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Biomedical subjects

N E Foss

Publications and source records attributed to N E Foss.

9 recordsLinked to original sources

[Multi-injection treatment using an insulin pen].

100 diabetics (50 women and 50 men) with a mean age of 36.8 years (range 17-61) were converted from a conventional insulin regimen to multiple injections of rapidly acting insulin. Metabolic control was evaluated after a mean observation period of 17 months (range 4-32). All patients were sent a questionnaire about the acceptability of the new insulin regimen and about their every day life. Metabolic control, as judged by reduction in HbA1, had improved in most patients. The questionnaire response rate was 79%. 95% of the respondents reported that the insulin pen had made their every day life easier and safer.

Adolescent↗

Physical activity in liver disease and liver function in sportsmen.

Patients with liver disease are often incorrectly restricted in their physical activity. Several studies have shown that physical activity is not detrimental to acute viral hepatitis but it is customary to advise rest in the initial phase of nausea, abdominal pain and fatigue. As soon as these symptoms decline the patient can take part in physical activity. As regards chronic hepatitis and cirrhosis there are divergent views. No restrictions are placed upon patients with chronic active hepatitis in remission. This is also true for the early stage of cirrhosis, while muscle atrophy in more prolonged cases will set a natural limit to the patient's performance. The effect of physical activity on patients with a porto-caval shunt has not been studied. In well trained sportsmen there is no evidence that physical activity within the limits of human performance has an unfavourable effect on liver function.

Adolescent↗

The effect of a standardized work load on 'liver tests' in patients with chronic active hepatitis.

Since opinions differ about the effect of physical activity in chronic liver disease, we performed a submaximal ergometric exercise test in 17 patients with chronic active hepatitis in clinical remission while receiving immunosuppressive therapy and in 5 patients with portacaval shunts. The calculated oxygen consumption was low in most patients. Blood samples were drawn before the exercise and 4 h, 24 h, and 48 h after. No changes occurred in serum ALAT, ASAT, ALP, CK, GT, or prealbumin. The clinical condition was not influenced by the exercise test. We conclude that moderate physical activity, at least of short duration, is well tolerated by patients with chronic active hepatitis.

Adult↗