 11 years and 2 months, 3 years and 4 months, 2 years and 8 months after establishment of the diagnosis.

Adolescent

[Clinical trial of the laksafer preparation on patients following gynecological operations].

An original Bulgarian phyto-preparation laxafer was used in 97 women, operated for gynecological complaints, with the aim to overcome postoperative paresis of intestines and recovery of peristalsis within the first ten postoperative days. It was established that the preparation, given from the second postoperative day in a dose of 2-4 pills daily in women, operated by nonabdominal approach due to the fact that the abdominal cavity was not open during the operation and intestinal peristalsis, was preserved to a great degree. In women, operated by abdominal approach, the optimal time for the onset of treatment was the third postoperative day in a dose of 3 pills daily. The most frequent effect side effect was swelling of the abdomen, which was observed usually during the first day since the onset of treatment. The side effects were minimal after the second day, but they disappeared completely on the fifth postoperative day.

Clinical Trials as Topic

[Suprapubic uterovesical suspension via a hammock made from a flap formed from the vaginal wall--a new surgical method in stress incontinence].

The authors report on their own method, used in women with stress incontinence and included into the group of uterovesical suspensions. The idea of Pereyra and that of Goebell and Stoeckel was applied rationally as the suspension was achieved by a sling from a lambeau, formed from the vaginal wall. The stages of the operation were described in details as well as its advantages in comparison with other operations, used for the same purpose. The personal experience of the authors in this operation was based on 30 women, operated during 1986 and showed very high therapeutic efficiency.

Female

[A case of simultaneous development of leiomyomas of the labia majora and the uterine corpus].

A case of leiomyoma from the left labium major with a diameter of 15 cm is reported. The leiomyoma developed simultaneously with a leiomyoma of the uterine corpus in a 48 year old. The histogenesis, the clinical pattern and the differential diagnosis of this type of tumour of the vulva has been discussed. The necessity to exclude a continuity of the tumour with the abdominal cavity via the inguinal canal is stressed. The latter is relevant as far as the scope and character of the operative procedure is concerned.

Female