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Biomedical subjects

N E Driban

Publications and source records attributed to N E Driban.

11 recordsLinked to original sources

Porokeratotic eccrine ostial and dermal duct nevus.

Comedo-like lesions of the palm, present since birth, are studied electronmicroscopically and their eccrine nature demonstrated. We suggest their inclusion under the name porokeratotic eccrine-ostial and dermal duct nevus previously proposed by Abell and Read.

Adult

Oral manifestations of Sweet's syndrome.

A case of a 38-year-old male with the diagnosis of Sweet's Syndrome is reported. The most significant feature of the patient was manifested by serious lesions in the oral mucosa which persisted throughout the course of the disease. They only improved after the administration of prednisone. Special emphasis is made on the characteristics of the oral manifestations of Sweet's syndrome since they have not been described in detail in the literature.

Adult

Papillon-Lefèvre syndrome. A clinical and therapeutical contribution.

A clinical study of a patient with the Papillon-Lefèvre syndrome is presented. She had identifiable zones where cutaneous involvement was lacking, probably corresponding to areas free from the effects of attrition or trauma. The patient was treated with oral aromatic retinoid Ro 10-9359. An obvious response with marked improvement of the clinical picture was obtained. Combined treatment of the oral cavity with local and systemic medication was carried out. Beneficial effects on involved integuments and on social repercussions are discussed and a new alternative in the management of these patients is proposed.

Administration, Oral

Peripilar keratin casts: a study with the scanning electron microscope.

Two cases of Peripilar keratin casts are presented and the results of a Scanning EM investigation are discussed. The surface of the casts is very irregular and disordered. In the underlying structure of the casts the characteristic image of a "sponge" is observed. The cuticle of the hair beneath is slightly flaky, showing fissures. The hair surface facing the peripilar casts is normal.

Child, Preschool

[Adult progeria (Werner's syndrome)].

Two cases of Progeria of the adult (Werner's Syndrome) are presented. The outstanding characteristic of the mentioned syndrome is an early, progressive and fatal aging of the patient. The study of those two cases suggested, first: a literature search which has shown 140 references to the Werner's Syndrome up to 1971, and second: a clinical features review about general manifestations and specific particularities concerning the skin, cardiovascular system, eyes, glandular system, laboratory tests, etc. Our two patients, who respond to the signs required by Thannhauser for the diagnosis of the Werner's Syndrome, were very useful to clarify the clinical features review undestalren.

Adult

[Sclerema (clinical review apropos of 20 cases)].

Twenty cases of children with Sclerema observed at a Pediatric Service during five years are presented. Their clinical and laboratory traits are integrated in a dermatosis appearing after various and usually serious complications. In the children observed the most frequent finding was represented by sepsis, some of them with disseminated intravascular coagulation syndrome, diarrhoea with dehydration. The therapy applied, fundamentally was based on parenteral solutions, antibiotics and corticoids, was directed by those diseases and not by the presence of sclerema, which however appeared influenced by the supply of the latterly mentioned medicaments. Microscopic disturbances are discussed too, and a reference is made to the incriminabea pathogenic mechanisms.

Humans