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Biomedical subjects

N E Anderson

Publications and source records attributed to N E Anderson.

67 records · Page 4Linked to original sources
PubMed1985

Disabling neurological complications of amiodarone.

Five patients developed neurological symptoms during treatment with amiodarone for intervals ranging between five and 40 months. In each case the daily maintenance dose did not exceed 600 mg. The neurological manifestations included gait ataxia, tremor, polyneuropathy, and myopathy. In all five patients, the neurological symptoms were severe and disabling. In one patient with a myopathy, there was no improvement after amiodarone was withdrawn. The neurological side effects of amiodarone may be disabling and are not always reversible with drug withdrawal. Neurological complications may arise during treatment with usual maintenance doses.

Aged↗
PubMed1985

The natural history and the influence of surgical treatment in syringomyelia.

A retrospective analysis was made of the natural history and treatment of 44 patients with syringomyelia, followed for a median interval of 10 years after diagnosis. Twenty-four patients were treated surgically. Four of 12 patients who had a laminectomy with aspiration of the syrinx or syringostomy, and 7 of 15 patients who underwent decompression and exploration of the cervicomedullary junction, showed sustained improvement or stabilisation of their neurological deficits. When symptoms had been present for more than 2 years, when there was a moderate or severe neurological disability, and when the patient was more than 40 years old, the long-term outlook of posterior fossa surgery was usually poor. Of the 20 patients who did not have an operation, 7 had no further progression in symptoms after presentation and prolonged survival was usual. It is concluded that in many cases syringomyelia is compatible with prolonged survival, and although improvement can follow surgery, its influence on the disease in the long-term is uncertain.

Adolescent↗
PubMed1984

Lower cranial nerve motor function in unilateral vascular lesions of the cerebral hemisphere.

Motor function subserved by cranial nerves V, VII, X, XI, and XII was assessed in 100 patients with hemiparesis due to a unilateral vascular lesion of the cerebral hemisphere. Several of the findings were not described clearly in many of the standard textbooks of neurology. Weakness of sternomastoid when present was always contralateral to the hemiparesis. This emphasises the principle that the cerebral hemisphere controls movement of the body parts in or towards the contralateral half of the body rather than simply the contralateral muscle groups. An apparent exception to this was seen, however, in the small group of patients who had unilateral weakness of the tongue. In those patients deviation of the tongue was towards the hemiparetic side--that is, the cerebral hemisphere controlled the contralateral half of the tongue and hence protrusion towards the ipsilateral side. Mild dysarthria was common with both right and left sided hemiparesis.

Accessory Nerve↗
PubMed1984

The lupus anticoagulant, pulmonary thromboembolism, and fatal pulmonary hypertension.

A patient with a circulating lupus anticoagulant in the absence of systemic lupus erythematosus developed recurrent deep venous thromboses and pulmonary emboli. Pulmonary emboli recurred despite prolonged oral anticoagulant therapy and resulted in fatal pulmonary arterial hypertension. Extended anticoagulant therapy alone may not prevent recurrent thromboembolism in patients with a lupus anticoagulant. Pulmonary thromboembolism may be an important factor in the pathogenesis of pulmonary hypertension in patients with a lupus anticoagulant.

Adult↗
PubMed1981

The clinical significance of right ventricular infarction.

Three patients with inferior myocardial infarction complicated by predominant right ventricular (RV) dysfunction are described. Two patients had clinical and haemodynamic evidence of RV infraction associated with pump failure and improved with infusion of plasma expanders and inotropic agents. A third patient presenting with severe RV failure without left ventricular (LV) dysfunction illustrated the haemodynamic similarities between RV infarction and pericardial tamponade.

Aged↗
PubMed1977

The nutritional status of Auckland children.

The nutritional status of children (and hence the community) was assessed in the five major races in Auckland by height, weight, and head circumference measurements. Under the age of two years Samoan children were significnatly taller and heavier than Europeans and Maori children. No significant racial differences occurred in children between ages two and 13 years. No racial variation in head circumference between races was noted at any age. More children of lower socio-economic class had weights about the 97th percentile especially in Samoan, Cook Island and Niuean children's groups, suggesting they are particularly vulnerable to obesity. Heal circumference of children of low socio-economic status was smaller than that of other children. Similarly non-breast fed children had smaller heads than breast fed children. This suggests these children may have impaired brain growth.

Adolescent↗
PubMedDate not supplied

Missouri rural adolescent pregnancy project (MORAPP).

The purpose of this study was to investigate the pregnancy outcomes and services available to adolescent women in Missouri, comparing rural and urban residents. A secondary analysis of a large public use data set obtained from the Missouri Department of Health was done for the 5-year period 1992 to 1996. Data were collected by county, with each of the 114 counties of the state classified as rural or urban. The SAS program was used for analysis. Results demonstrated definite patterns of similarity and dissimilarity among the teen mothers based on residence, when age and race were controlled. There were over 54,000 births to adolescent mothers in the 5-year study period. Among the outcomes of pregnancy studied were: abortion rates, inadequate weight gain, intrauterine growth retardation, and low-birthweight (LBW) infants. Among the services available to the young mothers that were studied were fertility services, WIC (women, infants, and children supplemental nutrition) program, food stamps, and Medicaid coverage for pregnancy and infant care. The outcomes are probably generalizable to Midwestern, rural/urban states similar to Missouri.

Adolescent↗